The average bus between Hyannis and Frederick takes 18h 21m and the fastest bus takes 15h 10m. The bus service runs several times per day from Hyannis to Frederick. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Hyannis and Frederick. The earliest departure is at 3:30 PM in the afternoon, and the last departure from Hyannis is at 5:15 PM which arrives into Frederick at 12:30 PM. All services require a transfer at Peter Pan Bus Terminal and take an average of 18h 21m. The schedules shown below are for the next available departures.
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15h 10m • 3 changes
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26h 10m • 3 changes
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15h 10m • 3 changes
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26h 10m • 3 changes
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15h 10m • 3 changes
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19h 15m • 3 changes
Arrives next day



15h 10m • 3 changes
Arrives next day



19h 15m • 3 changes
Want to know about travelling from Hyannis to Frederick? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hyannis to Frederick. However, there are services departing from Hyannis station and arriving at Frederick station via Providence Bus Terminal. The journey, including transfers, takes approximately 18h 21m.
Hyannis to Frederick bus services, operated by Peter Pan Bus Lines, depart from Hyannis Transportation Center station.
Hyannis to Frederick bus services, operated by Peter Pan Bus Lines, arrive at Frederick Bus Station.
The distance between Hyannis and Frederick is 651.6 km. The road distance is 879 km.
You can take a bus from Hyannis Transportation Center to Frederick Bus Station via Peter Pan Bus Terminal, Port Authority Bus Terminal, and Baltimore Downtown Bus Terminal, Baltimore, MD in around 12h 47m.