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Maine to Hyannis buses

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Trip Overview

The average bus between Maine and Hyannis takes 5h 37m and the fastest bus takes 4h 42m. The bus service runs several times per day from Maine to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 37m
Duration
181 mi
Distance
$61
Average price
Every 2 hours
Frequency

Maine to Hyannis bus times

Buses run every 2 hours between Maine and Hyannis. The earliest departure is at 5:33 AM in the morning, and the last departure from Maine is at 10:15 PM which arrives into Hyannis at 8:15 AM. All services require a transfer at Portland, ME and take an average of 5h 37m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

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    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton5h 55m • 2 changes
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    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton5h 55m • 2 changes
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    Greater Portland Metro BusConcord Coach LinesPlymouth & Brockton5h 55m • 2 changes
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    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton5h 55m • 2 changes
  • Show more

Departing Monday, November 16, 2026

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    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton4h 42m • 2 changes
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    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton5h 25m • 2 changes
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    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton5h • 2 changes
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    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton5h 20m • 2 changes
  • Show more

Departing Tuesday, November 17, 2026

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    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton4h 42m • 2 changes
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    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton5h 25m • 2 changes
  •  → 

    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton5h • 2 changes
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    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton5h 20m • 2 changes
  • Show more

Departing Wednesday, November 18, 2026

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    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton4h 42m • 2 changes
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    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton5h 25m • 2 changes
  •  → 

    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton5h • 2 changes
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    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton5h 20m • 2 changes
  • Show more

Departing Thursday, November 19, 2026

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    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton4h 42m • 2 changes
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    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton5h 25m • 2 changes
  •  → 

    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton5h • 2 changes
  •  → 

    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton5h 20m • 2 changes
  • Show more

Departing Friday, November 20, 2026

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    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton4h 42m • 2 changes
  •  → 

    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton5h 25m • 2 changes
  •  → 

    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton5h • 2 changes
  •  → 

    Greater Portland Metro BusAmtrak ThruwayPlymouth & Brockton5h 20m • 2 changes
  • Show more

Frequently asked questions

Want to know about travelling from Maine to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Maine to Hyannis.ExpandLaunch map view
  • Distance: 181.1 mi
  • Duration: 5h 37m

What companies run services between Maine, USA and Hyannis, MA, USA?

You can take a bus from Portland Public Library to Hyannis Transportation Center via Portland, ME, Boston, MA - South Station, and Boston South Buses in around 5h 4m.

Operators