There are 10 ways to get from Siena to Avignon by train (Trenitalia, TGV), bus, car, train, plane, train (Trenitalia), or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Siena to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Bologna Centraletrain Fr
- Take the train from Bologna centrale to Milano Centraletrain
- Take the train from Milano Centrale to Lyon Part Dieutrain Fr
- Take the train from Lyon Part Dieu to Avignon Tgvtrain Tgv
11h 12m€138–314Bus via Genoa
cheapest- Take the bus from Siena to Genoabus 516 / ...
- Take the bus from Genoa to Avignonbus 1922
14h 15m€58–101Bus
- Take the bus from Siena to Aix-en-Provence - Krypton Park & Ridebus BlaBlaCar Bus
- Take the bus from La Beauvalle to Limbert/Voie d'Insertionbus 63
13h 25mDrive 711.6 km
- Drive from Siena to Avignoncar 711.6 km
7h 55m€111–160Train to Florence Peretola Airport, fly to Marseille Provence Airport, train
- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Marseille Provence Airport (MRS)plane FLR - MRS
- Take the train from Aix En Provence Tgv to Avignon Tgvtrain
10h 3m€106–250Train via Ventimiglia
- Take the train from Siena to Empolitrain Re
- Take the train from Empoli to Pisa Centraletrain Re
- Take the train from Pisa Centrale to Ventimigliatrain Ic
- Take the train from Ventimiglia to Nice Saint-Augustintrain C3
- Take the train from Nice-Saint-Augustin to Marseille-Saint-Charlestrain
- Take the train from Marseille St Charles to Avignon Centretrain Ter
14h 11m€128–284Train, train to Bologna Guglielmo Marconi Airport, fly to Marseille Provence Airport
- Take the train from Siena to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Marseille Provence Airport (MRS)plane BLQ - MRS
- Take the train from Aix En Provence Tgv to Avignon Tgvtrain
7h 13m€78–298Bus, ferry to Bastia - Poretta Airport, fly to Marseille Provence Airport, train
- Take the bus from Colonna San Marco to Port of Piombinobus
- Take the ferry from Port of Piombino to Port of Bastiaferry
- Fly from Bastia - Poretta Airport (BIA) to Marseille Provence Airport (MRS)plane BIA - MRS
- Take the train from Aix En Provence Tgv to Avignon Tgvtrain
10h 47m€133–338Train to Florence Peretola Airport, fly to Nice Côte D'Azur International Airport, train
- Take the train from Siena to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Nice Côte D'Azur International Airport (NCE)plane FLR - NCE
- Take the train from Nice-Saint-Augustin to Marseille-Saint-Charlestrain
- Take the train from Marseille St Charles to Avignon Tgvtrain
9h 50m€172–378Train, train to Fiumicino International Airport, fly to Marseille Provence Airport
- Take the train from Siena to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Marseille Provence Airport (MRS)plane FCO - MRS
- Take the train from Aix En Provence Tgv to Avignon Tgvtrain
8h 59m€95–310
Siena to Avignon by train
Comparing Your Travel Options
The cheapest way to get from Siena to Avignon is to bus via Genoa which costs €55 - €110 and takes 14h 15m.
The fastest way to get from Siena to Avignon is to train and fly which takes 7h 13m and costs €75 - €300.
No, there is no direct bus from Siena to Avignon. However, there are services departing from Siena and arriving at Limbert/Voie d'Insertion via La Beauvalle. The journey, including transfers, takes approximately 13h 25m.
No, there is no direct train from Siena to Avignon. However, there are services departing from Siena and arriving at Avignon Tgv via Firenze S.M.N., Bologna centrale, Milano Centrale and Lyon Part Dieu. The journey, including transfers, takes approximately 11h 12m.
The distance between Siena and Avignon is 1068 km. The road distance is 711.6 km.
The best way to get from Siena to Avignon without a car is to train which takes 11h 12m and costs €130 - €320.
It takes approximately 11h 12m to get from Siena to Avignon, including transfers.
Siena to Avignon bus services, operated by FlixBus, depart from Siena station.
Siena to Avignon train services, operated by Trenitalia, depart from Siena station.
The best way to get from Siena to Avignon is to train which takes 11h 12m and costs €130 - €320. Alternatively, you can bus, which costs and takes 13h 25m.
What companies run services between Siena, Italy and Avignon, France?
You can take a train from Siena to Avignon Tgv via Firenze S.M.N., Bologna centrale, Milano Centrale, and Lyon Part Dieu in around 11h 12m. Alternatively, you can take a bus from Siena to Limbert/Voie d'Insertion via Aix-en-Provence - Krypton Park & Ride and La Beauvalle in around 13h 25m.
