There are 9 ways to get from Sikeston to Mobile by taxi, plane, bus, car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Cape Girardeau Municipal Airport, fly to Pensacola International Airport, bus
best- Take the taxi from Sikeston to Cape Girardeau Municipal Airport (CGI)taxi
- Fly from Cape Girardeau Municipal Airport (CGI) to Pensacola International Airport (PNS)plane CGI - PNS
- Take the bus from Pensacola Airport to Mobile Bus Stationbus
6h 6m$284–531Drive 499.5 mi
cheapest- Drive from Sikeston to Mobilecar 499.5 mi
9h 44m$92–132Drive, train, bus
- Drive from Sikeston to Fulton Amtrak Stationcar
- Take the train from Fulton Amtrak Station to New Orleans Union Passenger Terminaltrain
- Take the bus from New Orleans Bus Station to Mobile Bus Stationbus
18h 55m$181–398Taxi, bus
- Take the taxi from Sikeston to Cape Girardeautaxi
- Take the bus from Cape Girardeau to New Orleans Bus Stationbus
- Take the bus from New Orleans Bus Station to Mobile Bus Stationbus
20h 4m$212–361Taxi to Cape Girardeau Municipal Airport, fly to Mobile Regional Airport
- Take the taxi from Sikeston to Cape Girardeau Municipal Airport (CGI)taxi
- Fly from Cape Girardeau Municipal Airport (CGI) to Mobile Regional Airport (MOB)plane CGI - MOB
11h 11m$204–750Bus to Memphis, fly to Pensacola International Airport, bus
- Take the bus from Flying J - Matthews to Tornado Bus Co - West Memphisbus
- Fly from Memphis (MEM) to Pensacola International Airport (PNS)plane MEM - PNS
- Take the bus from Pensacola Airport to Mobile Bus Stationbus
10h 29m$189–675Drive, bus to Nashville, fly to Destin–Fort Walton Beach Airport, bus
- Drive from Sikeston to Paducah Bus Stationcar
- Take the bus from Paducah Bus Station to Nashville Bus Stationbus
- Fly from Nashville (BNA) to Destin–Fort Walton Beach Airport (VPS)plane BNA - VPS
- Take the bus from McDonald's - Crestview to Love's Travel Stop - Loxleybus
9h 51m$221–639Drive, bus to Nashville, fly to Pensacola International Airport, bus
- Drive from Sikeston to Paducah Bus Stationcar
- Take the bus from Paducah Bus Station to Nashville Bus Stationbus
- Fly from Nashville (BNA) to Pensacola International Airport (PNS)plane BNA - PNS
- Take the bus from Pensacola Airport to Mobile Bus Stationbus
10h 45m$151–460Taxi, bus to Midamerica St. Louis Airport, fly to Destin–Fort Walton Beach Airport, bus
- Take the taxi from Sikeston to Cape Girardeautaxi
- Take the bus from Cape Girardeau to St Louis Bus Stationbus
- Fly from Midamerica St. Louis Airport (BLV) to Destin–Fort Walton Beach Airport (VPS)plane BLV - VPS
- Take the bus from McDonald's - Crestview to Love's Travel Stop - Loxleybus
9h 6m$340–792
Cape Girardeau Municipal Airport (CGI) to Pensacola International Airport (PNS) flights
Questions & Answers
The cheapest way to get from Sikeston to Mobile is to drive which costs $90 - $140 and takes 9h 44m.
The fastest way to get from Sikeston to Mobile is to taxi and fly and bus which takes 6h 6m and costs $280 - $550.
The distance between Sikeston and Mobile is 590 miles. The road distance is 502.5 miles.
The best way to get from Sikeston to Mobile without a car is to taxi and bus which takes 20h 4m and costs $210 - $370.
It takes approximately 6h 6m to get from Sikeston to Mobile, including transfers.
Yes, the driving distance between Sikeston to Mobile is 502 miles. It takes approximately 9h 44m to drive from Sikeston to Mobile.
There are 199+ hotels available in Mobile.
What companies run services between Sikeston, MO, USA and Mobile, AL, USA?
