The average bus between Lugano and Messina takes 22h 30m and the fastest bus takes 22h 15m. The bus service runs several times per day from Lugano to Messina. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Lugano and Messina. The earliest departure is at 5:35 AM in the morning, and the last departure from Lugano is at 7:35 PM which arrives into Messina at 7:50 PM. All services require a transfer, and take on average 22h 30m. The schedules shown below are for the next available departures.
Arrives next day

24h 45m • 1 change
Arrives next day

24h 15m • 1 change
Arrives next day

24h 45m • 1 change
Arrives next day

24h 15m • 1 change
Arrives next day

24h 45m • 1 change
Arrives next day

24h 15m • 1 change
Arrives next day

24h 45m • 1 change
Arrives next day

24h 15m • 1 change
Want to know about travelling from Lugano to Messina? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lugano to Messina. However, there are services departing from Lugano station and arriving at Messina station via Milan. The journey, including transfers, takes approximately 22h 30m.
Lugano to Messina bus services, operated by FlixBus, depart from Lugano station.
Lugano to Messina bus services, operated by FlixBus, arrive at Messina station.
Book your Lugano to Messina bus tickets online with FlixBus.
The distance between Lugano and Messina is 1,024.4 km. The road distance is 1,362 km.
You can take a bus from Lugano to Messina via Milano, Autostazione Lampugnano in around 19h 25m.