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How to get fromGuelph to Indianapolisby train, plane, bus, train (Amtrak), car, shuttle or bus (Flixbus)

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There are 9 ways to get from Guelph to Indianapolis by train, plane, bus, train (Amtrak), car, shuttle, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Toronto Pearson International Airport, fly

    best
    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Indianapolis (IND)plane plane YYZ - IND
    6h 19m
    $183–565

  2. Bus

    cheapest
    1. Take the bus from Kitchener to Detroit Bus Stationbus bus FlixBus N2710
    2. Take the bus from Detroit, MI to Indianapolis, INbus bus Detroit
    14h
    $58–120

  3. Train, bus via Detroit

    1. Take the train from Guelph to Londontrain train
    2. Take the train from London to Windsortrain train
    3. Take the bus from Detroit, MI to Indianapolis, INbus bus
    11h 48m
    $68–238

  4. Train

    1. Take the train from Guelph to Sarniatrain train
    2. Take the train from Port Huron Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    17h 8m
    $137–350

  5. Drive 460.2 mi

    1. Drive from Guelph to Indianapoliscar car 460.2 mi
    8h 14m
    $106–153

  6. Train to Toronto Island Airport, fly

    1. Take the train from Guelph Central GO to Union Station GOtrain train
    2. Fly from Toronto Island Airport (YTZ) to Indianapolis (IND)plane plane YTZ - IND
    9h 5m
    $256–529

  7. Train to London International Airport, fly

    1. Take the train from Guelph to Londontrain train
    2. Fly from London International Airport (YXU) to Indianapolis (IND)plane plane YXU - IND
    12h 39m
    $170–1,039

  8. Train, shuttle to Buffalo Niagara International Airport, fly

    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle bus
    3. Fly from Buffalo Niagara International Airport (BUF) to Indianapolis (IND)plane plane BUF - IND
    10h 5m
    $223–885

  9. Train, bus

    1. Take the train from Guelph to Londontrain train
    2. Take the bus from London to Detroit Bus Stationbus bus
    3. Take the bus from Detroit, MI to Indianapolis, INbus bus
    13h 27m
    $60–177

Guelph to Indianapolis by train, car, and bus

Calendar7Weekly Services
Duration11h 48mAverage Duration
Ticket$68Cheapest Price
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Questions & Answers

What companies run services between Guelph, ON, Canada and Indianapolis, IN, USA?

You can take a train from Guelph to Indianapolis via Sarnia, Port Huron Station, and Chicago Union Station in around 17h 8m. Alternatively, you can take a bus from Guelph Central GO Bus to Indianapolis, IN via University of Waterloo Terminal, Kitchener GO Bus, Kitchener, and Detroit, MI in around 14h.

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