What is the cheapest way to get from Chicago to Des Moines?

The cheapest way to get from Chicago to Des Moines is to bus which costs $40 - $110 and takes 6h 34m.

What is the fastest way to get from Chicago to Des Moines?

The fastest way to get from Chicago to Des Moines is to fly which takes 3h 8m and costs $120 - $750.

Is there a direct bus between Chicago and Des Moines?

Yes, there is a direct bus departing from Chicago Bus Station station and arriving at Des Moines. Services depart three times a day, and operate every day. The journey takes approximately 6h 34m.

How far is it from Chicago to Des Moines?

The distance between Chicago and Des Moines is 324 miles. The road distance is 332 miles.

How do I travel from Chicago to Des Moines without a car?

The best way to get from Chicago to Des Moines without a car is to bus which takes 6h 34m and costs $40 - $110.

How long does it take to get from Chicago to Des Moines?

It takes approximately 3h 23m to get from Chicago to Des Moines, including transfers.

Where do I catch the Chicago to Des Moines bus from?

Chicago to Des Moines bus services, operated by Greyhound USA, depart from Chicago Bus Station.

Bus or fly from Chicago to Des Moines?

The best way to get from Chicago to Des Moines is to fly which takes 3h 23m and costs $95 - $600. Alternatively, you can bus, which costs $40 - $110 and takes 6h 34m.

Where does the Chicago to Des Moines bus arrive?

Chicago to Des Moines bus services, operated by Greyhound USA, arrive at Des Moines station.

Can I drive from Chicago to Des Moines?

Yes, the driving distance between Chicago to Des Moines is 332 miles. It takes approximately 5h 32m to drive from Chicago to Des Moines.

How do I get a bus ticket from Chicago to Des Moines?

Book your Chicago to Des Moines bus tickets online with Omio and FlixBus.

Where can I stay near Des Moines?

There are 245+ hotels available in Des Moines.

Chicago to Des Moines - 4 ways to travel via plane, bus, and car

There are 4 ways to get from Chicago to Des Moines by plane, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly from Chicago O'Hare International Airport
best
1. Fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM)plane ORD - DSM
3h 23m
$100–576
Bus (Greyhound)
cheapest
1. Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123 / ...
6h 34m
$40–110
Drive 330 mi
1. Drive from Chicago to Des Moinescar 330 mi
5h 32m
$61–87
Fly from Chicago Midway International Airport
1. Fly from Chicago Midway International Airport (MDW) to Des Moines (DSM)plane MDW - DSM
3h 8m
$120–726

Chicago to Des Moines by bus (Greyhound)

19Weekly Buses

6h 34mAverage Duration

$40Cheapest Price

See schedules

Questions & Answers

Map of how to get from Chicago to Des Moines.

Launch map view

Distance: 321.9 mi
Duration: 3h 23m

What companies run services between Chicago, IL, USA and Des Moines, IA, USA?

American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Des Moines (DSM) every 4 hours. Alternatively, Greyhound USA operates a bus from Chicago Bus Station to Des Moines 3 times a day. Tickets cost $40–110 and the journey takes 6h 34m.

Airlines

Bus operators

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