- Website
- ryanair.com
Flights from Florence Peretola Airport to Marseille Provence Airport via Fiumicino International Airport
- Ave. Duration
- 5h 42m
- When
- Friday, Tuesday, and Thursday
- Estimated price
- €70–200
Flights from Bologna Guglielmo Marconi Airport to Marseille Provence Airport
- Ave. Duration
- 1h 25m
- When
- Wednesday, Thursday, and Sunday
- Estimated price
- €35–160
Flights from Fiumicino International Airport to Marseille Provence Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €35–160
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Marseille Provence Airport via Fiumicino International Airport
- Ave. Duration
- 7h
- When
- Every day
- Estimated price
- €95–160
Flights from Florence Peretola Airport to Nice Côte D'Azur International Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €170–310
Flights from Florence Peretola Airport to Nice Côte D'Azur International Airport via Fiumicino International Airport
- Ave. Duration
- 3h 2m
- When
- Every day
- Estimated price
- €100–190
Flights from Fiumicino International Airport to Marseille Provence Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €70–150
- Website
- aircorsica.com
Flights from Bastia - Poretta Airport to Marseille Provence Airport
- Ave. Duration
- 58 min
- When
- Every day
- Estimated price
- €75–310
Flights from Florence Peretola Airport to Nice Côte D'Azur International Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €170–310
- Website
- swiss.com
Flights from Florence Peretola Airport to Marseille Provence Airport via Zurich
- Ave. Duration
- 7h 25m
- When
- Wednesday
- Estimated price
- €100–370
Flights from Bologna Guglielmo Marconi Airport to Marseille Provence Airport via Zurich
- Ave. Duration
- 3h 45m
- When
- Wednesday
- Estimated price
- €95–320
- Website
- volotea.com
Flights from Florence Peretola Airport to Marseille Provence Airport via Cagliari
- Ave. Duration
- 7h 15m
- When
- Saturday
- Estimated price
- €75–220
- Website
- twinjet.fr
Flights from Florence Peretola Airport to Marseille Provence Airport via Toulouse
- Ave. Duration
- 8h 25m
- When
- Thursday
- Estimated price
- €75–220
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- Twice daily
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Milano Centrale to Lyon Part Dieu
- Ave. Duration
- 4h 39m
- Frequency
- Twice daily
- Estimated price
- €55–90
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 20 min
- Frequency
- 4 times a day
- Estimated price
- €9–15
- Website
- Trenitalia
Train from Siena to Empoli
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- €7–13
- Website
- Trenitalia
Train from Empoli to Pisa Centrale
- Ave. Duration
- 46 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–10
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- Twice daily
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 20 min
- Frequency
- 4 times a day
- Estimated price
- €9–15
- Website
- Trenitalia
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 20 min
- Frequency
- 4 times a day
- Estimated price
- €9–15
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Marseille St Charles to Avignon Tgv
- Ave. Duration
- 34 min
- Frequency
- 4 times a day
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- 4 times a day
- Estimated price
- €30–55
- Website
- Trenitalia
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 20 min
- Frequency
- 4 times a day
- Estimated price
- €9–15
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €13–27
- Schedules at
- Trenitalia Frecce
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €13–27
- Schedules at
- Trenitalia Frecce
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 52m
- Frequency
- Every 30 minutes
- Estimated price
- €35–75
- Schedules at
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 45 min
- Frequency
- 4 times a day
- Estimated price
- €11–23
- Website
- Italo Treno
Train from Bologna centrale to Milano Centrale
- Ave. Duration
- 1h 4m
- Frequency
- Every 30 minutes
- Estimated price
- €27–55
- Website
- Italo Treno
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 45 min
- Frequency
- 4 times a day
- Estimated price
- €11–23
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- €9–21
- Website
- Trenitalia Intercity
Train from Pisa Centrale to Ventimiglia
- Ave. Duration
- 4h 33m
- Frequency
- Once daily
- Estimated price
- €30–70
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- €9–21
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- 6 times a week
- Estimated price
- €27–60
- Website
- Trenitalia Intercity
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- Trenitalia Eurocity
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- Trenitalia Eurocity
- 1st Class
- €45–70
- 2nd Class
- €27–40
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- Trenitalia Eurocity
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Lyon Part Dieu to Avignon Tgv
- Ave. Duration
- 1h 1m
- Frequency
- Every 2 hours
- Estimated price
- €45–75
- Website
- TGV inOui
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 21 min
- Frequency
- Hourly
- Estimated price
