There are 10 ways to get from Siena to Avignon by train (Trenitalia, TGV), bus, ferry, train, car, train (Trenitalia), or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Siena to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Bologna Centraletrain Fr
- Take the train from Bologna centrale to Milano Centraletrain
- Take the train from Milano Centrale to Lyon Part Dieutrain Fr
- Take the train from Lyon Part Dieu to Avignon Tgvtrain Tgv
11h 23m€123–275Bus
cheapest- Take the bus from Siena to Florence Villa Constanza Bus Stationbus 443 / ...
- Take the bus from Florence Villa Constanza Bus Station to Marseille, Gare de Marseille-Saint-Charlesbus
- Take the bus from Marseille - Saint-Charles Bus Station to Avignon - Le Pontet - Le Lac Stopbus
13h 22m€70–109Bus, ferry, train
- Take the bus from Siena-Via Tozzi to Port of Piombinobus
- Take the ferry from Port of Piombino to Port of Bastiaferry
- Take the ferry from Port of Bastia to Port of Toulonferry
- Take the train from Toulon to Marseille Saint-Charlestrain C6 / ...
- Take the train from Marseille Saint-Charles to Avignon Centretrain C7 / ...
23h 45m€125–196Drive 711.4 km
- Drive from Siena to Avignoncar 711.4 km
7h 54m€135–195Train via Ventimiglia
- Take the train from Siena to Empolitrain Re
- Take the train from Empoli to Pisa Centraletrain Re
- Take the train from Pisa Centrale to Ventimigliatrain Ic
- Take the train from Nice-Ville to Marseille-Saint-Charlestrain
- Take the train from Marseille Saint-Charles to Avignon Centretrain C7 / ...
14h 22m€136–215Train to Florence Peretola Airport, fly to Marseille Provence Airport, train
- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Marseille Provence Airport (MRS)plane FLR - MRS
- Take the train from Aix En Provence Tgv to Avignon Tgvtrain
8h 57m€109–273Bus, ferry to Bastia - Poretta Airport, fly to Marseille Provence Airport, train
- Take the bus from Colonna San Marco to Port of Piombinobus
- Take the ferry from Port of Piombino to Port of Bastiaferry
- Fly from Bastia - Poretta Airport (BIA) to Marseille Provence Airport (MRS)plane BIA - MRS
- Take the train from Aix En Provence Tgv to Avignon Tgvtrain
10h 46m€141–381Train, train to Fiumicino International Airport, fly to Marseille Provence Airport
- Take the train from Siena to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Marseille Provence Airport (MRS)plane FCO - MRS
- Take the train from Aix En Provence Tgv to Avignon Tgvtrain
8h 17m€103–297Train to Florence Peretola Airport, fly to Lyon–Saint Exupéry Airport, train
- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Lyon–Saint Exupéry Airport (LYS)plane FLR - LYS
- Take the train from Lyon-Saint Exupery Tgv to Avignon Tgvtrain
7h 7m€78–332Train, train to Roma Ciampino Airport, fly to Marseille Provence Airport
- Take the train from Siena to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Roma Terminitrain
- Fly from Roma Ciampino Airport (CIA) to Marseille Provence Airport (MRS)plane CIA - MRS
- Take the train from Aix En Provence Tgv to Avignon Tgvtrain
9h 9m€97–372
Siena to Avignon by bus
Comparing Your Travel Options
The cheapest way to get from Siena to Avignon is to bus which costs €70 - €110 and takes 13h 22m.
The fastest way to get from Siena to Avignon is to train and fly which takes 7h 7m and costs €75 - €340.
No, there is no direct bus from Siena to Avignon. However, there are services departing from Siena and arriving at Thiers via Florence Villa Constanza Bus Station, Marseille - Saint-Charles Bus Station and Le Lac. The journey, including transfers, takes approximately 13h 22m.
No, there is no direct train from Siena to Avignon. However, there are services departing from Siena and arriving at Avignon Tgv via Firenze S.M.N., Bologna centrale, Milano Centrale and Lyon Part Dieu. The journey, including transfers, takes approximately 11h 23m.
The distance between Siena and Avignon is 1068 km. The road distance is 711.4 km.
The best way to get from Siena to Avignon without a car is to train which takes 11h 23m and costs €120 - €280.
It takes approximately 11h 23m to get from Siena to Avignon, including transfers.
Siena to Avignon bus services, operated by FlixBus, depart from Siena station.
Siena to Avignon train services, operated by Trenitalia, depart from Siena station.
