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How to get fromHyannis to Frederickby plane, bus, train, bus (Flixbus), car, train (Amtrak), or bus (Greyhound)

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There are 9 ways to get from Hyannis to Frederick by plane, bus, train, bus (Flixbus), car, train (Amtrak), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Barnstable Municipal Airport to Ronald Reagan Washington National Airport, bus

    best
    1. Fly from Barnstable Municipal Airport (HYA) to Ronald Reagan Washington National Airport (DCA)plane plane HYA - DCA
    2. Take the bus from SHADY GROVE & station to Frederick Marc Stationbus bus
    4h 39m
    $104–579

  2. Drive 476.1 mi

    cheapest
    1. Drive from Hyannis to Frederickcar car 476.1 mi
    9h 16m
    $87–126

  3. Bus, train via New York

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to BWI Thurgood Marshalltrain train
    4. Take the bus from BWI Amtrak Station to Frederick Transit Centerbus bus Bwi
    11h 53m
    $175–1,578

  4. Bus via Boston

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the bus from New York Midtown to Baltimore Downtown Bus Stationbus bus
    4. Take the bus from Baltimore Downtown Bus Terminal, Baltimore, MD to Frederick Bayrunner Officebus bus
    12h 22m
    $157–250

  5. Bus to Boston Logan Airport, fly to Baltimore-Washington International Airport, bus

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Baltimore-Washington International Airport (BWI)plane plane BOS - BWI
    3. Take the bus from Baltimore Airport to Frederick Bus Stationbus bus
    6h 27m
    $226–1,130

  6. Bus to Boston Logan Airport, fly to Washington Dulles International Airport, bus

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Washington Dulles International Airport (IAD)plane plane BOS - IAD
    3. Take the bus from Market St & Harrison St to Frederick Transit Stationbus bus
    7h 26m
    $520–1,165

  7. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Washington Union Stationtrain train
    3. Take the train from Washington Union Station to FREDERICK MARC wbtrain train
    12h 21m
    $169–347

  8. Train

    1. Take the train from Hyannis to South Stationtrain train
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Washington Union Stationtrain train
    4. Take the train from Washington Union Station to FREDERICK MARC wbtrain train
    13h 12m
    $127–934

  9. Bus

    1. Take the bus from Hyannis Transportation Center to Providence Bus Terminalbus bus
    2. Take the bus from Peter Pan Bus Terminal to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Baltimore Downtown Bus Stationbus bus
    4. Take the bus from Baltimore Downtown Bus Station to Frederick Bus Stationbus bus
    14h 24m
    $181–365

Hyannis to Frederick by bus, foot, and train

Calendar52Weekly Services
Duration11h 53mAverage Duration
Ticket$175Cheapest Price
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Questions & Answers

Map of how to get from Hyannis to Frederick.ExpandLaunch map view
  • Distance: 457.3 mi
  • Duration: 4h 39m

What companies run services between Hyannis, MA, USA and Frederick, MD, USA?

You can take a bus from Hyannis Transportation Center to Frederick Bayrunner Office via Boston, South Station, Boston, New York Midtown, and Baltimore Downtown Bus Terminal, Baltimore, MD in around 12h 22m. Alternatively, you can take a train from Hyannis to FREDERICK MARC wb via South Station, Boston, Ny Moynihan Train Hall At Penn Station, and Washington Union Station in around 13h 12m.

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