There are 4 ways to get from Fort Myers to Key West by ferry, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Ferry  •  3 h 54 min

  1. Take the ferry from Fort Myers Beach, FL to Key West, FL Fort Myers Beach - Key West

$143 - $152

Cheapest option

Bus  •  9 h 35 min

  1. Take the bus from Fort Myers, FL to Miami Airport
  2. Take the bus from Miami, Fl to Big Pine Key
  3. Take the bus from Lower Keys Shuttle to Key West, FL - Palm Ave.

$62 - $98

2 alternative options

Drive  •  5 h 46 min

  1. Drive from Fort Myers to Key West 298.9 miles

$29 - $45

Line 140 bus, fly  •  4 h 54 min

  1. Take the line 140 bus from Edison Mall Transfer Station to Bell Tower Shops @ Bell Tower Shops Avenue
  2. Fly from Ft. Myers (RSW) to Key West (EYW) RSW - EYW

$100 - $609

Questions & Answers

The distance between Fort Myers and Key West is 144 miles. The road distance is 298.9 miles.

Get driving directions

The best way to get from Fort Myers to Key West without a car is to ferry which takes 3 h 54 min and costs .

More details

It takes approximately 3 h 54 min to get from Fort Myers to Key West, including transfers.

More details

The quickest flight from Ft. Myers Airport to Key West Airport is the direct flight which takes 55 min.

Search flights

Yes, the driving distance between Fort Myers to Key West is 299 miles. It takes approximately 5 h 46 min to drive from Fort Myers to Key West.

Get driving directions

Silver Airways and American Airlines offer flights from Ft. Myers Airport to Key West Airport.

Search flights

There are 328+ hotels available in Key West. Prices start at $129 USD per night.

More details

Map of how to get from Fort Myers to Key West.
Launch map view
  • Distance: 143.7 miles
  • Duration: 3 h 54 min

What companies run services between Fort Myers, FL, USA and Key West, FL, USA?

You can take a bus from Fort Myers to Key West via Miami Airport, Mia@Lower Level Ramp, Airport Station, Miami, Fl, Big Pine Key, and Lower Keys Shuttle in around 9 h 35 min.

Airlines
Silver Airways
Website
silverairways.com
Flights from Ft. Myers to Key West
Ave. Duration
55 min
When
Every day
Estimated price
$130 - $1,000
American Airlines
Website
aa.com
Flights from Ft. Myers to Key West via Miami
Ave. Duration
2 h 50 min
When
Every day
Estimated price
$210 - $1,100
Bus operators
Javax Bus
Phone
407-299-6360
Email
info@floridatransportation.net
Website
javaxbus.com
Bus from Fort Myers, FL to Miami Airport
Ave. Duration
2 h 25 min
Frequency
Every 3 hours
Estimated price
$40 - $50
Schedules at
javaxbus.com
Book at
gotobus.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Miami, Fl to Big Pine Key
Ave. Duration
3 h 35 min
Frequency
Hourly
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $29
Flexible
$30 - $45
Key West Transit
Phone
(305) 600-1455
Website
kwtransit.com
Bus from Lower Keys Shuttle to Key West, FL - Palm Ave.
Ave. Duration
1 h 4 min
Frequency
Every 4 hours
Estimated price
$2 - $4
Schedules at
cityofkeywest-fl.gov
Lee County Transit
Phone
+1 239-533-2111
Website
rideleetran.com
Bus from Edison Mall Transfer Station to Bell Tower Shops @ Bell Tower Shops Avenue
Ave. Duration
25 min
Frequency
Every 30 minutes
Estimated price
$1 - $3
Schedules at
leegov.com
Ferry operators
Key West Express
Phone
+1 239-463-5733
Website
keywestexpress.net
Ferry from Fort Myers Beach, FL to Key West, FL
Ave. Duration
3 h 30 min
Frequency
Once daily
Estimated price
$95
Book at
Key West Express

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.