The best way to get from Siena to Avignon is to train which takes 11h 23m and costs €120 - €280. Alternatively, you can bus, which costs €70 - €110 and takes 13h 22m.
What companies run services between Siena, Italy and Avignon, France?
You can take a train from Siena to Avignon Tgv via Firenze S.M.N., Bologna centrale, Milano Centrale, and Lyon Part Dieu in around 11h 23m. Alternatively, you can take a bus from Siena to Thiers via Florence Villa Constanza Bus Station, Marseille - Saint-Charles Bus Station, and Le Lac in around 13h 22m.
- Website
- ryanair.com
Flights from Florence Peretola Airport to Marseille Provence Airport via Fiumicino International Airport
- Ave. Duration
- 4h 5m
- When
- Friday
- Estimated price
- €75–230
Flights from Fiumicino International Airport to Marseille Provence Airport
- Ave. Duration
- 1h
- When
- Friday
- Estimated price
- €40–180
Flights from Roma Ciampino Airport to Marseille Provence Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €45–260
- Website
- aircorsica.com
Flights from Bastia - Poretta Airport to Marseille Provence Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- €70–340
Flights from Bastia - Poretta Airport to Marseille Provence Airport via Ajaccio
- Ave. Duration
- 2h 17m
- When
- Friday and Sunday
- Estimated price
- €70–340
Flights from Fiumicino International Airport to Marseille Provence Airport via Bastia - Poretta Airport
- Ave. Duration
- 2h 35m
- When
- Tuesday and Friday
- Estimated price
- €110–400
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Marseille Provence Airport via Fiumicino International Airport
- Ave. Duration
- 7h
- When
- Monday and Friday
- Estimated price
- €130–190
Flights from Fiumicino International Airport to Marseille Provence Airport
- Ave. Duration
- 1h 25m
- When
- Monday and Friday
- Estimated price
- €95–150
- Website
- swiss.com
Flights from Florence Peretola Airport to Marseille Provence Airport via Zurich
- Ave. Duration
- 3h 50m
- When
- Monday, Wednesday, and Saturday
- Estimated price
- €90–370
- Website
- volotea.com
Flights from Florence Peretola Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Monday and Friday
- Estimated price
- €24–190
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- Twice daily
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Milano Centrale to Lyon Part Dieu
- Ave. Duration
- 4h 43m
- Frequency
- Twice daily
- Estimated price
- €50–75
- Website
- Trenitalia
Train from Lyon Part Dieu to Avignon Tgv
- Ave. Duration
- 1h 9m
- Frequency
- Once daily
- Estimated price
- €27–40
- Website
- Trenitalia
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 22 min
- Frequency
- 4 times a day
- Estimated price
- €8–12
- Website
- Trenitalia
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 22 min
- Frequency
- 4 times a day
- Estimated price
- €8–12
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- 4 times a day
- Estimated price
- €30–45
- Website
- Trenitalia
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 22 min
- Frequency
- 4 times a day
- Estimated price
- €8–12
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Lyon-Saint Exupery Tgv to Avignon Tgv
- Ave. Duration
- 50 min
- Frequency
- 4 times a day
- Estimated price
- €25–35
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- 4 times a day
- Estimated price
- €30–45
- Website
- Trenitalia
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 22 min
- Frequency
- 4 times a day
- Estimated price
- €8–12
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Hourly
- Estimated price
- €12–21
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 36m
- Frequency
- Every 30 minutes
- Estimated price
- €35–60
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 36m
- Frequency
- Every 30 minutes
- Estimated price
- €35–60
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 45 min
- Frequency
- 4 times a day
- Estimated price
- €10–18
- Website
- Italo Treno
Train from Bologna centrale to Milano Centrale
- Ave. Duration
- 1h 4m
- Frequency
- Every 30 minutes
- Estimated price
- €25–45
- Website
- Italo Treno
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 47m
- Frequency
- 5 times a day
- Estimated price
- €30–50
- Website
- Italo Treno
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 47m
- Frequency
- 5 times a day
- Estimated price
- €30–50
- Website
- Italo Treno
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- Trenitalia Eurocity
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- Trenitalia Eurocity
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- €10–18
- Website
- Trenitalia Intercity
Train from Pisa Centrale to Ventimiglia
- Ave. Duration
- 4h 36m
- Frequency
- Once daily
- Estimated price
- €30–60
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- 6 times a week
- Estimated price
- €28–55
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- 6 times a week
- Estimated price
- €28–55
- Website
- Trenitalia Intercity
