There are 9 ways to get from Wisconsin to Louisville by bus (Greyhound, Flixbus, Amtrak), train, bus, car, plane, or bus (Flixbus, Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus Greyhound US0150
- Take the bus from Chicago Union Station to Louisville, KYbus Chicago
9h 29m$64–84Train, bus (Amtrak)
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Indianapolistrain
- Take the bus from Indianapolis Union Station to Louisville, KYbus
10h 18m$169–287Drive 382.5 mi
- Drive from Milwaukee to Louisvillecar 382.5 mi
6h 44m$68–98Fly General Mitchell International Airport to Louisville International Airport
- Fly from General Mitchell International Airport (MKE) to Louisville International Airport (SDF)plane MKE - SDF
5h 46m$133–855Bus via Airport
- Take the bus from Milwaukee Mitchell Airport to Chicago Bus Stationbus FlixBus 2548 / ...
- Take the bus from Chicago Union Station to Louisville, KYbus Chicago
11h 16m$65–82Bus to Chicago O'Hare International Airport, fly to Louisville International Airport
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 1 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane ORD - SDF
5h 36m$114–534Bus to Chicago O'Hare International Airport, fly to Blue Grass Airport, drive
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 1 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane ORD - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
5h 38m$90–330Train to Chicago Midway International Airport, fly to Louisville International Airport
- Take the train from Kenosha to Chicago OTCtrain
- Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane MDW - SDF
6h 7m$130–816Bus to Minneapolis–Saint Paul International Airport, fly to Louisville International Airport
- Take the bus from Eau Claire Amtrak Bus Stop to Mall of America - IKEA - Bloomingtonbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Louisville International Airport (SDF)plane MSP - SDF
6h 20m$180–943
Wisconsin to Louisville by bus and foot
Comparing Your Travel Options
The cheapest way to get from Wisconsin to Louisville is to bus via Airport which costs $65 - $85 and takes 11h 16m.
The fastest way to get from Wisconsin to Louisville is to bus and fly which takes 5h 36m and costs $110 - $550.
No, there is no direct bus from Wisconsin station to Louisville. However, there are services departing from Milwaukee Intermodal Station and arriving at Louisville, KY via Chicago Union Station. The journey, including transfers, takes approximately 9h 29m.
The distance between Wisconsin and Louisville is 390 miles. The road distance is 384.7 miles.
The best way to get from Wisconsin to Louisville without a car is to bus which takes 9h 29m and costs $60 - $85.
It takes approximately 9h 29m to get from Wisconsin to Louisville, including transfers.
Wisconsin to Louisville bus services, operated by Greyhound USA, depart from Milwaukee Intermodal Station.
The best way to get from Wisconsin to Louisville is to bus which takes 9h 29m and costs $60 - $85. Alternatively, you can fly, which costs $130 - $900 and takes 5h 46m.
Wisconsin to Louisville bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Louisville is 1h ahead of Wisconsin. It is currently 3:07 PM in Wisconsin and 4:07 PM in Louisville.
What companies run services between Wisconsin, USA and Louisville, KY, USA?
You can take a bus from Milwaukee Intermodal Station to Louisville, KY via Chicago Bus Station and Chicago Union Station in around 9h 29m. Alternatively, Southwest Airlines, United Airlines, and two other airlines fly from General Mitchell International Airport (MKE) to Louisville International Airport (SDF) hourly.
- Website
- southwest.com
Flights from General Mitchell International Airport to Louisville International Airport via Chicago Midway International Airport
- Ave. Duration
- 3h 23m
- When
- Every day
- Estimated price
- $130–850
Flights from General Mitchell International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 3h 45m
- When
- Saturday
- Estimated price
- $170–1,000
Flights from General Mitchell International Airport to Louisville International Airport via Baltimore
- Ave. Duration
- 4h 50m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $250–1,200
Flights from Chicago Midway International Airport to Louisville International Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- $120–800
Flights from Minneapolis–Saint Paul International Airport to Louisville International Airport via Chicago Midway International Airport
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $160–900
Flights from Minneapolis–Saint Paul International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 4h 50m
- When
- Saturday
- Estimated price
- $190–1,000
- Website
- united.com
Flights from General Mitchell International Airport to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $130–850
Flights from Chicago O'Hare International Airport to Louisville International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $75–490
Flights from Chicago O'Hare International Airport to Blue Grass Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $40–270
Flights from Minneapolis–Saint Paul International Airport to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $160–900
- Website
- delta.com
Flights from General Mitchell International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 3h 49m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–950
Flights from General Mitchell International Airport to Louisville International Airport via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $210–1,100
Flights from General Mitchell International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $220–1,200
Flights from Minneapolis–Saint Paul International Airport to Louisville International Airport
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- $150–900
Flights from Minneapolis–Saint Paul International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 4h 22m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $180–1,000
Flights from Minneapolis–Saint Paul International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 50m
- When
- Sunday
- Estimated price
- $240–1,200
- Website
- aa.com
Flights from General Mitchell International Airport to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $130–850
Flights from General Mitchell International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 5h 3m
- When
- Monday to Wednesday
- Estimated price
- $220–1,200
Flights from Chicago O'Hare International Airport to Louisville International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $75–490
Flights from Chicago O'Hare International Airport to Blue Grass Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $40–270
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $100–170
- Website
- Amtrak
- Phone
- +1 312-696-3872
- Website
- Metra
Train from Kenosha to Chicago OTC
- Ave. Duration
- 1h 42m
- Frequency
- Every 3 hours
- Estimated price
- $6–8
- Website
- Metra
- Adult
- $6–8
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Estimated price
- $16–25
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 5 times a day
- Estimated price
- $14–21
- Schedules at
- Flixbus USA
Bus from Milwaukee Mitchell Airport to Chicago Bus Station
- Ave. Duration
- 1h 55m
- Frequency
- 5 times a day
- Estimated price
- $13–20
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Chicago Union Station to Louisville, KY
- Ave. Duration
- 6h 45m
- Frequency
- Twice daily
- Estimated price
- $50–60
- Website
- Amtrak
- Adult
- $50–60
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Chicago Union Station to Louisville, KY
- Ave. Duration
- 6h 45m
- Frequency
- Twice daily
- Estimated price
- $50–60
- Website
- Amtrak
- Adult
- $50–60
- Phone
- (866) 912 6224
- questions@coachusa.com
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 1 Departures
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 1 Departures
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- coachusa.com
- Phone
- +1 414-266-4409
- ticketinfo@badgerbus.com
- Website
- Badger Bus
Bus from Eau Claire Amtrak Bus Stop to Mall of America - IKEA - Bloomington
- Ave. Duration
- 1h 50m
- Frequency
- Twice a week
- Estimated price
- $26–35
- Website
- Badger Bus
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between Wisconsin to Louisville is 385 miles. It takes approximately 6h 44m to drive from Wisconsin to Louisville.
Book your Wisconsin to Louisville bus tickets online with Omio.
There are 29+ hotels available in Louisville.











