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How to get fromChicago to Des Moinesby plane, bus or car

Find Transport to Des Moines

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There are 4 ways to get from Chicago to Des Moines by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Chicago O'Hare International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)plane plane ORD - DSM
    3h 19m
    $96–558
  2. Drive 330 mi

    cheapest
    1. Drive from Chicago to Des Moinescar car 330 mi
    5h 32m
    $61–87
  3. Bus

    1. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0155S
    8h 25m
  4. Fly from Chicago Midway International Airport

    1. Fly from Chicago Midway International Airport (MDW) to Des Moines (DSM)plane plane MDW - DSM
    3h 3m
    $131–793

Chicago O'Hare International Airport (ORD) to Des Moines (DSM) flights

Calendar91Weekly Planes
Duration1h 32mAverage Duration
Ticket$79Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Des Moines, IA, USA?

American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM) hourly. Alternatively, Greyhound-us operates a bus from Chicago Bus Station to Des Moines once daily, and the journey takes 8h 25m.

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