The average bus between Des Moines and Buffalo takes 35h 59m and the fastest bus takes 35h 55m. The bus runs, on average, 6 times per week from Des Moines to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Des Moines and Buffalo. The earliest departure is at 9:20 AM in the morning, and the last departure from Des Moines is at 9:45 AM which arrives into Buffalo at 10:40 PM. All services require a transfer at Chicago and take an average of 35h 59m. The schedules shown below are for the next available departures.
Want to know about travelling from Des Moines to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Des Moines to Buffalo. However, there are services departing from Des Moines station and arriving at Buffalo station via Chicago Bus Station and Cleveland station. The journey, including transfers, takes approximately 35h 59m.
Des Moines to Buffalo bus services, operated by Greyhound USA, depart from Des Moines station.
Des Moines to Buffalo bus services, operated by Barons Bus, arrive at Buffalo station.
Book your Des Moines to Buffalo bus tickets online with Omio.
The distance between Des Moines and Buffalo is 1219.4 km. The road distance is 1366 km.
You can take a bus from Des Moines to Buffalo via Chicago and Cleveland in around 19h 10m.