- €14–24
- Website
- TGV inOui
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 21 min
- Frequency
- Hourly
- Estimated price
- €14–24
- Website
- TGV inOui
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 21 min
- Frequency
- Hourly
- Estimated price
- €14–24
- Website
- TGV inOui
Train from Marseille St Charles to Avignon Tgv
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- €18–30
- Website
- TGV inOui
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 21 min
- Frequency
- Hourly
- Estimated price
- €14–24
- Website
- TGV inOui
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Avignon Tgv
- Ave. Duration
- 1h 2m
- Frequency
- Twice daily
- Estimated price
- €35–75
- Website
- Oui.SNCF
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 22 min
- Frequency
- 5 times a day
- Estimated price
- €12–25
- Website
- Oui.SNCF
Train from Marseille St Charles to Avignon Centre
- Ave. Duration
- 1h 52m
- Frequency
- Hourly
- Estimated price
- €20–40
- Website
- Oui.SNCF
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 22 min
- Frequency
- 5 times a day
- Estimated price
- €12–25
- Website
- Oui.SNCF
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 22 min
- Frequency
- 5 times a day
- Estimated price
- €12–25
- Website
- Oui.SNCF
Train from Marseille St Charles to Avignon Tgv
- Ave. Duration
- 36 min
- Frequency
- Every 4 hours
- Estimated price
- €15–35
- Website
- Oui.SNCF
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 22 min
- Frequency
- 5 times a day
- Estimated price
- €12–25
- Website
- Oui.SNCF
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Lyon Part Dieu to Avignon Tgv
- Ave. Duration
- 1h 3m
- Frequency
- Once daily
- Estimated price
- €40–80
- Website
- Belgian Railways
- Phone
- +34 91 232 03 20
- Website
- Renfe Viajeros
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 19 min
- Frequency
- Twice daily
- Estimated price
- €9–15
- Website
- Renfe Viajeros
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 19 min
- Frequency
- Twice daily
- Estimated price
- €9–15
- Website
- Renfe Viajeros
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 19 min
- Frequency
- Twice daily
- Estimated price
- €9–15
- Website
- Renfe Viajeros
Train from Marseille St Charles to Avignon Tgv
- Ave. Duration
- 33 min
- Frequency
- Twice daily
- Estimated price
- €11–18
- Website
- Renfe Viajeros
Train from Aix En Provence Tgv to Avignon Tgv
- Ave. Duration
- 19 min
- Frequency
- Twice daily
- Estimated price
- €9–15
- Website
- Renfe Viajeros
- Phone
- +33 4 13 94 30 50
- Website
- ZOU!
Train from Ventimiglia to Nice Saint-Augustin
- Ave. Duration
- 1h 5m
- Frequency
- Every 15 minutes
- Schedules at
- ZOU!
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Ventimiglia to Nice Saint-Augustin
- Ave. Duration
- 1h 7m
- Frequency
- Hourly
- Estimated price
- €10–21
- Website
- Zou! Lignes Express Régionales
Train from Nice-Saint-Augustin to Marseille-Saint-Charles
- Ave. Duration
- 2h 32m
- Frequency
- Hourly
- Estimated price
- €55–110
- Website
- Zou! Lignes Express Régionales
Train from Marseille St Charles to Avignon Centre
- Ave. Duration
- 1h 52m
- Frequency
- Hourly
- Estimated price
- €30–60
- Website
- Zou! Lignes Express Régionales
Train from Nice-Saint-Augustin to Marseille-Saint-Charles
- Ave. Duration
- 2h 32m
- Frequency
- Hourly
- Estimated price
- €55–110
- Website
- Zou! Lignes Express Régionales
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Siena to Aix-en-Provence - Krypton Park & Ride
- Ave. Duration
- 11h 10m
- Frequency
- Twice a week
- Estimated price
- €60–110
- Website
- BlaBlaCar Bus
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Bus from La Beauvalle to Limbert/Voie d'Insertion
- Ave. Duration
- 1h 4m
- Frequency
- Every 4 hours
- Website
- Zou! Lignes Express Régionales
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Siena to Genoa
- Ave. Duration
- 4h 25m
- Frequency
- Twice daily
- Estimated price
- €22–40
- Website
- Flixbus
Bus from Genoa to Avignon
- Ave. Duration
- 8h 50m
- Frequency
- Twice a week
- Estimated price
- €35–65
- Website
- Flixbus
- Phone
- +39 199 168 182
- info@tiemmespa.it
- Website
- tiemmespa.it
Bus from Colonna San Marco to Port of Piombino
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- €9–12
- Schedules at
- tiemmespa.it
- Phone
- +33(0)495329595
- Website
- Corsica Ferries/Sardinia Ferries
Ferry from Port of Piombino to Port of Bastia
- Ave. Duration
- 3h 30m
- Frequency
- Twice a week
- Estimated price
- €11–20
- Website
- Corsica Ferries/Sardinia Ferries
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Booking & Getting There
Siena to Avignon bus services, operated by FlixBus, arrive at Genoa station.
Siena to Avignon train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Siena to Avignon is 712 km. It takes approximately 7h 55m to drive from Siena to Avignon.
Book your Siena to Avignon train tickets online with Omio.
Book your Siena to Avignon bus tickets online with Omio and FlixBus.
There are 4757+ hotels available in Avignon.
























































