• Our partners include:

  • Greyhound USA
  • VIA Rail
  • Amtrak
  • Acela Express
  • Megabus
  • SuperShuttle
  • Booking.com
  • Skyscanner
  • Airbnb
  • Expedia

There are 3 ways to get from Fort Myers to Key West by ferry, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Ferry  •  3h 54m

  1. Take the ferry from Fort Myers Beach, FL to Key West, FL Fort Myers Beach

$143 - $152

Cheapest option

Bus  •  12h 4m

  1. Take the bus from Ft Myers, Fl to Miami, Fl 3749 / ...
  2. Take the bus from Miami, Fl to Key West, Fl 3715 / ...

$48 - $113

1 alternative option

Drive  •  5h 46m

  1. Drive from Fort Myers to Key West 298.9 miles

$29 - $45

Questions & Answers

The cheapest way to get from Fort Myers to Key West is to drive which costs $29 - $45 and takes 5h 46m.

More details

The quickest way to get from Fort Myers to Key West is to ferry which costs $140 - $155 and takes 3h 54m.

More details

No, there is no direct bus from Fort Myers to Key West. However, there are services departing from Ft Myers, Fl and arriving at Flagler & Grinnell via Miami, Fl and Airport/Beaches. The journey, including transfers, takes approximately 12h 4m.

More details

The distance between Fort Myers and Key West is 144 miles. The road distance is 298.9 miles.

Get driving directions

The best way to get from Fort Myers to Key West without a car is to ferry which takes 3h 54m and costs $140 - $155.

More details

It takes approximately 3h 54m to get from Fort Myers to Key West, including transfers.

More details

Fort Myers to Key West bus services, operated by Greyhound USA, depart from Ft Myers, Fl station.

More details

Fort Myers to Key West bus services, operated by Greyhound USA, arrive at Key West, Fl station.

More details

Yes, the driving distance between Fort Myers to Key West is 299 miles. It takes approximately 5h 46m to drive from Fort Myers to Key West.

Get driving directions

There are 338+ hotels available in Key West. Prices start at $165 USD per night.

More details

Map of how to get from Fort Myers to Key West.
Launch map view
  • Distance: 143.7 miles
  • Duration: 3h 54m

What companies run services between Fort Myers, FL, USA and Key West, FL, USA?

You can take a bus from Fort Myers to Key West via Miami, Fl, Key West, Fl, and Airport/Beaches in around 12h 4m.

Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Ft Myers, Fl to Miami, Fl
Ave. Duration
5h 25m
Frequency
5 times a day
Estimated price
$25 - $60
Website
greyhound.com
Economy
$25 - $40
Flexible
$45 - $60
Bus from Miami, Fl to Key West, Fl
Ave. Duration
4h 30m
Frequency
Twice daily
Estimated price
$21 - $50
Website
greyhound.com
Economy
$21 - $35
Flexible
$35 - $50
Ferry operators
Key West Express
Phone
+1 239-463-5733
Website
keywestexpress.net
Ferry from Fort Myers Beach, FL to Key West, FL
Ave. Duration
3h 30m
Frequency
Once daily
Estimated price
$95
Book at
Key West Express

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.