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How to get fromSiena to Lyonby train (Trenitalia), bus, car, train, plane, or train (Trenitalia, TGV)

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There are 9 ways to get from Siena to Lyon by train (Trenitalia), bus, car, train, plane, or train (Trenitalia, TGV)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train Fr
    3. Take the train from Bologna centrale to Milano Centraletrain train
    4. Take the train from Milano Centrale to Lyon Part Dieutrain train Fr
    9h 24m
    €102–234

  2. Bus via Florence

    cheapest
    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus bus 131R / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Lyon Lyon Perrache Bus Stationbus bus Itabus
    14h 36m
    €52–98

  3. Bus

    1. Take the bus from Siena to Lyonbus bus 516 / ...
    12h
    €60–120

  4. Drive 727.3 km

    1. Drive from Siena to Lyoncar car 727.3 km
    8h 6m
    €116–167

  5. Train, train to Bologna Guglielmo Marconi Airport, fly to Lyon–Saint Exupéry Airport

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Lyon–Saint Exupéry Airport (LYS)plane plane BLQ - LYS
    6h 47m
    €107–275

  6. Train via Turin

    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Torino Porta Susatrain train Fr
    3. Take the train from Torino Porta Susa to Chambery Challes Les Eauxtrain train Tgv
    4. Take the train from Chambery Challes Les Eaux to Lyon Part Dieutrain train Ter
    10h 21m
    €114–259

  7. Train, train to Venice Marco Polo Airport, fly to Lyon–Saint Exupéry Airport

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Venezia Mestretrain train
    3. Fly from Venice Marco Polo Airport (VCE) to Lyon–Saint Exupéry Airport (LYS)plane plane VCE - LYS
    8h 41m
    €99–277

  8. Train to Florence Peretola Airport, fly to Geneva International Airport, train

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Geneva International Airport (GVA)plane plane FLR - GVA
    3. Take the train from Bellegarde to Lyon Part Dieutrain train
    10h 49m
    €145–373

  9. Train, train to Fiumicino International Airport, fly to Lyon–Saint Exupéry Airport

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Roma Terminitrain train
    3. Fly from Fiumicino International Airport (FCO) to Lyon–Saint Exupéry Airport (LYS)plane plane FCO - LYS
    8h 41m
    €118–287

Siena to Lyon by bus

Calendar16Weekly Buses
Duration12hAverage Duration
Ticket€60Cheapest Price
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Questions & Answers

Map of how to get from Siena to Lyon.ExpandLaunch map view
  • Distance: 841.5 km
  • Duration: 9h 24m

What companies run services between Siena, Italy and Lyon, France?

You can take a train from Siena to Lyon Part Dieu via Firenze S.M.N., Bologna centrale, and Milano Centrale in around 9h 24m. Alternatively, FlixBus operates a bus from Siena to Lyon once daily. Tickets cost €60–100 and the journey takes 12h. BlaBlaCar Bus also services this route once daily.

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