Rome2Rio

Guelph to Indianapolis buses

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Trip Overview

The average bus between Guelph and Indianapolis takes 26h 21m and the fastest bus takes 23h 58m. The bus runs, on average, 3 times per week from Guelph to Indianapolis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

26h 21m
Duration
492 mi
Distance
$92
Average price
3 times a week
Frequency

Guelph to Indianapolis bus times

Buses run 3 times a week between Guelph and Indianapolis. The earliest departure is at 6:52 PM in the evening, and the last departure from Guelph is at 10:27 PM which arrives into Indianapolis at 10:25 PM. All services require a transfer at Victoria / Bingemans Centre Dr. and take an average of 26h 21m. The schedules shown below are for the next available departures.

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    GO TransitGO TransitFlixbus USABarons Bus23h 58m • 3 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    GO TransitGO TransitFlixbus USABarons Bus27h 33m • 3 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    GO TransitGO TransitFlixbus USABarons Bus27h 33m • 3 changes

Frequently asked questions

Want to know about travelling from Guelph to Indianapolis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Guelph to Indianapolis.ExpandLaunch map view
  • Distance: 491.9 mi
  • Duration: 26h 21m

What companies run services between Guelph, ON, Canada and Indianapolis, IN, USA?

You can take a bus from Guelph Central GO Bus to Indianapolis via Victoria / Bingemans Centre Dr., Kitchener, and Detroit in around 13h 29m.

Operators