The average bus between Harlem and Rochester takes 7h 41m and the fastest bus takes 7h 2m. The bus service runs several times per day from Harlem to Rochester. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Harlem and Rochester. The earliest departure is at 3:47 AM at night, and the last departure from Harlem is at 7:08 PM which arrives into Rochester at 2:25 AM. All services require a transfer at 7 Av/W 41 St and take an average of 7h 41m. The schedules shown below are for the next available departures.

7h 58m • 1 change

8h 7m • 1 change

8h 6m • 1 change
Arrives next day

7h 22m • 1 change

7h 7m • 1 change

7h 58m • 1 change

8h 14m • 1 change
Arrives next day

7h 17m • 1 change

7h 7m • 1 change

7h 58m • 1 change

8h 14m • 1 change
Arrives next day

7h 17m • 1 change

7h 7m • 1 change

7h 58m • 1 change

8h 14m • 1 change
Arrives next day

7h 17m • 1 change
Want to know about travelling from Harlem to Rochester? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Harlem to Rochester. However, there are services departing from Harlem station and arriving at Rochester station via Rochester. The journey, including transfers, takes approximately 7h 41m.
Harlem to Rochester bus services, operated by MTA Bus Company, depart from New York station.
Harlem to Rochester bus services, operated by MTA Bus Company, arrive at Rochester station.
The distance between Harlem and Rochester is 400.1 km. The road distance is 627 km.
Trailways operates a bus from New York to Rochester every 4 hours. Tickets cost $50–230 and the journey takes 6h 25m.