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How to get fromHigh Point to St. Louisby plane, bus (Greyhound, Flixbus), train, bus, car, bus (Greyhound), or train (Amtrak)

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There are 9 ways to get from High Point to St. Louis by plane, bus (Greyhound, Flixbus), train, bus, car, bus (Greyhound), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Piedmont Triad International Airport

    best
    1. Fly from Piedmont Triad International Airport (GSO) to Lambert–St. Louis International Airport (STL)plane plane GSO - STL
    6h 14m
    $134–678

  2. Bus via Columbus

    cheapest
    1. Take the bus from High Point to Winston-Salembus bus
    2. Take the bus from Winston Salem to Columbusbus bus
    3. Take the bus from Columbus to St Louis Bus Stationbus bus
    21h 20m
    $112–210

  3. Bus

    1. Take the bus from Greensboro Bus Stop to Atlanta Bus Stationbus bus Greyhound US0670
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    21h 11m
    $132–238

  4. Train, bus

    1. Take the train from High Point to Charlottesvilletrain train
    2. Take the train from Charlottesville to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    25h 11m
    $468–774

  5. Drive  698.9 mi

    1. Drive from High Point to St. Louiscar car 698.9 mi
    12h 46m
    $128–185

  6. Train to Charlotte Douglas International Airport, fly

    1. Take the train from High Point to Charlotte Amtrak Stationtrain train
    2. Fly from Charlotte Douglas International Airport (CLT) to Lambert–St. Louis International Airport (STL)plane plane CLT - STL
    6h
    $141–624

  7. Train to Raleigh-Durham International Airport, fly

    1. Take the train from High Point to Durham Amtrak Stationtrain train
    2. Fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL)plane plane RDU - STL
    6h 40m
    $596–1,168

  8. Bus to Fayetteville Municipal Airport, fly

    1. Take the bus from High Point to Fayettevillebus bus
    2. Fly from Fayetteville Municipal Airport (FAY) to Lambert–St. Louis International Airport (STL)plane plane FAY - STL
    8h 36m
    $132–601

  9. Train (Amtrak)

    1. Take the train from High Point to Carytrain train
    2. Take the train from Cary to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    33h 44m
    $749–1,264

High Point to St. Louis by train and bus

Calendar3Weekly Services
Duration25h 11mAverage Duration
Ticket$468Cheapest Price
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Comparing Your Travel Options

Map of how to get from High Point to St. Louis.ExpandLaunch map view
  • Distance: 629.8 mi
  • Duration: 6h 14m

What companies run services between High Point, NC, USA and St. Louis, MO, USA?

Delta, American Airlines, and United Airlines fly from Piedmont Triad International Airport (GSO) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a bus from High Point Terminal to St Louis Bus Station via Greensboro Depot, Greensboro Bus Stop, and Atlanta Bus Station in around 21h 11m.

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Want to know more about travelling around United States

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