The average bus between Hyannis and Philadelphia takes 9h 46m and the fastest bus takes 8h 30m. The bus service runs several times per day from Hyannis to Philadelphia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Hyannis and Philadelphia. The earliest departure is at 6:00 AM in the morning, and the last departure from Hyannis is at 9:00 PM which arrives into Philadelphia at 8:30 AM. All services require a transfer at Boston, Bus Terminal South Station and take an average of 9h 46m. The schedules shown below are for the next available departures.


8h 30m • 2 changes


9h • 2 changes


9h 30m • 2 changes


8h 55m • 2 changes


8h 30m • 2 changes


9h • 2 changes


9h 30m • 2 changes


8h 55m • 2 changes


8h 30m • 2 changes


9h • 2 changes


9h 30m • 2 changes


8h 55m • 2 changes


8h 30m • 2 changes


9h • 2 changes


9h 45m • 2 changes


10h • 2 changes


8h 30m • 2 changes


9h • 2 changes


10h • 2 changes
Arrives next day


9h 50m • 2 changes
Want to know about travelling from Hyannis to Philadelphia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hyannis to Philadelphia. However, there are services departing from Hyannis station and arriving at Philadelphia station via Boston South Buses. The journey, including transfers, takes approximately 9h 46m.
Hyannis to Philadelphia bus services, operated by Plymouth & Brockton, depart from Hyannis Transportation Center station.
Hyannis to Philadelphia bus services, operated by Plymouth & Brockton, arrive at Philadelphia station.
The distance between Hyannis and Philadelphia is 452.2 km. The road distance is 687 km.
You can take a bus from Hyannis Transportation Center to Philadelphia via Boston, Bus Terminal South Station, Boston, and New York Midtown in around 9h 48m.