There are 11 ways to get from Rome to Mendrisio by train, bus, car, plane, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Roma Termini to Milano Centraletrain 9950 / ...
- Take the train from Milano Centrale to Mendrisiotrain Re80
4h 39mCHF 81–127Bus to Abruzzo Airport, fly to Milano Malpensa Airport, train
cheapest- Take the bus from Roma, Autostazione Tiburtina to Pescarabus
- Fly from Abruzzo Airport (PSR) to Milano Malpensa Airport (MXP)plane PSR - MXP
- Take the train from Malpensa Aeroporto T1 to Mendrisiotrain
7h 40mCHF 39–221Bus
- Take the bus from Roma Prenestina A1 to Comobus
6h 21mCHF 76–104Drive 627.9 km
- Drive from Rome to Mendrisiocar 627.9 km
6h 2mCHF 106–153Fly Fiumicino International Airport to Milan Linate Airport, train
- Fly from Fiumicino International Airport (FCO) to Milan Linate Airport (LIN)plane FCO - LIN
- Take the train from Monza to Mendrisiotrain
4h 56mCHF 59–184Train via Rome Termini
- Take the train from Roma Termini to Milano Centraletrain Fr / ...
- Take the train from Milano Centrale to Mendrisiotrain Re80
4h 50mCHF 79–145Train via Roma Termini
- Take the train from Roma Termini to Milano Centraletrain 9954 / ...
- Take the train from Milano Centrale to Mendrisiotrain Re80
5h 38mCHF 79–124Fly Fiumicino International Airport to Genoa Cristoforo Colombo Airport, train
- Fly from Fiumicino International Airport (FCO) to Genoa Cristoforo Colombo Airport (GOA)plane FCO - GOA
- Take the train from Genova P.Za Principe to Milano Centraletrain
- Take the train from Milano Centrale to Mendrisiotrain
6h 45mCHF 74–210Fly Fiumicino International Airport to Verona Villafranca Airport, train
- Fly from Fiumicino International Airport (FCO) to Verona Villafranca Airport (VRN)plane FCO - VRN
- Take the train from Verona Porta Nuova to Milano Centraletrain
- Take the train from Milano Centrale to Mendrisiotrain
6h 16mCHF 108–301Fly Fiumicino International Airport to Bologna Guglielmo Marconi Airport, train
- Fly from Fiumicino International Airport (FCO) to Bologna Guglielmo Marconi Airport (BLQ)plane FCO - BLQ
- Take the train from Bologna centrale to Milano Centraletrain
- Take the train from Milano Centrale to Mendrisiotrain
5h 56mCHF 88–229Fly Fiumicino International Airport to Turin Caselle Airport, train
- Fly from Fiumicino International Airport (FCO) to Turin Caselle Airport (TRN)plane FCO - TRN
- Take the train from Torino Porta di Susa to Milano Centraletrain
- Take the train from Milano Centrale to Mendrisiotrain
6h 49mCHF 53–227
Rome to Mendrisio by train
Comparing Your Travel Options
The cheapest way to get from Rome to Mendrisio is to bus and fly and train which costs SFr 35 - SFr 230 and takes 7h 40m.
The fastest way to get from Rome to Mendrisio is to train which takes 4h 39m and costs SFr 80 - SFr 130.
No, there is no direct bus from Rome to Mendrisio. However, there are services departing from Roma Prenestina A1 and arriving at Mendrisio, Autosilo via Como - Chiesa di San Zenone and Chiasso, Stazione. The journey, including transfers, takes approximately 6h 21m.
No, there is no direct train from Rome to Mendrisio. However, there are services departing from Roma Termini and arriving at Mendrisio via Milano Centrale. The journey, including transfers, takes approximately 4h 39m.
The distance between Rome and Mendrisio is 639 km. The road distance is 627.9 km.
The best way to get from Rome to Mendrisio without a car is to train which takes 4h 39m and costs SFr 80 - SFr 130.
It takes approximately 4h 39m to get from Rome to Mendrisio, including transfers.
Rome to Mendrisio bus services, operated by Onebus, depart from Roma Prenestina A1 station.
Rome to Mendrisio train services, operated by ItaloTreno, depart from Roma Termini station.
The best way to get from Rome to Mendrisio is to train which takes 4h 39m and costs SFr 80 - SFr 130. Alternatively, you can bus, which costs SFr 75 - SFr 110 and takes 6h 21m.
What companies run services between Rome, Italy and Mendrisio, Switzerland?
You can take a train from Roma Termini to Mendrisio via Milano Centrale in around 4h 39m. Alternatively, Onebus operates a bus from Roma Prenestina A1 to Como once a week. Tickets cost CHF 70–100 and the journey takes 5h 23m.
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Milan Linate Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- CHF 50–170
Flights from Fiumicino International Airport to Genoa Cristoforo Colombo Airport
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- CHF 45–150
Flights from Fiumicino International Airport to Verona Villafranca Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- CHF 55–210
Flights from Fiumicino International Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 3m
- When
- Every day
- Estimated price
- CHF 55–130
Flights from Fiumicino International Airport to Turin Caselle Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- CHF 70–170
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 5m
- Frequency
- Hourly
- Estimated price
- CHF 65–110
- Website
- Italo Treno
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 15m
- Frequency
- 4 times a day
- Estimated price
- CHF 60–100
- Website
- Italo Treno
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 4h 4m
- Frequency
- 4 times a day
- Estimated price
- CHF 60–100
- Website
- Italo Treno
Train from Bologna centrale to Milano Centrale
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- CHF 23–40
- Website
- Italo Treno
Train from Torino Porta di Susa to Milano Centrale
- Ave. Duration
- 50 min
- Frequency
- Every 4 hours
- Estimated price
- CHF 15–25
- Website
- Italo Treno
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- Onebus
Bus from Roma Prenestina A1 to Como
- Ave. Duration
- 5h 23m
- Frequency
- Once a week
- Estimated price
- CHF 70–100
- Website
- Onebus
Want to know more about travelling around Switzerland
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Booking & Getting There
Rome to Mendrisio bus services, operated by Onebus, arrive at Como station.
Rome to Mendrisio train services, operated by ItaloTreno, arrive at Milano Centrale station.
Yes, the driving distance between Rome to Mendrisio is 628 km. It takes approximately 6h 2m to drive from Rome to Mendrisio.
There are 5536+ hotels available in Mendrisio.