There is no direct connection from Sikeston to Mobile. However, you can take the taxi to Cape Girardeau Municipal Airport (CGI) airport, fly to Pensacola International Airport (PNS), walk to Pensacola Airport, take the bus to Mobile Bus Station, walk to Govt EB at Greyhound Bus Station, then take the line 9 bus to Water NB at St Louis St. Alternatively, you can take a vehicle from Sikeston to Govt EB at Lawrence St via Fulton Amtrak Station, New Orleans Union Passenger Terminal, New Orleans Bus Station, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 18h 55m.
- Website
- delta.com
Flights from Cape Girardeau Municipal Airport to Mobile Regional Airport via Pensacola International Airport, Atlanta
- Ave. Duration
- 9h 38m
- When
- Wednesday
- Estimated price
- $260–1,100
Flights from Cape Girardeau Municipal Airport to Mobile Regional Airport via Chicago O'Hare, Atlanta
- Ave. Duration
- 13h 13m
- When
- Every day
- Estimated price
- $140–700
Flights from Memphis to Pensacola International Airport via Atlanta
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- $85–550
Flights from Nashville to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 3h 34m
- When
- Every day
- Estimated price
- $55–350
Flights from Nashville to Pensacola International Airport via Atlanta
- Ave. Duration
- 3h 34m
- When
- Every day
- Estimated price
- $60–380
- Website
- southwest.com
Flights from Nashville to Destin–Fort Walton Beach Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $50–330
Flights from Nashville to Pensacola International Airport
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $55–360
- Website
- aa.com
Flights from Cape Girardeau Municipal Airport to Mobile Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 29m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Cape Girardeau Municipal Airport to Mobile Regional Airport via Chicago O'Hare, Dallas/Ft.Worth
- Ave. Duration
- 9h 16m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $180–850
Flights from Cape Girardeau Municipal Airport to Mobile Regional Airport via Chicago O'Hare, Charlotte
- Ave. Duration
- 13h 6m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–800
- Website
- united.com
Flights from Cape Girardeau Municipal Airport to Mobile Regional Airport via Chicago O'Hare, Houston
- Ave. Duration
- 12h 14m
- When
- Every day
- Estimated price
- $180–850
Flights from Cape Girardeau Municipal Airport to Mobile Regional Airport via Pensacola International Airport, Houston
- Ave. Duration
- 13h 14m
- When
- Wednesday and Saturday
- Estimated price
- $150–750
- Website
- allegiantair.com
Flights from Midamerica St. Louis Airport to Destin–Fort Walton Beach Airport
- Ave. Duration
- 1h 43m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $60–350
- Website
- contouraviation.com
Flights from Cape Girardeau Municipal Airport to Pensacola International Airport
- Ave. Duration
- 1h 45m
- When
- Wednesday and Saturday
- Estimated price
- $190–410
- Website
- flybreeze.com
Flights from Memphis to Pensacola International Airport
- Ave. Duration
- 1h 26m
- When
- Monday and Friday
- Estimated price
- $80–180
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Fulton Amtrak Station to New Orleans Union Passenger Terminal
- Ave. Duration
- 12h 33m
- Frequency
- Once daily
- Estimated price
- $150–330
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Pensacola Airport to Mobile Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $10–21
- Website
- https://www.greyhound.com/
Bus from New Orleans Bus Station to Mobile Bus Station
- Ave. Duration
- 2h 20m
- Frequency
- 3 times a day
- Estimated price
- $25–50
- Website
- https://www.greyhound.com/
Bus from Cape Girardeau to New Orleans Bus Station
- Ave. Duration
- 14h 35m
- Frequency
- Once daily
- Estimated price
- $100–200
- Website
- https://www.greyhound.com/
Bus from Cape Girardeau to St Louis Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from New Orleans Bus Station to Mobile Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- 6 times a week
- Estimated price
- $18–35
- Schedules at
- flixbus.com
Bus from Paducah Bus Station to Nashville Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $17–30
- Schedules at
- flixbus.com
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Flying J - Matthews to Tornado Bus Co - West Memphis
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $45–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $45–140
Bus from McDonald's - Crestview to Love's Travel Stop - Loxley
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $40–130
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–130
- Ave. Duration
- 34 min
- Estimated price
- $80–120
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