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How to get fromGuelph to Pittsburghby train, plane, bus, bus (Greyhound), train (Amtrak) or car

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There are 6 ways to get from Guelph to Pittsburgh by train, plane, bus, bus (Greyhound), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, fly, bus

    best
    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Pittsburgh International Airport (PIT)plane plane YYZ - PIT
    3. Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus bus
    6h 24m

  2. Bus

    cheapest
    1. Take the bus from University of Guelph to Winston Churchill Transitway Stationbus bus 29
    2. Take the bus from Mississauga to Buffalobus bus
    3. Take the bus from Buffalo, NY to Youngstown, OHbus bus
    4. Take the bus from Youngstown Bus Stop to Pittsburgh Intermodal Stationbus bus
    10h 49m
    $65–147

  3. Train

    1. Take the train from Guelph Central GO to Toronto Union Stationtrain train Ki
    2. Take the train from Toronto Union Station to Buffalotrain train
    3. Take the train from Buffalo Depew Station to Cleveland Amtraktrain train
    4. Take the train from Cleveland Amtrak to Pittsburgh Amtrak Stationtrain train
    14h 51m
    $78–303

  4. Drive 308.7 mi

    1. Drive from Guelph to Pittsburghcar car 308.7 mi
    5h 38m
    $71–103

  5. Bus via Erie

    1. Take the bus from Guelph Central GO Bus to Winston Churchill Transitway Stationbus bus 29
    2. Take the bus from Mississauga to Buffalobus bus
    3. Take the bus from Buffalo to Eriebus bus
    4. Take the bus from Erie to Pittsburgh Intermodal Stationbus bus
    12h 9m
    $71–139

  6. Bus #2

    1. Take the bus from Guelph Central GO Bus to Winston Churchill Transitway Stationbus bus 29
    2. Take the bus from Mississauga to Buffalobus bus
    3. Take the bus from Buffalo to Pittsburghbus bus
    13h 24m
    $68–244

Guelph to Pittsburgh by bus

Calendar7Weekly Buses
Duration10h 49mAverage Duration
Ticket$65Cheapest Price
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Questions & Answers

What companies run services between Guelph, ON, Canada and Pittsburgh, PA, USA?

You can take a bus from University of Guelph to Pittsburgh Intermodal Station via Winston Churchill Transitway Station, Mississauga, Buffalo, NY, Youngstown, OH, and Youngstown Bus Stop in around 10h 49m. Alternatively, you can take a train from Guelph Central GO to Pittsburgh Amtrak Station via Toronto Union Station, Buffalo Depew Station, and Cleveland Amtrak in around 14h 51m.

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