There are 9 ways to get from Siena to Lyon by bus, train, car, plane, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131
- Take the train from Florence Santa Maria Novella to Milano Centraletrain
- Take the train from Milano Centrale to Lyon Part Dieutrain Fr
9h 37mBus
cheapest- Take the bus from Siena to Lyonbus 516 / ...
12h€45–95Drive 727.5 km
- Drive from Siena to Lyoncar 727.5 km
8h 5m€112–161Bus, train to Bologna Guglielmo Marconi Airport, fly to Lyon–Saint Exupéry Airport
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Lyon–Saint Exupéry Airport (LYS)plane BLQ - LYS
6h 34mTrain (Trenitalia)
- Take the train from Siena to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Torino Porta Susatrain Fr
- Take the train from Torino Porta Susa to Lyon Part Dieutrain Fr
10h 16m€100–250Bus via Florence
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131R / ...
- Take the bus from Florence Villa Constanza Bus Station to Lyon Lyon Perrache Bus Stationbus Itabus
14h 29mBus to Florence Peretola Airport, fly to Geneva International Airport, train
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Fly from Florence Peretola Airport (FLR) to Geneva International Airport (GVA)plane FLR - GVA
- Take the train from Bellegarde to Lyon Part Dieutrain
10h 36mBus, train to Fiumicino International Airport, fly to Lyon–Saint Exupéry Airport
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Take the train from Florence Santa Maria Novella to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Lyon–Saint Exupéry Airport (LYS)plane FCO - LYS
8h 17mBus, train to Venice Marco Polo Airport, fly to Lyon–Saint Exupéry Airport
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Take the train from Firenze S.M.N. to Venezia Mestretrain
- Fly from Venice Marco Polo Airport (VCE) to Lyon–Saint Exupéry Airport (LYS)plane VCE - LYS
8h 42m
Bologna Guglielmo Marconi Airport (BLQ) to Lyon–Saint Exupéry Airport (LYS) flights
Questions & Answers
The cheapest way to get from Siena to Lyon is to bus which costs €45 - €95 and takes 12h.
The fastest way to get from Siena to Lyon is to drive which takes 8h 5m and costs €110 - €170.
Yes, there is a direct bus departing from Siena and arriving at Lyon. Services depart once daily, and operate Monday, Thursday, Friday, Saturday and Sunday. The journey takes approximately 12h.
No, there is no direct train from Siena to Lyon. However, there are services departing from Siena and arriving at Lyon Part Dieu via Firenze S.M.N. and Torino Porta Susa. The journey, including transfers, takes approximately 10h 16m.
The distance between Siena and Lyon is 818 km. The road distance is 727.5 km.
The best way to get from Siena to Lyon without a car is to bus and train which takes 9h 37m and costs .
It takes approximately 9h 37m to get from Siena to Lyon, including transfers.
Siena to Lyon bus services, operated by FlixBus, depart from Siena station.
Siena to Lyon train services, operated by Trenitalia, depart from Siena station.
The best way to get from Siena to Lyon is to bus which takes 12h and costs €45 - €95. Alternatively, you can train, which costs €100 - €250 and takes 10h 16m.
What companies run services between Siena, Italy and Lyon, France?
FlixBus operates a bus from Siena to Lyon once daily. Tickets cost €45–95 and the journey takes 12h. Alternatively, you can take a train from Siena to Lyon Part Dieu via Firenze S.M.N. and Torino Porta Susa in around 10h 16m.
