The average bus between Chicago and Santa Ana takes 2d 19h and the fastest bus takes 2d 12h. The bus runs, on average, 5 times per week from Chicago to Santa Ana. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a week between Chicago and Santa Ana. The earliest departure is at 12:15 AM at night, and the last departure from Chicago is at 5:15 PM which arrives into Santa Ana at 3:30 AM. All services require a transfer at St Louis Bus Station and take an average of 2d 19h. The schedules shown below are for the next available departures.
Want to know about travelling from Chicago to Santa Ana? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Chicago to Santa Ana. However, there are services departing from Chicago station and arriving at Santa Ana station via St Louis Bus Station station. The journey, including transfers, takes approximately 2d 19h.
Chicago to Santa Ana bus services, operated by Flixbus USA, depart from Chicago Bus Station.
Chicago to Santa Ana bus services, operated by Flixbus USA, arrive at Santa Ana station.
Book your Chicago to Santa Ana bus tickets online with Flixbus USA, Greyhound USA and Amtrak.
The distance between Chicago and Santa Ana is 2,789.1 km. The road distance is 3,634 km.
You can take a bus from Chicago Bus Station to Santa Ana via St Louis Bus Station, Los Angeles Union Station, and Los Angeles in around 2d 1h.