There are 3 ways to get from Fort Myers to Key West by ferry, bus or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.
Ferry • 3h 55m
$129 - $135
2 alternative options
Bus • 9h 25m
Drive • 5h 44m
$29 - $45
Fort Myers to Key West by bus
The bus journey time between Fort Myers and Key West is around 29h 30m and covers a distance of around 362 miles. The fastest bus normally takes 29h 30m. Operated by Greyhound USA and FlixBus-us, the Fort Myers to Key West bus service departs from Ft Myers and arrives in Key West. Typically three buses run weekly, although weekend and holiday schedules can vary so check in advance.
Bus route overview
First and last buses
The schedules shown below are for the next available departures.
Fort Myers to Key West bus schedules
Buses departing Tuesday, August 3, 2021
Buses departing Wednesday, August 4, 2021
Buses departing Thursday, August 5, 2021
Travel safe during COVID-19
Rules to follow in United States
Travel within United States
Domestic border crossings may be subject to approval, testing and quarantine
COVID-19 help in United States
Frequently Asked Questions
Yes, travel within United States is currently allowed.Explore travel options
Domestic travel is not restricted, but some conditions may apply
- Face masks are recommended
- There is a social distancing requirement of 2 metres
- Domestic border crossings may be subject to approval, testing and quarantine
The national COVID-19 helpline number in Key West is 800-232-4636.
Wearing a face mask on public transport in Key West is recommended.
Make yourself known to an official member of staff and/or call the national coronavirus helpline number on 800-232-4636.
Last updated: 28 Jul 2021
Exceptions may apply, for full details: Centers for Disease control and prevention (CDC).
We're working around the clock to bring you the latest COVID-19 travel updates.
This information is compiled from official sources. To the best of our knowledge, it is correct as of the last update.
Visit Rome2rio travel advice for general help.
Questions & Answers
The cheapest way to get from Fort Myers to Key West is to drive which costs $29 - $45 and takes 5h 44m.
The fastest way to get from Fort Myers to Key West is to ferry. Taking this option will cost $125 - $140 and takes 3h 55m.
No, there is no direct bus from Fort Myers to Key West. However, there are services departing from Ft Myers and arriving at Key West via Miami International Airport. The journey, including transfers, takes approximately 9h 25m.
The distance between Fort Myers and Key West is 144 miles. The road distance is 297.1 miles.
The best way to get from Fort Myers to Key West without a car is to ferry which takes 3h 55m and costs $125 - $140.
It takes approximately 3h 55m to get from Fort Myers to Key West, including transfers.
Fort Myers to Key West bus services, operated by Greyhound USA, depart from Ft Myers station.
Fort Myers to Key West bus services, operated by FlixBus-us, arrive at Key West station.
Yes, the driving distance between Fort Myers to Key West is 297 miles. It takes approximately 5h 44m to drive from Fort Myers to Key West.
There are 124+ hotels available in Key West. Prices start at $100 USD per night.
What companies run services between Fort Myers, FL, USA and Key West, FL, USA?
You can take a bus from Fort Myers to Key West via Miami International Airport in around 9h 25m.
Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.
Bus from Ft Myers to Miami
- Ave. Duration
- 5h 5m
- 4 times a week
- Estimated price
- $26 - $40
- $26 - $40
- $45 - $70
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