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How to get fromSiena to Avignonby bus, train, car, plane, train (Trenitalia, TGV) or ferry

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There are 10 ways to get from Siena to Avignon by bus, train, car, plane, train (Trenitalia, TGV), or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus bus 131
    2. Take the train from Firenze S.M.N. to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Lyon Part Dieutrain train Fr
    4. Take the train from Lyon Part Dieu to Avignon Tgvtrain train Tgv
    11h 24m
    €125–266

  2. Bus

    cheapest
    1. Take the bus from Siena to Florence Villa Constanza Bus Stationbus bus 443 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Marseille, Gare de Marseille-Saint-Charlesbus bus
    3. Take the bus from Marseille, Gare de Marseille-Saint-Charles to Avignonbus bus
    12h 45m
    €52–99

  3. Drive 712 km

    1. Drive from Siena to Avignoncar car 712 km
    7h 52m
    €110–159

  4. Bus to Florence Peretola Airport, fly to Marseille Provence Airport, train

    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus bus
    2. Fly from Florence Peretola Airport (FLR) to Marseille Provence Airport (MRS)plane plane FLR - MRS
    3. Take the train from Aix En Provence Tgv to Avignon Tgvtrain train
    8h 10m
    €103–297

  5. Train

    1. Take the train from Siena to Empolitrain train Re
    2. Take the train from Empoli to Pisa Centraletrain train Re
    3. Take the train from Pisa Centrale to Ventimigliatrain train Ic
    4. Take the train from Nice Ville to Avignon Tgvtrain train Tgv
    13h 23m
    €113–216

  6. Bus via Nice Airport (NCE)

    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus bus 131
    2. Take the bus from Florence to Nice Airportbus bus
    3. Take the bus from Nice - Airport Bus Station Terminal 1 to Avignon – Bus Stationbus bus
    14h 42m
    €55–101

  7. Bus, train to Bologna Guglielmo Marconi Airport, fly to Marseille Provence Airport, train

    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus bus
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Marseille Provence Airport (MRS)plane plane BLQ - MRS
    4. Take the train from Aix En Provence Tgv to Avignon Tgvtrain train
    6h 50m
    €65–315

  8. Bus, ferry to Bastia - Poretta Airport, fly to Marseille Provence Airport, train

    1. Take the bus from Colonna San Marco to Port of Piombinobus bus
    2. Take the ferry from Port of Piombino to Port of Bastiaferry ferry
    3. Fly from Bastia - Poretta Airport (BIA) to Marseille Provence Airport (MRS)plane plane BIA - MRS
    4. Take the train from Aix En Provence Tgv to Avignon Tgvtrain train
    10h 19m
    €143–417

  9. Bus to Florence Peretola Airport, fly to Nice Côte D'Azur International Airport, train

    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus bus
    2. Fly from Florence Peretola Airport (FLR) to Nice Côte D'Azur International Airport (NCE)plane plane FLR - NCE
    3. Take the train from Antibes to Avignon Tgvtrain train
    9h 48m
    €154–323

  10. Bus, train to Fiumicino International Airport, fly to Marseille Provence Airport, train

    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus bus
    2. Take the train from Firenze S.M.N. to Roma Terminitrain train
    3. Fly from Fiumicino International Airport (FCO) to Marseille Provence Airport (MRS)plane plane FCO - MRS
    4. Take the train from Aix En Provence Tgv to Avignon Tgvtrain train
    8h 24m
    €91–317

Siena to Avignon by bus and train

Calendar14Weekly Services
Duration11h 24mAverage Duration
Ticket€125Cheapest Price
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Questions & Answers

What companies run services between Siena, Italy and Avignon, France?

You can take a bus from Siena to Avignon via Florence Villa Constanza Bus Station and Marseille, Gare de Marseille-Saint-Charles in around 12h 45m. Alternatively, you can take a train from Siena to Avignon Tgv via Empoli, Pisa Centrale, Ventimiglia, and Nice Ville in around 13h 23m.

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