- Website
- lufthansa.com
Flights from Bologna Guglielmo Marconi Airport to Lyon–Saint Exupéry Airport via Frankfurt
- Ave. Duration
- 3h 45m
- When
- Monday, Wednesday, and Saturday
- Estimated price
- €85–340
Flights from Florence Peretola Airport to Geneva International Airport via Frankfurt
- Ave. Duration
- 4h 23m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €95–400
Flights from Florence Peretola Airport to Geneva International Airport via Munich
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- €130–380
- Website
- easyjet.com
Flights from Fiumicino International Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- €30–130
Flights from Venice Marco Polo Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €28–140
- Website
- swiss.com
Flights from Florence Peretola Airport to Geneva International Airport via Zurich
- Ave. Duration
- 3h 3m
- When
- Every day
- Estimated price
- €75–350
Flights from Florence Peretola Airport to Geneva International Airport via Fiumicino International Airport
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- €70–200
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Geneva International Airport via Zurich
- Ave. Duration
- 3h
- When
- Wednesday, Friday, and Sunday
- Estimated price
- €75–350
Flights from Florence Peretola Airport to Geneva International Airport via Fiumicino International Airport
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- €70–200
- Website
- airdolomiti.it
Flights from Florence Peretola Airport to Geneva International Airport via Frankfurt
- Ave. Duration
- 3h 40m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €140–400
Flights from Florence Peretola Airport to Geneva International Airport via Munich
- Ave. Duration
- 6h
- When
- Sunday
- Estimated price
- €130–380
- Website
- twinjet.fr
Flights from Bologna Guglielmo Marconi Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 30m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- €420–950
- Website
- volotea.com
Flights from Venice Marco Polo Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 25m
- When
- Thursday and Sunday
- Estimated price
- €24–160
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €26–70
- Website
- https://www.italotreno.it/en
Train from Florence Santa Maria Novella to Roma Termini
- Ave. Duration
- 1h 32m
- Frequency
- Hourly
- Estimated price
- €22–50
- Website
- https://www.italotreno.it/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Milano Centrale to Lyon Part Dieu
- Ave. Duration
- 4h 39m
- Frequency
- Twice daily
- Estimated price
- €50–110
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 44m
- Frequency
- Twice daily
- Estimated price
- €9–10
- Website
- https://www.trenitalia.com/en.html
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €11
- Website
- https://www.trenitalia.com/en.html
Train from Torino Porta Susa to Lyon Part Dieu
- Ave. Duration
- 3h 52m
- Frequency
- Twice daily
- Estimated price
- €50–110
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €15–35
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Torino Porta Susa
- Ave. Duration
- 2h 54m
- Frequency
- Hourly
- Estimated price
- €40–130
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Venezia Mestre
- Ave. Duration
- 2h 3m
- Frequency
- Hourly
- Estimated price
- €25–60
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- €9–15
- Website
- https://www.trenitalia.com/en.html
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Bellegarde to Lyon Part Dieu
- Ave. Duration
- 1h 32m
- Frequency
- Once daily
- Estimated price
- €28–35
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Bellegarde to Lyon Part Dieu
- Ave. Duration
- 1h 11m
- Frequency
- Once daily
- Estimated price
- €28–65
- Website
- https://www.sncf-connect.com/en-en
- 2nd Class
- €28–40
- 1st Class
- €45–65
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Siena-Via Tozzi to Firenze Autostazione
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.at-bus.it/en
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Siena to Lyon
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- €45–95
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Florence Villa Constanza Bus Station to Lyon Lyon Perrache Bus Station
- Ave. Duration
- 11h 50m
- Frequency
- Twice daily
- Estimated price
- €25–70
- Website
- https://www.itabus.it/en/home
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Florence Villa Constanza Bus Station to Lyon Lyon Perrache Bus Station
- Ave. Duration
- 11h
- Frequency
- 6 times a week
- Estimated price
- €30–55
- Website
- https://www.blablacar.co.uk/bus
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More Questions & Answers
Siena to Lyon bus services, operated by FlixBus, arrive at Lyon station.
Siena to Lyon train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Siena to Lyon is 728 km. It takes approximately 8h 5m to drive from Siena to Lyon.
Book your Siena to Lyon train tickets online with Omio.
Book your Siena to Lyon bus tickets online with Omio and FlixBus.
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