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How to get fromSafety Harbor to Key Westby plane, bus, ferry, bus (Greyhound), train or car

Find Transport to Key West

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There are 7 ways to get from Safety Harbor to Key West by plane, bus, ferry, bus (Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Tampa

    best
    1. Fly from Tampa (TPA) to Key West International Airport (EYW)plane plane TPA - EYW
    1h 37m
    $154–444

  2. Drive 400.7 mi

    cheapest
    1. Drive from Safety Harbor to Key Westcar car 400.7 mi
    7h 59m
    $74–106

  3. Bus, ferry via Marco Island

    1. Take the bus from Tampa International Airport to Naples, FLbus bus Tampa
    2. Take the ferry from Marco Island, FL to Key West, FLferry ferry Key West
    8h 35m
    $225–360

  4. Bus

    1. Take the bus from Tampa International Airport to Miami Airportbus bus
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus
    3. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    12h 35m
    $92–234

  5. Train, bus

    1. Take the train from Tampa to Delray Beach Amtraktrain train
    2. Take the train from Delray Beach Station to Miami Airport Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    13h 25m
    $108–247

  6. Fly from Saint Petersburg–Clearwater International Airport

    1. Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane plane PIE - EYW
    1h 19m
    $87–408

  7. Bus, ferry

    1. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus FlixBus 2421
    2. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry Fort Myers Beach
    12h 42m
    $196–226

Tampa (TPA) to Key West International Airport (EYW) flights

Calendar12Weekly Planes
Duration2h 22mAverage Duration
Ticket$55Cheapest Price
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Questions & Answers

What companies run services between Safety Harbor, FL, USA and Key West, FL, USA?

Breeze Airways, American Airlines, and Spirit Airlines fly from Tampa (TPA) to Key West International Airport (EYW) twice daily. Alternatively, you can take a vehicle from Safety Harbor to N Roosevelt & 3rd Street via Tampa International Airport, Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 12h 35m.

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