The average bus between Como and Messina takes 21h 7m and the fastest bus takes 20h 20m. The bus service runs several times per day from Como to Messina. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Como and Messina. The earliest departure is at 6:25 AM in the morning, and the last departure from Como is at 9:30 PM which arrives into Messina at 7:50 PM. All services require a transfer, and take on average 21h 7m. The schedules shown below are for the next available departures.
Arrives next day

23h 55m • 1 change
Arrives next day

22h 20m • 1 change
Arrives next day

23h 55m • 1 change
Arrives next day

22h 20m • 1 change
Arrives next day

23h 55m • 1 change
Arrives next day

22h 20m • 1 change
Arrives next day

23h 55m • 1 change
Arrives next day

22h 20m • 1 change
Want to know about travelling from Como to Messina? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Como to Messina. However, there are services departing from Como station and arriving at Messina station via Milan. The journey, including transfers, takes approximately 21h 7m.
Como to Messina bus services, operated by FlixBus, depart from Como station.
Como to Messina bus services, operated by FlixBus, arrive at Messina station.
Book your Como to Messina bus tickets online with FlixBus.
The distance between Como and Messina is 1,000.5 km. The road distance is 1,304 km.
You can take a bus from Como to Messina via Milano, Autostazione Lampugnano in around 19h 30m.