The bus between Chicago and Des Moines takes 8h 25m. There is at least one bus per day from Chicago to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Chicago and Des Moines. The earliest departure is at 6:10 AM in the morning, and the last departure from Chicago is at 6:10 AM which arrives into Des Moines at 2:35 PM. All services run direct with no transfers required, and take on average 8h 25m. The schedules shown below are for the next available departures.
Want to know about travelling from Chicago to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Chicago station and arriving at Des Moines station. Services depart once daily, and operate Once daily. The journey takes approximately 8h 25m.
Chicago to Des Moines bus services, operated by Greyhound USA, depart from Chicago Bus Station.
Chicago to Des Moines bus services, operated by Greyhound USA, arrive at Des Moines station.
Book your Chicago to Des Moines bus tickets online with Greyhound USA.
The distance between Chicago and Des Moines is 497.1 km. The road distance is 554 km.
Greyhound USA operates a bus from Chicago Bus Station to Des Moines once daily. Tickets cost $60–110 and the journey takes 8h 25m.