Rome2Rio

How to get fromHigh Point to St. Louisby plane, bus (Greyhound), train, bus, car, or train (Amtrak)

Find Transport to St. Louis

See all options

There are 8 ways to get from High Point to St. Louis by plane, bus (Greyhound), train, bus, car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Piedmont Triad International Airport

    best
    1. Fly from Piedmont Triad International Airport (GSO) to Lambert–St. Louis International Airport (STL)plane plane GSO - STL
    6h 8m
    $144–728

  2. Bus via Charleston

    cheapest
    1. Take the bus from Winston Salem(Trans Center) to Charleston, WVbus bus
    2. Take the bus from Charleston, WV to Cambridgebus bus
    3. Take the bus from Cambridge, OH to St Louis Bus Stationbus bus
    21h 13m
    $110–264

  3. Train, bus

    1. Take the train from High Point to Charlottesvilletrain train
    2. Take the train from Charlottesville to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    25h 11m
    $244–539

  4. Drive  698.8 mi

    1. Drive from High Point to St. Louiscar car 698.8 mi
    12h 45m
    $128–185

  5. Train to Charlotte Douglas International Airport, fly

    1. Take the train from High Point to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL)plane plane CLT - STL
    6h 5m
    $124–604

  6. Train to Raleigh-Durham International Airport, fly

    1. Take the train from High Point to Durham Amtrak Stationtrain train
    2. Fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL)plane plane RDU - STL
    6h 30m
    $575–1,150

  7. Bus

    1. Take the bus from High Point to Winston-Salembus bus
    2. Take the bus from Winston Salem to Columbusbus bus
    3. Take the bus from Columbus to St Louis Bus Stationbus bus
    21h 20m
    $112–230

  8. Train (Amtrak)

    1. Take the train from High Point to Carytrain train
    2. Take the train from Cary to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    33h 44m
    $373–871

High Point to St. Louis by bus

Calendar7Weekly Buses
Duration21h 13mAverage Duration
Ticket$110Cheapest Price
See schedules

Questions & Answers

Map of how to get from High Point to St. Louis.ExpandLaunch map view
  • Distance: 629.8 mi
  • Duration: 6h 8m

What companies run services between High Point, NC, USA and St. Louis, MO, USA?

Delta, American Airlines, and United Airlines fly from Piedmont Triad International Airport (GSO) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a bus from High Point Terminal to St Louis Bus Station via Winston-Salem Transportation Center, Winston Salem(Trans Center), Charleston, WV, Cambridge, and Cambridge, OH in around 21h 13m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers