There are 9 ways to get from Siena to Avignon by train (TGV), bus, car, train, plane, or train (Trenitalia, TGV)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Siena to Firenze S.M.N.Re
- Take the train from Florence Santa Maria Novella to Milano Centrale
- Take the train from Milano Centrale to Lyon Part DieuFr
- Take the train from Lyon Part Dieu to Avignon TgvTgv
11h 56m€113–300Bus via Genoa
cheapest- Take the bus from Siena Central Train Station to Genoa Piazza della VittoriaItabus
- Take the bus from Genoa Piazza Acquaverde to Avignon Le Pontet Bus StationUnion Ivkoni - Unibus 3577 / ...
13h 15m€31–58Bus
- Take the bus from Siena to Florence Villa Constanza Bus Station443 / ...
- Take the bus from Florence Villa Constanza Bus Station to Marseille, Gare de Marseille-Saint-Charles
- Take the bus from Marseille, Gare de Marseille-Saint-Charles to Avignon
12h 45m€46–127Drive 711.1 km
- Drive from Siena to Avignon711.1 km
7h 47m€110–159Train to Florence Peretola Airport, fly to Marseille Provence Airport, train
- Take the train from Siena to Firenze S.M.N.
- Fly from Florence Peretola Airport (FLR) to Marseille Provence Airport (MRS)FLR - MRS
- Take the train from Aix En Provence Tgv to Avignon Tgv
9h 30m€101–297Train via Ventimiglia
- Take the train from Siena to EmpoliRe
- Take the train from Empoli to Pisa CentraleRe
- Take the train from Pisa Centrale to VentimigliaIc
- Take the train from Nice Ville to Avignon TgvTgv
12h 53m€93–151Train to Florence Peretola Airport, fly to Nice Côte D'Azur International Airport, train
- Take the train from Siena to Firenze S.M.N.
- Fly from Florence Peretola Airport (FLR) to Nice Côte D'Azur International Airport (NCE)FLR - NCE
- Take the train from Antibes to Avignon Tgv
9h 42m€130–263Train, train to Venice Marco Polo Airport, fly to Marseille Provence Airport
- Take the train from Siena to Firenze S.M.N.
- Take the train from Firenze S.M.N. to Venezia Mestre
- Fly from Venice Marco Polo Airport (VCE) to Marseille Provence Airport (MRS)VCE - MRS
- Take the train from Aix En Provence Tgv to Avignon Tgv
9h 39m€96–285Train, train to Roma Ciampino Airport, fly to Marseille Provence Airport
- Take the train from Siena to Firenze S.M.N.
- Take the train from Florence Santa Maria Novella to Roma Termini
- Fly from Roma Ciampino Airport (CIA) to Marseille Provence Airport (MRS)CIA - MRS
- Take the train from Aix En Provence Tgv to Avignon Tgv
9h 6m€85–311
Siena to Avignon by train
Questions & Answers
The cheapest way to get from Siena to Avignon is to bus via Genoa which costs €30 - €60 and takes 13h 15m.
The fastest way to get from Siena to Avignon is to drive which takes 7h 47m and costs €110 - €160.
No, there is no direct bus from Siena to Avignon. However, there are services departing from Siena and arriving at Avignon via Florence Villa Constanza Bus Station and Marseille, Gare de Marseille-Saint-Charles. The journey, including transfers, takes approximately 12h 45m.
No, there is no direct train from Siena to Avignon. However, there are services departing from Siena and arriving at Avignon Tgv via Florence Santa Maria Novella, Milano Centrale and Lyon Part Dieu. The journey, including transfers, takes approximately 11h 56m.
The distance between Siena and Avignon is 1068 km. The road distance is 711.1 km.
The best way to get from Siena to Avignon without a car is to train which takes 11h 56m and costs €110 - €300.
It takes approximately 11h 56m to get from Siena to Avignon, including transfers.
Siena to Avignon bus services, operated by FlixBus, depart from Siena station.
Siena to Avignon train services, operated by Trenitalia S.p.A., depart from Siena station.
The best way to get from Siena to Avignon is to train which takes 11h 56m and costs €110 - €300. Alternatively, you can bus, which costs €45 - €130 and takes 12h 45m.
What companies run services between Siena, Italy and Avignon, France?
You can take a train from Siena to Avignon Tgv via Florence Santa Maria Novella, Milano Centrale, and Lyon Part Dieu in around 11h 56m. Alternatively, you can take a bus from Siena to Avignon via Florence Villa Constanza Bus Station and Marseille, Gare de Marseille-Saint-Charles in around 12h 45m.
- Website
- ryanair.com
Flights from Florence Peretola Airport to Marseille Provence Airport via Rome
- Ave. Duration
- 6h 30m
- When
- Sunday
- Estimated price
- €100–250
Flights from Roma Ciampino Airport to Marseille Provence Airport
- Ave. Duration
- 1h 35m
- When
- Wednesday to Sunday
- Estimated price
- €45–200
- Website
- swiss.com
Flights from Florence Peretola Airport to Marseille Provence Airport via Zurich
- Ave. Duration
- 4h 20m
- When
- Monday, Wednesday, and Saturday
- Estimated price
- €95–390
Flights from Florence Peretola Airport to Nice Côte D'Azur International Airport via Zurich
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €80–330
Flights from Venice Marco Polo Airport to Marseille Provence Airport via Zurich
- Ave. Duration
- 4h 10m
- When
- Monday, Wednesday, and Saturday
- Estimated price
- €80–310
- Website
- lufthansa.com
Flights from Florence Peretola Airport to Marseille Provence Airport via Munich
- Ave. Duration
- 5h 31m
- When
- Every day
- Estimated price
- €75–250
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Nice Côte D'Azur International Airport
- Ave. Duration
- 1h 20m
- When
- Monday and Friday
- Estimated price
- €80–180
Flights from Florence Peretola Airport to Nice Côte D'Azur International Airport via Rome
- Ave. Duration
- 3h 35m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- €85–150
- Website
- aircorsica.com
Flights from Florence Peretola Airport to Nice Côte D'Azur International Airport
- Ave. Duration
- 1h 20m
- When
- Monday and Friday
- Estimated price
- €80–180
- Website
- volotea.com
Flights from Venice Marco Polo Airport to Marseille Provence Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €40–150
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €7–10
- Website
- https://www.trenitalia.com/en.html
Train from Milano Centrale to Lyon Part Dieu
- Ave. Duration
- 4h 39m
- Frequency
- Twice daily
- Estimated price
- €50–140
- Website
- https://www.trenitalia.com/en.html
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 21 min
- Frequency
- 4 times a day
- Estimated price
- €15–35
- Website
- https://www.trenitalia.com/en.html
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- €5–8
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–7
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €26–70
- Website
- https://www.italotreno.it/en
Train from Florence Santa Maria Novella to Roma Termini
- Ave. Duration
- 1h 32m
- Frequency
- Hourly
- Estimated price
- €23–55
- Website
- https://www.italotreno.it/en
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Lyon Part Dieu to Avignon Tgv
- Ave. Duration
- 1h 2m
- Frequency
- Every 3 hours
- Estimated price
- €30–80
- Website
- https://www.sncf-connect.com/en-en
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €15–35
- Website
- https://www.sncf-connect.com/en-en
Train from Nice Ville to Avignon Tgv
- Ave. Duration
- 2h 56m
- Frequency
- 4 times a day
- Estimated price
- €45–80
- Website
- https://www.sncf-connect.com/en-en
Train from Antibes to Avignon Tgv
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- €45–75
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Lyon Part Dieu to Avignon Tgv
- Ave. Duration
- 1h 4m
- Frequency
- Once daily
- Estimated price
- €40–55
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 20 min
- Frequency
- Every 4 hours
- Estimated price
- €12–27
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €12–18
- Rail 1st Class
- €19–27
- Phone
- +33 2 22 55 00 10
- nomad-car@laregionnormandie.fr
- Website
- nomad.normandie.fr
Train from Lyon Part Dieu to Avignon Tgv
- Ave. Duration
- 1h 12m
- Frequency
- 5 times a week
- Schedules at
- nomad.normandie.fr
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 19 min
- Frequency
- Twice daily
- Estimated price
- €7–10
- Website
- https://www.renfe.com/es/en
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 19 min
- Frequency
- 4 times a week
- Estimated price
- €27–30
- Website
- https://int.bahn.de/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to Ventimiglia
- Ave. Duration
- 4h 36m
- Frequency
- Once daily
- Estimated price
- €28–45
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Venezia Mestre
- Ave. Duration
- 2h 3m
- Frequency
- Hourly
- Estimated price
- €22–60
- Schedules at
- trenitalia.com
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Siena to Florence Villa Constanza Bus Station
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €11–18
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Marseille, Gare de Marseille-Saint-Charles
- Ave. Duration
- 8h 55m
- Frequency
- Twice daily
- Estimated price
- €30–90
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Siena to Florence Villa Constanza Bus Station
- Ave. Duration
- 55 min
- Frequency
- 4 times a day
- Estimated price
- €12–13
- Website
- https://www.itabus.it/en/home
Bus from Siena Central Train Station to Genoa Piazza della Vittoria
- Ave. Duration
- 4h 25m
- Frequency
- 3 times a week
- Estimated price
- €7–25
- Website
- https://www.itabus.it/en/home
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Siena to Florence Villa Constanza Bus Station
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- €7–10
- Website
- https://marinobus.it/en/
- Phone
- +34 910 207 007
- alsa@alsa.es
- Website
- alsa.com
Bus from Marseille, Gare de Marseille-Saint-Charles to Avignon
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- €9–20
- Website
- https://www.alsa.com/en/
- Phone
- 07001 8282
- booking@union-ivkoni.com
- Website
- union-ivkoni.com
Bus from Genoa Piazza Acquaverde to Avignon Le Pontet Bus Station
- Ave. Duration
- 7h 30m
- Frequency
- 3 times a week
- Estimated price
- €19–28
- Website
- https://union-ivkoni.com/en
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More Questions & Answers
Siena to Avignon bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Siena to Avignon train services, operated by Trenitalia S.p.A., arrive at Firenze S.M.N. station.
Yes, the driving distance between Siena to Avignon is 711 km. It takes approximately 7h 47m to drive from Siena to Avignon.
Book your Siena to Avignon train tickets online with Omio.
Book your Siena to Avignon bus tickets online with Omio.
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