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How to get fromSiena to Avignonby train (TGV), bus, car, train, plane or train (Trenitalia, TGV)

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There are 9 ways to get from Siena to Avignon by train (TGV), bus, car, train, plane, or train (Trenitalia, TGV)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Siena to Firenze S.M.N.trainRe
    2. Take the train from Florence Santa Maria Novella to Milano Centraletrain
    3. Take the train from Milano Centrale to Lyon Part DieutrainFr
    4. Take the train from Lyon Part Dieu to Avignon TgvtrainTgv
    11h 56m
    €113–300
  2. Bus via Genoa

    cheapest
    1. Take the bus from Siena Central Train Station to Genoa Piazza della VittoriabusItabus
    2. Take the bus from Genoa Piazza Acquaverde to Avignon Le Pontet Bus StationbusUnion Ivkoni - Unibus 3577 / ...
    13h 15m
    €31–58
  3. Bus

    1. Take the bus from Siena to Florence Villa Constanza Bus Stationbus443 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Marseille, Gare de Marseille-Saint-Charlesbus
    3. Take the bus from Marseille, Gare de Marseille-Saint-Charles to Avignonbus
    12h 45m
    €46–127
  4. Drive 711.1 km

    1. Drive from Siena to Avignoncar711.1 km
    7h 47m
    €110–159
  5. Train to Florence Peretola Airport, fly to Marseille Provence Airport, train

    1. Take the train from Siena to Firenze S.M.N.train
    2. Fly from Florence Peretola Airport (FLR) to Marseille Provence Airport (MRS)planeFLR - MRS
    3. Take the train from Aix En Provence Tgv to Avignon Tgvtrain
    9h 30m
    €101–297
  6. Train via Ventimiglia

    1. Take the train from Siena to EmpolitrainRe
    2. Take the train from Empoli to Pisa CentraletrainRe
    3. Take the train from Pisa Centrale to VentimigliatrainIc
    4. Take the train from Nice Ville to Avignon TgvtrainTgv
    12h 53m
    €93–151
  7. Train to Florence Peretola Airport, fly to Nice Côte D'Azur International Airport, train

    1. Take the train from Siena to Firenze S.M.N.train
    2. Fly from Florence Peretola Airport (FLR) to Nice Côte D'Azur International Airport (NCE)planeFLR - NCE
    3. Take the train from Antibes to Avignon Tgvtrain
    9h 42m
    €130–263
  8. Train, train to Venice Marco Polo Airport, fly to Marseille Provence Airport

    1. Take the train from Siena to Firenze S.M.N.train
    2. Take the train from Firenze S.M.N. to Venezia Mestretrain
    3. Fly from Venice Marco Polo Airport (VCE) to Marseille Provence Airport (MRS)planeVCE - MRS
    4. Take the train from Aix En Provence Tgv to Avignon Tgvtrain
    9h 39m
    €96–285
  9. Train, train to Roma Ciampino Airport, fly to Marseille Provence Airport

    1. Take the train from Siena to Firenze S.M.N.train
    2. Take the train from Florence Santa Maria Novella to Roma Terminitrain
    3. Fly from Roma Ciampino Airport (CIA) to Marseille Provence Airport (MRS)planeCIA - MRS
    4. Take the train from Aix En Provence Tgv to Avignon Tgvtrain
    9h 6m
    €85–311

Siena to Avignon by train

Calendar14Weekly Trains
Duration11h 56mAverage Duration
Ticket€113Cheapest Price
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Questions & Answers

What companies run services between Siena, Italy and Avignon, France?

You can take a train from Siena to Avignon Tgv via Florence Santa Maria Novella, Milano Centrale, and Lyon Part Dieu in around 11h 56m. Alternatively, you can take a bus from Siena to Avignon via Florence Villa Constanza Bus Station and Marseille, Gare de Marseille-Saint-Charles in around 12h 45m.

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