The average bus between Hyannis and Waltham takes 3h 14m and the fastest bus takes 2h 30m. The bus service runs several times per day from Hyannis to Waltham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Hyannis and Waltham. The earliest departure is at 4:30 AM at night, and the last departure from Hyannis is at 5:15 PM which arrives into Waltham at 7:59 PM. All services require a transfer at Boston and take an average of 3h 14m. The schedules shown below are for the next available departures.

2h 34m • 1 change

2h 30m • 1 change

2h 51m • 1 change

3h 58m • 1 change

2h 34m • 1 change

2h 30m • 1 change

2h 51m • 1 change

3h 58m • 1 change

2h 34m • 1 change

2h 30m • 1 change

2h 51m • 1 change

3h 58m • 1 change

2h 34m • 1 change

2h 30m • 1 change

2h 51m • 1 change

3h 58m • 1 change

2h 34m • 1 change

2h 30m • 1 change

2h 51m • 1 change

3h 58m • 1 change
Want to know about travelling from Hyannis to Waltham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Hyannis to Waltham. However, there are services departing from Hyannis station and arriving at Waltham station via Boston. The journey, including transfers, takes approximately 3h 14m.
Hyannis to Waltham bus services, operated by Peter Pan Bus Lines, depart from Hyannis station.
Hyannis to Waltham bus services, operated by Peter Pan Bus Lines, arrive at Boston station.
The distance between Hyannis and Waltham is 112.5 km. The road distance is 132 km.
Peter Pan Bus Lines operates a bus from Hyannis to Boston every 3 hours. Tickets cost $15–40 and the journey takes 1h 30m.