The average bus between Hyannis and Madison takes 34h 50m and the fastest bus takes 29h 50m. The bus service runs several times per day from Hyannis to Madison. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Hyannis and Madison. The earliest departure is at 1:00 PM in the afternoon, and the last departure from Hyannis is at 9:00 PM which arrives into Madison at 11:50 AM. All services require a transfer at Boston, Bus Terminal South Station and take an average of 34h 50m. The schedules shown below are for the next available departures.
Arrives next day



28h 50m • 3 changes
Arrives +2 days



38h 50m • 3 changes
Arrives next day



28h 50m • 3 changes
Arrives +2 days



38h 50m • 3 changes
Want to know about travelling from Hyannis to Madison? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hyannis to Madison. However, there are services departing from Hyannis station and arriving at Madison station via Boston South Buses. The journey, including transfers, takes approximately 34h 50m.
Hyannis to Madison bus services, operated by Plymouth & Brockton, depart from Hyannis Transportation Center station.
Hyannis to Madison bus services, operated by Plymouth & Brockton, arrive at 250 N. Lake St - Madison UW Campus station.
The distance between Hyannis and Madison is 1,575.3 km. The road distance is 2,131 km.
You can take a bus from Hyannis Transportation Center to 250 N. Lake St - Madison UW Campus via Boston, Bus Terminal South Station, Boston, New York Midtown, Chicago Bus Station, and W Jackson Blvd, after S Clinton St in around 29h 40m.