There are 9 ways to get from Wisconsin to Louisville by bus (Greyhound, Flixbus, Amtrak), train, bus, car, plane, or bus (Greyhound, Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Milwaukee Intermodal Station to Chicago Bus StationGreyhound US0150S / ...
- Take the bus from Chicago Union Station to Louisville, KYChicago
9h 54m$71–127Drive 382.4 mi
cheapest- Drive from Milwaukee to Louisville382.4 mi
6h 39m$70–101Train, bus (Amtrak)
- Take the train from Milwaukee to Chicago Union Station
- Take the train from Chicago Union Station to Indianapolis
- Take the bus from Indianapolis Union Station to Louisville, KY
10h 48m$74–161Fly General Mitchell International Airport to Louisville International Airport
- Fly from General Mitchell International Airport (MKE) to Louisville International Airport (SDF)MKE - SDF
6h 17m$113–705Bus via Indianapolis
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Take the bus from Chicago Bus Station to Indianapolis Union Station
- Take the bus from Indianapolis Union Station to Louisville, KY
10h 10m$94–183Bus to Chicago O'Hare International Airport, fly to Louisville International Airport
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)ORD - SDF
5h 29m$236–591Train to Chicago Midway International Airport, fly to Louisville International Airport
- Take the train from Kenosha to Chicago OTC
- Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)MDW - SDF
6h 2m$77–475Bus to Chicago O'Hare International Airport, fly to Blue Grass Airport, drive
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)ORD - LEX
- Drive from Lexington-Airport-LEX to Louisville
5h 33m$148–707Bus to Minneapolis–Saint Paul International Airport, fly to Louisville International Airport
- Take the bus from Eau Claire Amtrak Bus Stop to Mall of America - IKEA - Bloomington
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Louisville International Airport (SDF)MSP - SDF
6h 41m$329–591
Wisconsin to Louisville by bus and foot
Questions & Answers
The cheapest way to get from Wisconsin to Louisville is to drive which costs $70 - $110 and takes 6h 39m.
The fastest way to get from Wisconsin to Louisville is to bus and fly which takes 5h 29m and costs $230 - $600.
No, there is no direct bus from Wisconsin station to Louisville. However, there are services departing from Milwaukee Intermodal Station and arriving at Louisville, KY via Chicago Union Station. The journey, including transfers, takes approximately 9h 54m.
The distance between Wisconsin and Louisville is 386 miles. The road distance is 384.6 miles.
The best way to get from Wisconsin to Louisville without a car is to bus which takes 9h 54m and costs $70 - $130.
It takes approximately 9h 54m to get from Wisconsin to Louisville, including transfers.
Wisconsin to Louisville bus services, operated by Greyhound USA, depart from Milwaukee Intermodal Station.
The best way to get from Wisconsin to Louisville is to bus which takes 9h 54m and costs $70 - $130. Alternatively, you can fly, which costs $110 - $750 and takes 6h 17m.
Wisconsin to Louisville bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Louisville is 1h ahead of Wisconsin. It is currently 5:17 PM in Wisconsin and 6:17 PM in Louisville.
What companies run services between Wisconsin, USA and Louisville, KY, USA?
You can take a bus from Milwaukee Intermodal Station to Louisville, KY via Chicago Bus Station and Chicago Union Station in around 9h 54m. Alternatively, American Airlines, Delta, and two other airlines fly from General Mitchell International Airport (MKE) to Louisville International Airport (SDF) hourly.
- Website
- united.com
Flights from General Mitchell International Airport to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $110–700
Flights from Chicago O'Hare International Airport to Louisville International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $60–380
Flights from Chicago O'Hare International Airport to Blue Grass Airport
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $100–650
Flights from Minneapolis–Saint Paul International Airport to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $110–650
- Website
- aa.com
Flights from General Mitchell International Airport to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $110–700
Flights from General Mitchell International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Chicago O'Hare International Airport to Louisville International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $60–380
Flights from Chicago O'Hare International Airport to Blue Grass Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $100–650
Flights from Minneapolis–Saint Paul International Airport to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 41m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–650
- Website
- southwest.com
Flights from General Mitchell International Airport to Louisville International Airport via Baltimore
- Ave. Duration
- 5h 1m
- When
- Wednesday, Thursday, and Saturday
- Estimated price
- $210–1,100
Flights from General Mitchell International Airport to Louisville International Airport via Chicago Midway International Airport
- Ave. Duration
- 4h 55m
- When
- Monday and Friday
- Estimated price
- $110–700
Flights from General Mitchell International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 5h 5m
- When
- Saturday
- Estimated price
- $150–850
Flights from Chicago O'Hare International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 3h 40m
- When
- Monday, Tuesday, Friday, and Sunday
- Estimated price
- $80–440
Flights from Chicago Midway International Airport to Louisville International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $70–460
Flights from Minneapolis–Saint Paul International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 3h 55m
- When
- Monday, Tuesday, Friday, and Sunday
- Estimated price
- $140–750
Flights from Minneapolis–Saint Paul International Airport to Louisville International Airport via Chicago Midway International Airport
- Ave. Duration
- 4h 37m
- When
- Wednesday and Thursday
- Estimated price
- $110–650
- Website
- delta.com
Flights from General Mitchell International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $140–800
Flights from General Mitchell International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $200–1,000
Flights from General Mitchell International Airport to Louisville International Airport via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 5h 59m
- When
- Every day
- Estimated price
- $180–950
Flights from Minneapolis–Saint Paul International Airport to Louisville International Airport
- Ave. Duration
- 2h 11m
- When
- Every day
- Estimated price
- $110–650
Flights from Minneapolis–Saint Paul International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $180–850
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $30–75
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 312-322-6777
- Website
- metra.com
Train from Kenosha to Chicago OTC
- Ave. Duration
- 1h 42m
- Frequency
- Every 3 hours
- Estimated price
- $3–7
- Website
- https://metra.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $20–70
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Indianapolis Union Station
- Ave. Duration
- 3h 5m
- Frequency
- 5 times a day
- Estimated price
- $35–95
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Chicago Union Station to Louisville, KY
- Ave. Duration
- 7h
- Frequency
- Twice daily
- Estimated price
- $50–60
- Website
- https://www.amtrak.com/home.html
- Adult
- $50–60
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
- Phone
- (866) 912 6224
- questions@coachusa.com
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Every 2 hours
- Estimated price
- $35–38
- Schedules at
- coachusa.com
- Phone
- +1 414-266-4409
- ticketinfo@badgerbus.com
- Website
- badgerbus.com
Bus from Eau Claire Amtrak Bus Stop to Mall of America - IKEA - Bloomington
- Ave. Duration
- 1h 50m
- Frequency
- Twice a week
- Estimated price
- $26–35
- Website
- https://badgerbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Yes, the driving distance between Wisconsin to Louisville is 385 miles. It takes approximately 6h 39m to drive from Wisconsin to Louisville.
Book your Wisconsin to Louisville bus tickets online with Omio.
There are 572+ hotels available in Louisville.












