The average bus between Rome, Termini and Messina takes 11h 18m and the fastest bus takes 9h 56m. The bus service runs several times per day from Rome, Termini to Messina. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Rome, Termini and Messina. The earliest departure is at 12:17 AM at night, and the last departure from Rome, Termini is at 11:55 PM which arrives into Messina at 11:10 AM. All services require a transfer, and take on average 11h 18m. The schedules shown below are for the next available departures.

10h 25m • 1 change

11h 35m • 1 change
Arrives next day

10h 3m • 1 change

10h 52m • 1 change

11h 27m • 1 change
Arrives next day

10h 6m • 1 change
Want to know about travelling from Rome, Termini to Messina? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Rome, Termini to Messina. However, there are services departing from Rome, Termini station and arriving at Messina station via Messina. The journey, including transfers, takes approximately 11h 18m.
Rome, Termini to Messina bus services, operated by ATAC S.p.A. Azienda per la mobilità, depart from Roma, Autostazione Tiburtina station.
Rome, Termini to Messina bus services, operated by ATAC S.p.A. Azienda per la mobilità, arrive at Messina station.
The distance between Rome, Termini and Messina is 487.3 km. The road distance is 714 km.
FlixBus operates a bus from Roma, Autostazione Tiburtina to Messina 3 times a day. Tickets cost €45–85 and the journey takes 9h 30m. Autoservizi Salemi Srl also services this route once daily.