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Lyon Part Dieu to Avignon Tgv
- Ave. Duration
- 1h 1m
- Frequency
- Every 3 hours
- Estimated price
- €45–70
- Website
- TGV inOui
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €14–22
- Website
- TGV inOui
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €14–22
- Website
- TGV inOui
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €14–22
- Website
- TGV inOui
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €14–22
- Website
- TGV inOui
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Avignon Tgv
- Ave. Duration
- 1h 2m
- Frequency
- 3 times a day
- Estimated price
- €40–70
- Website
- Oui.SNCF
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 21 min
- Frequency
- Every 4 hours
- Estimated price
- €13–22
- Website
- Oui.SNCF
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 21 min
- Frequency
- Every 4 hours
- Estimated price
- €13–22
- Website
- Oui.SNCF
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 21 min
- Frequency
- Every 4 hours
- Estimated price
- €13–22
- Website
- Oui.SNCF
Train from Lyon-Saint Exupery Tgv to Avignon Tgv
- Ave. Duration
- 51 min
- Frequency
- Twice daily
- Estimated price
- €35–65
- Website
- Oui.SNCF
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 21 min
- Frequency
- Every 4 hours
- Estimated price
- €13–22
- Website
- Oui.SNCF
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Lyon Part Dieu to Avignon Tgv
- Ave. Duration
- 1h 3m
- Frequency
- Once daily
- Estimated price
- €40–65
- Website
- Belgian Railways
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Toulon to Marseille Saint-Charles
- Ave. Duration
- 58 min
- Frequency
- Every 30 minutes
- Estimated price
- €17–24
- Website
- Zou! Lignes Express Régionales
Train from Marseille Saint-Charles to Avignon Centre
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- €30–45
- Website
- Zou! Lignes Express Régionales
Train from Nice-Ville to Marseille-Saint-Charles
- Ave. Duration
- 2h 38m
- Frequency
- Hourly
- Estimated price
- €55–80
- Website
- Zou! Lignes Express Régionales
Train from Marseille Saint-Charles to Avignon Centre
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- €30–45
- Website
- Zou! Lignes Express Régionales
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 20 min
- Frequency
- Twice daily
- Estimated price
- €9–14
- Website
- Renfe Viajeros
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 20 min
- Frequency
- Twice daily
- Estimated price
- €9–14
- Website
- Renfe Viajeros
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 20 min
- Frequency
- Twice daily
- Estimated price
- €9–14
- Website
- Renfe Viajeros
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 20 min
- Frequency
- Twice daily
- Estimated price
- €9–14
- Website
- Renfe Viajeros
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Siena to Florence Villa Constanza Bus Station
- Ave. Duration
- 50 min
- Frequency
- Every 3 hours
- Estimated price
- €5–9
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Marseille, Gare de Marseille-Saint-Charles
- Ave. Duration
- 8h 55m
- Frequency
- Once daily
- Estimated price
- €55–85
- Website
- Flixbus
Bus from Marseille - Saint-Charles Bus Station to Avignon - Le Pontet - Le Lac Stop
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- €8–13
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Marseille - Saint-Charles Bus Station to Avignon - Le Pontet - Le Lac Stop
- Ave. Duration
- 1h 20m
- Frequency
- Every 2 hours
- Estimated price
- €7–13
- Website
- BlaBlaCar Bus
- Phone
- +39 199 168 182
- info@tiemmespa.it
- Website
- tiemmespa.it
Bus from Siena-Via Tozzi to Port of Piombino
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- €18–22
- Schedules at
- tiemmespa.it
Bus from Colonna San Marco to Port of Piombino
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- €9–12
- Schedules at
- tiemmespa.it
- Phone
- +33(0)495329595
- Website
- corsica-ferries.it
Ferry from Port of Piombino to Port of Bastia
- Ave. Duration
- 3h 30m
- Frequency
- Twice a week
- Estimated price
- €15–26
- Schedules at
- corsica-ferries.it
- Book at
- corsica-ferries.it
Ferry from Port of Bastia to Port of Toulon
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- €45–80
- Schedules at
- corsica-ferries.it
- Book at
- corsica-ferries.it
Ferry from Port of Piombino to Port of Bastia
- Ave. Duration
- 3h 30m
- Frequency
- Twice a week
- Estimated price
- €15–26
- Schedules at
- corsica-ferries.it
- Book at
- corsica-ferries.it
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Booking & Getting There
Siena to Avignon bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Siena to Avignon train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Siena to Avignon is 711 km. It takes approximately 7h 54m to drive from Siena to Avignon.
Book your Siena to Avignon train tickets online with Omio.
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