The average bus between Holyoke and Hyannis takes 5h 46m and the fastest bus takes 4h 18m. The bus service runs several times per day from Holyoke to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Holyoke and Hyannis. The earliest departure is at 8:26 AM in the morning, and the last departure from Holyoke is at 8:16 PM which arrives into Hyannis at 8:15 AM. All services require a transfer at Union Station Bay 9 and take an average of 5h 46m. The schedules shown below are for the next available departures.


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5h 18m • 2 changes
Want to know about travelling from Holyoke to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Holyoke to Hyannis. However, there are services departing from Holyoke station and arriving at Hyannis station via Boston. The journey, including transfers, takes approximately 5h 46m.
Holyoke to Hyannis bus services, operated by PVTA, depart from Springfield Union Station.
Holyoke to Hyannis bus services, operated by PVTA, arrive at Hyannis Transportation Center station.
The distance between Holyoke and Hyannis is 202.5 km. The road distance is 274 km.
You can take a bus from Maple / Hampshire to Hyannis Transportation Center via Union Station Bay 9, Springfield Union Station, Boston, and Boston South Buses in around 5h 28m.