Rome2Rio

Guelph to Pittsburgh buses

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Trip Overview

The average bus between Guelph and Pittsburgh takes 33h 8m and the fastest bus takes 33h. The bus runs, on average, 6 times per week from Guelph to Pittsburgh. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

33h 8m
Duration
349 mi
Distance
$105
Average price
6 times a week
Frequency

Guelph to Pittsburgh bus times

Buses run 6 times a week between Guelph and Pittsburgh. The earliest departure is at 6:45 AM in the morning, and the last departure from Guelph is at 7:10 AM which arrives into Pittsburgh at 4:10 PM. All services require a transfer at Winston Churchill Transitway Station and take an average of 33h 8m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    GO TransitTrailwaysGreyhound USAGreyhound USA33h • 3 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    GO TransitTrailwaysGreyhound USAGreyhound USA33h • 3 changes

Departing Friday, November 13, 2026

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    Arrives next day

    GO TransitTrailwaysGreyhound USAGreyhound USA33h • 3 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    GO TransitTrailwaysGreyhound USAGreyhound USA33h 25m • 3 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    GO TransitTrailwaysGreyhound USAGreyhound USA33h 25m • 3 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    GO TransitTrailwaysGreyhound USAGreyhound USA33h • 3 changes

Frequently asked questions

Want to know about travelling from Guelph to Pittsburgh? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Guelph to Pittsburgh.ExpandLaunch map view
  • Distance: 348.9 mi
  • Duration: 33h 8m

What companies run services between Guelph, ON, Canada and Pittsburgh, PA, USA?

You can take a bus from Guelph Central GO Bus to Pittsburgh Intermodal Station via Winston Churchill Transitway Station, Mississauga, Buffalo, and Erie in around 12h 9m.

Operators