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How to get fromDes Moines to Cincinnatiby plane, bus (Greyhound, Flixbus) or car

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There are 4 ways to get from Des Moines to Cincinnati by plane, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Covington

    best
    1. Fly from Des Moines (DSM) to Covington (CVG)plane plane DSM - CVG
    4h 43m
    $210–1,223
  2. Bus

    cheapest
    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123 / ...
    2. Take the bus from Chicago Bus Station to Cincinnatibus bus FlixBus 2514
    13h 50m
    $84–159
  3. Drive 572.5 mi

    1. Drive from Des Moines to Cincinnaticar car 572.5 mi
    9h 44m
    $105–151
  4. Fly to Blue Grass Airport, drive

    1. Fly from Des Moines (DSM) to Blue Grass Airport (LEX)plane plane DSM - LEX
    2. Drive from Lexington-Airport-LEX to Cincinnaticar car
    5h 44m
    $263–1,444

Des Moines to Cincinnati by bus

Calendar6Weekly Buses
Duration13h 50mAverage Duration
Ticket$84Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Cincinnati, OH, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Des Moines (DSM) to Covington (CVG) hourly. Alternatively, you can take a bus from Des Moines to Cincinnati via Chicago Bus Station in around 13h 50m.

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