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Hyannis to Manhattan buses

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Trip Overview

The average bus between Hyannis and Manhattan takes 7h and the fastest bus takes 6h 20m. The bus service runs several times per day from Hyannis to Manhattan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

7h
Duration
285 mi
Distance
$71
Average price
Every 2 hours
Frequency

Hyannis to Manhattan bus times

Buses run every 2 hours between Hyannis and Manhattan. The earliest departure is at 5:00 AM in the morning, and the last departure from Hyannis is at 9:00 PM which arrives into Manhattan at 5:30 AM. All services require a transfer at Boston, South Station and take an average of 7h. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

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    Arrives next day

    Plymouth & BrocktonFlixbus USA8h 30m • 1 change

Departing Friday, November 6, 2026

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    Plymouth & BrocktonFlixbus USA7h • 1 change
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    Plymouth & BrocktonFlixbus USA6h 35m • 1 change
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    Plymouth & BrocktonFlixbus USA7h 5m • 1 change
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    Plymouth & BrocktonFlixbus USA6h 20m • 1 change
  • Show more

Departing Saturday, November 7, 2026

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    Plymouth & BrocktonFlixbus USA7h • 1 change
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    Plymouth & BrocktonFlixbus USA6h 35m • 1 change
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    Plymouth & BrocktonFlixbus USA7h 5m • 1 change
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    Plymouth & BrocktonFlixbus USA6h 20m • 1 change
  • Show more

Departing Sunday, November 8, 2026

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    Plymouth & BrocktonFlixbus USA7h • 1 change
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    Plymouth & BrocktonFlixbus USA6h 35m • 1 change
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    Plymouth & BrocktonFlixbus USA7h 5m • 1 change
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    Plymouth & BrocktonFlixbus USA6h 20m • 1 change
  • Show more

Departing Monday, November 9, 2026

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    Plymouth & BrocktonFlixbus USA7h • 1 change
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    Plymouth & BrocktonFlixbus USA6h 35m • 1 change
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    Plymouth & BrocktonFlixbus USA7h 5m • 1 change
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    Plymouth & BrocktonFlixbus USA6h 20m • 1 change
  • Show more

Departing Tuesday, November 10, 2026

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    Plymouth & BrocktonFlixbus USA7h • 1 change
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    Plymouth & BrocktonFlixbus USA6h 35m • 1 change
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    Plymouth & BrocktonFlixbus USA7h 5m • 1 change
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    Plymouth & BrocktonFlixbus USA6h 50m • 1 change
  • Show more

Departing Wednesday, November 11, 2026

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    Plymouth & BrocktonFlixbus USA7h • 1 change
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    Plymouth & BrocktonFlixbus USA6h 20m • 1 change
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    Plymouth & BrocktonFlixbus USA7h 15m • 1 change
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    Plymouth & BrocktonFlixbus USA6h 50m • 1 change
  • Show more

Departing Thursday, November 12, 2026

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    Plymouth & BrocktonFlixbus USA7h • 1 change
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    Plymouth & BrocktonFlixbus USA6h 35m • 1 change
  •  → 

    Plymouth & BrocktonFlixbus USA6h 20m • 1 change
  •  → 

    Plymouth & BrocktonFlixbus USA7h • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Hyannis to Manhattan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Hyannis to Manhattan.ExpandLaunch map view
  • Distance: 284.5 mi
  • Duration: 7h

What companies run services between Hyannis, MA, USA and Manhattan, NY, USA?

You can take a bus from Hyannis Transportation Center to New York Midtown via Boston, South Station and Boston in around 6h 37m.

Operators