Rome2Rio

Des Moines to Cincinnati buses

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Trip Overview

The bus between Des Moines and Cincinnati takes 20h 50m. The bus runs, on average, 6 times per week from Des Moines to Cincinnati. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

20h 50m
Duration
608 mi
Distance
$129
Average price
6 times a week
Frequency

Des Moines to Cincinnati bus times

Buses run 6 times a week between Des Moines and Cincinnati. The service departs Des Moines at 7:50 AM in the morning, which arrives into Cincinnati at 05:40:00. All services require a transfer at Indianapolis and take an average of 20h 50m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

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    Arrives next day

    Greyhound USABarons BusBarons Bus20h 50m • 2 changes

Departing Monday, November 16, 2026

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    Arrives next day

    Greyhound USABarons BusBarons Bus20h 50m • 2 changes

Departing Tuesday, November 17, 2026

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    Arrives next day

    Greyhound USABarons BusBarons Bus20h 50m • 2 changes

Departing Wednesday, November 18, 2026

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    Arrives next day

    Greyhound USABarons BusBarons Bus20h 50m • 2 changes

Departing Thursday, November 19, 2026

  •  → 

    Arrives next day

    Greyhound USABarons BusBarons Bus20h 50m • 2 changes

Frequently asked questions

Want to know about travelling from Des Moines to Cincinnati? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Des Moines to Cincinnati.ExpandLaunch map view
  • Distance: 608.2 mi
  • Duration: 20h 50m

What companies run services between Des Moines, IA, USA and Cincinnati, OH, USA?

You can take a bus from Des Moines to Cincinnati via Indianapolis and Cincinnati in around 14h 35m.

Operators