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How to get fromSikeston to Mobileby car, plane, train, taxi, or bus

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There are 5 ways to get from Sikeston to Mobile by car, plane, train, taxi, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, fly

    best
    1. Drive from Sikeston to Barkley Regional Airport (PAH)car car
    2. Fly from Barkley Regional Airport (PAH) to Mobile Regional Airport (MOB)plane plane PAH - MOB
    8h 50m
    $130–515

  2. Drive  499.5 mi

    cheapest
    1. Drive from Sikeston to Mobilecar car 499.5 mi
    9h 34m
    $92–132

  3. Drive, train (Amtrak)

    1. Drive from Sikeston to Fulton Amtrak Stationcar car
    2. Take the train from Fulton Amtrak Station to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    17h 4m
    $333–588

  4. Taxi, bus, train

    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train
    18h 53m
    $224–391

  5. Taxi, bus

    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to New Orleans Bus Stationbus bus
    3. Take the bus from New Orleans Bus Station to Mobile Bus Stationbus bus
    19h 46m
    $215–311

Barkley Regional Airport (PAH) to Mobile Regional Airport (MOB) flights

Calendar6Weekly Planes
Duration7h 15mAverage Duration
Ticket$94Cheapest Price
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Comparing Your Travel Options

Map of how to get from Sikeston to Mobile.ExpandLaunch map view
  • Distance: 510.5 mi
  • Duration: 8h 50m

What companies run services between Sikeston, MO, USA and Mobile, AL, USA?

There is no direct connection from Sikeston to Mobile. However, you can drive to Barkley Regional Airport (PAH) airport, fly to Mobile Regional Airport (MOB), then take the taxi to Mobile. Alternatively, you can take a vehicle from Sikeston to Mobile Amtrak Sta via Fulton Amtrak Station and New Orleans Union Passenger Terminal in around 17h 4m.

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