The average bus between Harlem and Niagara Falls takes 10h 26m and the fastest bus takes 10h. The bus service runs several times per day from Harlem to Niagara Falls. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Harlem and Niagara Falls. The earliest departure is at 6:55 AM in the morning, and the last departure from Harlem is at 11:10 PM which arrives into Niagara Falls at 9:30 AM. All services require a transfer at 42 St-Port Authority Bus Terminal and take an average of 10h 26m. The schedules shown below are for the next available departures.

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Want to know about travelling from Harlem to Niagara Falls? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Harlem to Niagara Falls. However, there are services departing from Harlem station and arriving at Niagara Falls station via Buffalo. The journey, including transfers, takes approximately 10h 26m.
Harlem to Niagara Falls bus services, operated by MTA Bus Company, depart from New York station.
Harlem to Niagara Falls bus services, operated by MTA Bus Company, arrive at Buffalo station.
The distance between Harlem and Niagara Falls is 493.1 km. The road distance is 789 km.
Trailways operates a bus from New York to Buffalo every 4 hours. Tickets cost $60–280 and the journey takes 8h.