The average bus between Hyannis and Waltham takes 2h 42m and the fastest bus takes 2h 27m. The bus service runs several times per day from Hyannis to Waltham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Hyannis and Waltham. The earliest departure is at 4:00 AM at night, and the last departure from Hyannis is at 4:00 PM which arrives into Waltham at 6:43 PM. All services require a transfer at Boston, Bus Terminal South Station and take an average of 2h 42m. The schedules shown below are for the next available departures.

2h 27m • 1 change

2h 28m • 1 change

2h 36m • 1 change

2h 55m • 1 change

2h 27m • 1 change

2h 28m • 1 change

2h 36m • 1 change

2h 55m • 1 change

2h 27m • 1 change

2h 28m • 1 change

2h 36m • 1 change

2h 55m • 1 change

2h 27m • 1 change

2h 28m • 1 change

2h 36m • 1 change

2h 55m • 1 change
Want to know about travelling from Hyannis to Waltham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hyannis to Waltham. However, there are services departing from Hyannis station and arriving at Waltham station via Boston South Buses. The journey, including transfers, takes approximately 2h 42m.
Hyannis to Waltham bus services, operated by Plymouth & Brockton, depart from Hyannis Transportation Center station.
Hyannis to Waltham bus services, operated by Plymouth & Brockton, arrive at Moody St @ Carter St station.
The distance between Hyannis and Waltham is 112.5 km. The road distance is 139 km.
You can take a bus from Hyannis Transportation Center to Moody St @ Carter St via Boston, Bus Terminal South Station and Otis St @ Summer St in around 3h 41m.