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Holyoke to Hyannis buses

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Trip Overview

The average bus between Holyoke and Hyannis takes 5h 54m and the fastest bus takes 4h 35m. The bus service runs several times per day from Holyoke to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 54m
Duration
170 mi
Distance
$37
Average price
Every 4 hours
Frequency

Bus

best
  1. Take the bus from Springfield Union Station to Bostonbus bus Greyhound US0270s / ...
  2. Take the bus from Boston to Hyannisbus bus Bz 0956 / ...
6h 17m
$28–62

Holyoke to Hyannis bus times

Buses run every 4 hours between Holyoke and Hyannis. The earliest departure is at 7:20 AM in the morning, and the last departure from Holyoke is at 10:30 PM which arrives into Hyannis at 9:35 AM. All services require a transfer at Union Station Bay 9 and take an average of 5h 54m. The schedules shown below are for the next available departures.

Departing Friday, October 23, 2026

  •  → 

    PVTAPeter Pan Bus LinesPeter Pan Bus Lines5h 10m • 2 changes

  •  → 

    PVTAGreyhound USAPeter Pan Bus Lines5h 5m • 2 changes

  •  → 

    PVTAFlixbus USAPeter Pan Bus Lines4h 35m • 2 changes

  •  → 

    PVTAPeter Pan Bus LinesPeter Pan Bus Lines5h 20m • 2 changes
  • Show more

Departing Saturday, October 24, 2026

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    PVTAPeter Pan Bus LinesPeter Pan Bus Lines5h 15m • 2 changes

  •  → 

    PVTAGreyhound USAPeter Pan Bus Lines5h 5m • 2 changes

  •  → 

    PVTAFlixbus USAPeter Pan Bus Lines4h 35m • 2 changes

  •  → 

    PVTAPeter Pan Bus LinesPeter Pan Bus Lines4h 50m • 2 changes
  • Show more

Departing Sunday, October 25, 2026

  •  → 

    PVTAFlixbus USAPeter Pan Bus Lines4h 35m • 2 changes

  •  → 

    PVTAPeter Pan Bus LinesPeter Pan Bus Lines4h 50m • 2 changes

  •  → 

    PVTAGreyhound USAPeter Pan Bus Lines5h • 2 changes

  •  → 

    PVTAFlixbus USAPeter Pan Bus Lines4h 40m • 2 changes
  • Show more

Departing Monday, October 26, 2026

  •  → 

    PVTAPeter Pan Bus LinesPeter Pan Bus Lines5h 10m • 2 changes

  •  → 

    PVTAGreyhound USAPeter Pan Bus Lines5h 5m • 2 changes

  •  → 

    PVTAFlixbus USAPeter Pan Bus Lines4h 35m • 2 changes

  •  → 

    PVTAPeter Pan Bus LinesPeter Pan Bus Lines5h 20m • 2 changes
  • Show more

Departing Tuesday, October 27, 2026

  •  → 

    PVTAPeter Pan Bus LinesPeter Pan Bus Lines5h 10m • 2 changes

  •  → 

    PVTAGreyhound USAPeter Pan Bus Lines5h 5m • 2 changes

  •  → 

    PVTAGreyhound USAPeter Pan Bus Lines6h 5m • 2 changes

  •  → 

    PVTAPeter Pan Bus LinesPeter Pan Bus Lines5h 20m • 2 changes
  • Show more

Departing Wednesday, October 28, 2026

  •  → 

    PVTAPeter Pan Bus LinesPeter Pan Bus Lines5h 10m • 2 changes

  •  → 

    PVTAGreyhound USAPeter Pan Bus Lines5h 5m • 2 changes

  •  → 

    PVTAFlixbus USAPeter Pan Bus Lines4h 35m • 2 changes

  •  → 

    PVTAPeter Pan Bus LinesPeter Pan Bus Lines5h 20m • 2 changes
  • Show more

Departing Thursday, October 29, 2026

  •  → 

    PVTAPeter Pan Bus LinesPeter Pan Bus Lines5h 10m • 2 changes

  •  → 

    PVTAGreyhound USAPeter Pan Bus Lines5h 5m • 2 changes

  •  → 

    PVTAFlixbus USAPeter Pan Bus Lines4h 35m • 2 changes

  •  → 

    PVTAPeter Pan Bus LinesPeter Pan Bus Lines5h 20m • 2 changes
  • Show more

Frequently asked questions

Want to know about travelling from Holyoke to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Holyoke to Hyannis.ExpandLaunch map view
  • Distance: 170.1 mi
  • Duration: 5h 54m

What companies run services between Holyoke, MA, USA and Hyannis, MA, USA?

You can take a bus from HTC Bay 7 to Hyannis via Union Station Bay 9, Springfield Union Station, and Boston in around 6h 17m.

Operators