Rome2Rio

Indianapolis to Ithaca buses

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Trip Overview

The average bus between Indianapolis and Ithaca takes 36h 17m and the fastest bus takes 31h. The bus runs, on average, 5 times per week from Indianapolis to Ithaca. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

36h 17m
Duration
677 mi
Distance
$136
Average price
5 times a week
Frequency

Indianapolis to Ithaca bus times

Buses run 5 times a week between Indianapolis and Ithaca. The earliest departure is at 12:15 AM at night, and the last departure from Indianapolis is at 4:20 PM which arrives into Ithaca at 4:30 PM. All services require a transfer at Columbus and take an average of 36h 17m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USAFlixbus USA31h • 2 changes

Departing Monday, November 16, 2026

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    Arrives next day

    Flixbus USAFlixbus USAFlixbus USA31h • 2 changes

Departing Tuesday, November 17, 2026

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    Arrives +2 days

    Flixbus USAFlixbus USAFlixbus USA2d • 2 changes

Departing Thursday, November 19, 2026

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    Arrives next day

    Flixbus USAFlixbus USAFlixbus USA40h 15m • 2 changes

Departing Friday, November 20, 2026

  •  → 

    Arrives next day

    Flixbus USAFlixbus USAFlixbus USA31h • 2 changes

Frequently asked questions

Want to know about travelling from Indianapolis to Ithaca? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Indianapolis to Ithaca.ExpandLaunch map view
  • Distance: 677.5 mi
  • Duration: 36h 17m

What companies run services between Indianapolis, IN, USA and Ithaca, NY, USA?

You can take a bus from Indianapolis to Ithaca via Columbus and Buffalo in around 15h 40m.

Operators