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How to get fromSt. Louis to Floridaby plane, bus (Greyhound, Flixbus), car, or bus

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There are 10 ways to get from St. Louis to Florida by plane, bus (Greyhound, Flixbus), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Jacksonville

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Jacksonville (JAX)plane plane STL - JAX
    5h 4m
    $134–706

  2. Fly to Northwest Florida Beaches International Airport, drive

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Northwest Florida Beaches International Airport (ECP)plane plane STL - ECP
    2. Drive from Northwest Florida Beaches International Airport (ECP) to Tallahasseecar car
    5h 34m
    $120–580

  3. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus Greyhound US0186
    2. Take the bus from Atlanta Bus Station to Jacksonvillebus bus FlixBus N2434 / ...
    19h 35m
    $125–267

  4. Drive 859.6 mi

    1. Drive from St. Louis to Jacksonvillecar car 859.6 mi
    15h 10m
    $157–227

  5. Fly to Fort Lauderdale–Hollywood International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane STL - FLL
    4h 57m
    $144–656

  6. Fly to Miami International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Miami International Airport (MIA)plane plane STL - MIA
    4h 46m
    $126–556

  7. Fly to Tampa

    1. Fly from Lambert–St. Louis International Airport (STL) to Tampa (TPA)plane plane STL - TPA
    5h 12m
    $124–604

  8. Fly to Orlando

    1. Fly from Lambert–St. Louis International Airport (STL) to Orlando (MCO)plane plane STL - MCO
    5h 15m
    $246–858

  9. Fly to Ft. Myers

    1. Fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW)plane plane STL - RSW
    6h 20m
    $136–658

  10. Fly to Sarasota–Bradenton International Airport, line 203 bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Sarasota–Bradenton International Airport (SRQ)plane plane STL - SRQ
    2. Take the bus from Downtown Station to 34Th St S Nb/1St Av Sbus bus
    6h 44m
    $154–762

St. Louis to Florida by bus

Calendar12Weekly Buses
Duration19h 35mAverage Duration
Ticket$125Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Florida.ExpandLaunch map view
  • Distance: 785.1 mi
  • Duration: 5h 4m

What companies run services between St. Louis, MO, USA and Florida, USA?

Southwest Airlines, Delta, and American Airlines fly from Lambert–St. Louis International Airport (STL) to Jacksonville (JAX) every 4 hours. Alternatively, you can take a bus from St Louis Bus Station to Jacksonville via Atlanta Bus Station in around 19h 35m.

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