There are 9 ways to get from Siena to Lyon by bus, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131
- Take the train from Firenze S.M.N. to Milano Centraletrain Fr
- Take the train from Milano Centrale to Lyon Part Dieutrain Fr
9h 42m€90–186Bus
cheapest- Take the bus from Siena to Lyonbus 516 / ...
12h€45–85Drive 727.5 km
- Drive from Siena to Lyoncar 727.5 km
8h 5m€114–164Bus, train to Bologna Guglielmo Marconi Airport, fly to Lyon–Saint Exupéry Airport
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Take the train from Firenze S.M.N. to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Lyon–Saint Exupéry Airport (LYS)plane BLQ - LYS
6h 38m€84–291Bus via Florence
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus 131R / ...
- Take the bus from Florence Villa Constanza Bus Station to Lyon - Perrache Bus Stationbus BlaBlaCar Bus
13h 39m€52–93Bus to Florence Peretola Airport, fly to Lyon–Saint Exupéry Airport
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Fly from Florence Peretola Airport (FLR) to Lyon–Saint Exupéry Airport (LYS)plane FLR - LYS
5h 45m€92–233Bus to Florence Peretola Airport, fly to Geneva International Airport, train
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Fly from Florence Peretola Airport (FLR) to Geneva International Airport (GVA)plane FLR - GVA
- Take the train from Bellegarde to Lyon Part Dieutrain
10h 15m€105–314Bus, train to Fiumicino International Airport, fly to Lyon–Saint Exupéry Airport
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Take the train from Firenze S.M.N. to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Lyon–Saint Exupéry Airport (LYS)plane FCO - LYS
8h 17m€94–283Bus, train to Venice Marco Polo Airport, fly to Lyon–Saint Exupéry Airport
- Take the bus from Siena-Via Tozzi to Firenze Autostazionebus
- Take the train from Firenze S.M.N. to Venezia Mestretrain
- Fly from Venice Marco Polo Airport (VCE) to Lyon–Saint Exupéry Airport (LYS)plane VCE - LYS
8h 45m€79–286
Siena to Lyon by bus and train
Questions & Answers
The cheapest way to get from Siena to Lyon is to bus which costs €45 - €85 and takes 12h.
The fastest way to get from Siena to Lyon is to bus and fly which takes 5h 45m and costs €90 - €240.
Yes, there is a direct bus departing from Siena and arriving at Lyon. Services depart once daily, and operate Monday, Thursday, Friday, Saturday and Sunday. The journey takes approximately 12h.
The distance between Siena and Lyon is 818 km. The road distance is 727.5 km.
The best way to get from Siena to Lyon without a car is to bus and train which takes 9h 42m and costs €90 - €190.
It takes approximately 9h 42m to get from Siena to Lyon, including transfers.
Siena to Lyon bus services, operated by FlixBus, depart from Siena station.
Siena to Lyon bus services, operated by FlixBus, arrive at Lyon station.
Yes, the driving distance between Siena to Lyon is 728 km. It takes approximately 8h 5m to drive from Siena to Lyon.
Book your Siena to Lyon bus tickets online with Omio and FlixBus.
What companies run services between Siena, Italy and Lyon, France?
FlixBus operates a bus from Siena to Lyon once daily. Tickets cost €45–85 and the journey takes 12h.
- Website
- easyjet.com
Flights from Fiumicino International Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- €35–150
Flights from Venice Marco Polo Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €29–160
- Website
- swiss.com
Flights from Florence Peretola Airport to Geneva International Airport via Zurich
- Ave. Duration
- 3h 3m
- When
- Every day
- Estimated price
- €75–320
Flights from Florence Peretola Airport to Geneva International Airport via Fiumicino International Airport
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- €75–220
- Website
- lufthansa.com
Flights from Bologna Guglielmo Marconi Airport to Lyon–Saint Exupéry Airport via Frankfurt
- Ave. Duration
- 3h 45m
- When
- Monday, Wednesday, Thursday, Friday, and Saturday
- Estimated price
- €80–140
Flights from Florence Peretola Airport to Geneva International Airport via Munich
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- €120–700
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Geneva International Airport via Zurich
- Ave. Duration
- 3h 7m
- When
- Every day
- Estimated price
- €75–320
Flights from Florence Peretola Airport to Geneva International Airport via Fiumicino International Airport
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- €75–220
- Website
- volotea.com
Flights from Florence Peretola Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Monday and Friday
- Estimated price
- €55–180
Flights from Venice Marco Polo Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 25m
- When
- Thursday and Sunday
- Estimated price
- €24–160
- Website
- twinjet.fr
Flights from Bologna Guglielmo Marconi Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 30m
- When
- Monday to Friday
- Estimated price
- €400–900
- Website
- airdolomiti.it
Flights from Florence Peretola Airport to Geneva International Airport via Munich
- Ave. Duration
- 6h
- When
- Sunday
- Estimated price
- €120–700
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €40–85
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €13–25
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 42m
- Frequency
- Every 30 minutes
- Estimated price
- €35–75
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Venezia Mestre
- Ave. Duration
- 2h 3m
- Frequency
- Hourly
- Estimated price
- €30–70
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Once daily
- Estimated price
- €35–80
- Website
- https://www.italotreno.it/en
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 38 min
- Frequency
- Once daily
- Estimated price
- €11–23
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 3h 54m
- Frequency
- Once daily
- Estimated price
- €30–70
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- €9–21
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- 6 times a week
- Estimated price
- €25–60
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Milano Centrale to Lyon Part Dieu
- Ave. Duration
- 4h 47m
- Frequency
- Twice daily
- Estimated price
- €55–95
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 28m
- Frequency
- Twice daily
- Estimated price
- €11–20
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- 4 times a day
- Estimated price
- €30–55
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Bellegarde to Lyon Part Dieu
- Ave. Duration
- 1h 11m
- Frequency
- Once daily
- Estimated price
- €23–40
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Bellegarde to Lyon Part Dieu
- Ave. Duration
- 1h 27m
- Frequency
- 3 times a week
- Estimated price
- €17–45
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +39 800 142 424
- numeroverdetpl@regione.toscana.it
- Website
- at-bus.it
Bus from Siena-Via Tozzi to Firenze Autostazione
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- https://www.at-bus.it/en
- Schedules at
- https://www.at-bus.it/en/lines-and-timetables
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Siena to Lyon
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- €45–85
- Website
- https://www.flixbus.co.uk
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Florence Villa Constanza Bus Station to Lyon - Perrache Bus Station
- Ave. Duration
- 11h
- Frequency
- 6 times a week
- Estimated price
- €45–85
- Website
- https://www.blablacar.co.uk/bus
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