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How to get fromSiena to Avignonby train (Trenitalia, TGV), bus, car, train, plane, or ferry

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There are 10 ways to get from Siena to Avignon by train (Trenitalia, TGV), bus, car, train, plane, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Lyon Part Dieutrain train Fr
    4. Take the train from Lyon Part Dieu to Avignon Tgvtrain train Tgv
    10h 55m
    €118–235

  2. Bus via Genoa

    cheapest
    1. Take the bus from Siena to Genoabus bus 516 / ...
    2. Take the bus from Genoa - Via Fanti d'Italia Bus Stop to Marseille - Saint-Charles Bus Stationbus bus
    3. Take the bus from Marseille - Saint-Charles Bus Station to Avignon - Le Pontet - Le Lac Stopbus bus
    13h 51m
    €55–93

  3. Bus

    1. Take the bus from Siena to Florence Villa Constanza Bus Stationbus bus 443 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Marseille, Gare de Marseille-Saint-Charlesbus bus
    3. Take the bus from Marseille - Saint-Charles Bus Station to Avignon - Le Pontet - Le Lac Stopbus bus
    13h 2m
    €63–101

  4. Drive  711.4 km

    1. Drive from Siena to Avignoncar car 711.4 km
    7h 55m
    €116–167

  5. Train to Florence Peretola Airport, fly to Marseille Provence Airport, train

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Marseille Provence Airport (MRS)plane plane FLR - MRS
    3. Take the train from Aix En Provence Tgv to Avignon Tgvtrain train
    9h 21m
    €104–263

  6. Train via Ventimiglia

    1. Take the train from Siena to Empolitrain train Re
    2. Take the train from Empoli to Pisa Centraletrain train Re
    3. Take the train from Pisa Centrale to Ventimigliatrain train Ic
    4. Take the train from Nice Ville to Avignon Tgvtrain train Tgv
    12h 55m
    €112–186

  7. Train, train to Bologna Guglielmo Marconi Airport, fly to Marseille Provence Airport

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Marseille Provence Airport (MRS)plane plane BLQ - MRS
    4. Take the train from Aix En Provence Tgv to Avignon Tgvtrain train
    6h 58m
    €76–301

  8. Bus, ferry to Bastia - Poretta Airport, fly to Marseille Provence Airport, train

    1. Take the bus from Colonna San Marco to Port of Piombinobus bus
    2. Take the ferry from Port of Piombino to Port of Bastiaferry ferry
    3. Fly from Bastia - Poretta Airport (BIA) to Marseille Provence Airport (MRS)plane plane BIA - MRS
    4. Take the train from Aix En Provence Tgv to Avignon Tgvtrain train
    10h 36m
    €161–361

  9. Train to Florence Peretola Airport, fly to Nice Côte D'Azur International Airport, train

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Nice Côte D'Azur International Airport (NCE)plane plane FLR - NCE
    3. Take the train from Nice-Saint-Augustin to Marseille-Saint-Charlestrain train
    4. Take the train from Marseille St Charles to Avignon Tgvtrain train
    9h 37m
    €171–347

  10. Train, train to Fiumicino International Airport, fly to Marseille Provence Airport

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Roma Terminitrain train
    3. Fly from Fiumicino International Airport (FCO) to Marseille Provence Airport (MRS)plane plane FCO - MRS
    4. Take the train from Aix En Provence Tgv to Avignon Tgvtrain train
    8h 27m
    €97–302

Siena to Avignon by train

Calendar28Weekly Trains
Duration10h 55mAverage Duration
Ticket€118Cheapest Price
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Comparing Your Travel Options

Map of how to get from Siena to Avignon.ExpandLaunch map view
  • Distance: 1,068.6 km
  • Duration: 10h 55m

What companies run services between Siena, Italy and Avignon, France?

You can take a train from Siena to Avignon Tgv via Firenze S.M.N., Milano Centrale, and Lyon Part Dieu in around 10h 55m. Alternatively, you can take a bus from Siena to Thiers via Florence Villa Constanza Bus Station, Marseille - Saint-Charles Bus Station, and Le Lac in around 13h 2m.

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