The average bus between Hyannis and Manhattan takes 6h 58m and the fastest bus takes 6h 20m. There is a bus service every few hours from Hyannis to Manhattan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Hyannis and Manhattan. The earliest departure is at 4:00 AM at night, and the last departure from Hyannis is at 9:00 PM which arrives into Manhattan at 5:30 AM. All services require a transfer at Boston, Bus Terminal South Station and take an average of 6h 58m. The schedules shown below are for the next available departures.

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6h 40m • 1 change

6h 45m • 1 change

7h 15m • 1 change

7h 35m • 1 change

7h • 1 change

6h 20m • 1 change

6h 40m • 1 change

7h 35m • 1 change

7h • 1 change

6h 20m • 1 change

6h 40m • 1 change

7h 35m • 1 change

7h • 1 change

6h 20m • 1 change

6h 40m • 1 change
Want to know about travelling from Hyannis to Manhattan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hyannis to Manhattan. However, there are services departing from Hyannis station and arriving at Manhattan station via Boston South Buses. The journey, including transfers, takes approximately 6h 58m.
Hyannis to Manhattan bus services, operated by Plymouth & Brockton, depart from Hyannis Transportation Center station.
Hyannis to Manhattan bus services, operated by Plymouth & Brockton, arrive at New York Midtown station.
The distance between Hyannis and Manhattan is 322.9 km. The road distance is 458 km.
You can take a bus from Hyannis Transportation Center to New York Midtown via Boston, Bus Terminal South Station and Boston in around 7h 3m.