Rome2Rio

Bethesda to Buffalo buses

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Trip Overview

The average bus between Bethesda and Buffalo takes 17h 5m and the fastest bus takes 13h 5m. There is at least one bus per day from Bethesda to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

17h 5m
Duration
735 mi
Distance
$159
Average price
Once daily
Frequency

Bethesda to Buffalo bus times

Buses run once daily between Bethesda and Buffalo. The earliest departure is at 10:10 AM in the morning, and the last departure from Bethesda is at 5:10 PM which arrives into Buffalo at 8:45 AM. All services require a transfer at New York Penn Station and take an average of 17h 5m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    Tripper BusFlixbus USA18h 50m • 1 change

Departing Wednesday, November 11, 2026

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    Arrives next day

    Tripper BusFlixbus USA18h 50m • 1 change

Departing Thursday, November 12, 2026

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    Arrives next day

    Tripper BusFlixbus USA15h 35m • 1 change

Departing Friday, November 13, 2026

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    Arrives next day

    Tripper BusFlixbus USA18h 50m • 1 change
  •  → 

    Arrives next day

    Tripper BusFlixbus USA13h 5m • 1 change

Departing Saturday, November 14, 2026

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    Arrives next day

    Tripper BusFlixbus USA18h 50m • 1 change

Departing Sunday, November 15, 2026

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    Arrives next day

    Tripper BusFlixbus USA17h • 1 change
  •  → 

    Arrives next day

    Tripper BusFlixbus USA15h 45m • 1 change

Frequently asked questions

Want to know about travelling from Bethesda to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Bethesda to Buffalo.ExpandLaunch map view
  • Distance: 735.1 mi
  • Duration: 17h 5m

What companies run services between Bethesda, MD, USA and Buffalo, NY, USA?

You can take a bus from Bethesda, MD to Buffalo via New York Penn Station and New York Midtown in around 13h 40m.

Operators