There are 8 ways to get from Charlotte to Key Largo by plane, shuttle, bus (Flixbus, Greyhound), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Charlotte Douglas International Airport to Miami International Airport, shuttle
best- Fly from Charlotte Douglas International Airport (CLT) to Miami International Airport (MIA)plane CLT - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
5h 52m$127–352Bus
cheapest- Take the bus from Charlotte Bus Station to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
18h 20m$104–242Bus, train
- Take the bus from Charlotte Bus Station to Fayetteville Bus Stationbus
- Take the train from Fayetteville Amtrak Station to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
25h 1m$118–351Drive 785.8 mi
- Drive from Charlotte to Key Largocar 785.8 mi
13h 8m$144–208Fly Charlotte Douglas International Airport to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Charlotte Douglas International Airport (CLT) to Fort Lauderdale–Hollywood International Airport (FLL)plane CLT - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
6h 15m$152–372Fly Charlotte Douglas International Airport to Key West International Airport, bus
- Fly from Charlotte Douglas International Airport (CLT) to Key West International Airport (EYW)plane CLT - EYW
- Take the bus from Key West Airport to Key Largo Bus Stopbus
7h 24m$141–562Bus to Greenville–Spartanburg International Airport, fly to Miami International Airport, shuttle
- Take the bus from Charlotte, NC to Greenville, SCbus
- Fly from Greenville–Spartanburg International Airport (GSP) to Miami International Airport (MIA)plane GSP - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
6h 56m$235–693Train, bus
- Take the train from Charlotte Amtrak Station to Carytrain
- Take the train from Cary to Miami Amtrak Stationtrain
- Take the bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largobus 301
29h 40m
Charlotte to Key Largo by bus
Questions & Answers
The cheapest way to get from Charlotte to Key Largo is to bus which costs $100 - $250 and takes 18h 20m.
The fastest way to get from Charlotte to Key Largo is to fly and shuttle which takes 5h 52m and costs $120 - $360.
No, there is no direct bus from Charlotte station to Key Largo. However, there are services departing from Charlotte Bus Station and arriving at Key Largo Bus Stop via Orlando Bus Station and Miami Airport Station. The journey, including transfers, takes approximately 18h 20m.
The distance between Charlotte and Key Largo is 721 miles. The road distance is 790.3 miles.
The best way to get from Charlotte to Key Largo without a car is to bus which takes 18h 20m and costs $100 - $250.
It takes approximately 5h 52m to get from Charlotte to Key Largo, including transfers.
Charlotte to Key Largo bus services, operated by Flixbus USA, depart from Charlotte Bus Station.
Charlotte to Key Largo bus services, operated by Flixbus USA, arrive at Orlando Bus Station.
Yes, the driving distance between Charlotte to Key Largo is 790 miles. It takes approximately 13h 8m to drive from Charlotte to Key Largo.
Book your Charlotte to Key Largo bus tickets online with Omio and FlixBus.
What companies run services between Charlotte, NC, USA and Key Largo, FL, USA?
You can take a bus from Charlotte Bus Station to Key Largo Bus Stop via Orlando Bus Station and Miami Airport Station in around 18h 20m.
- Website
- aa.com
Flights from Charlotte Douglas International Airport to Miami International Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- $60–340
Flights from Charlotte Douglas International Airport to Miami International Airport via Gainesville
- Ave. Duration
- 3h 38m
- When
- Saturday
- Estimated price
- $60–350
Flights from Charlotte Douglas International Airport to Miami International Airport via Jacksonville
- Ave. Duration
- 3h 57m
- When
- Saturday
- Estimated price
- $60–350
Flights from Charlotte Douglas International Airport to Miami International Airport via Tampa
- Ave. Duration
- 4h 9m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $60–360
Flights from Charlotte Douglas International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $40–250
Flights from Charlotte Douglas International Airport to Key West International Airport
- Ave. Duration
- 2h 21m
- When
- Every day
- Estimated price
- $85–490
Flights from Charlotte Douglas International Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $90–490
Flights from Greenville–Spartanburg International Airport to Miami International Airport
- Ave. Duration
- 2h 3m
- When
- Every day
- Estimated price
- $80–480
Flights from Greenville–Spartanburg International Airport to Miami International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $90–500
- Website
- delta.com
Flights from Charlotte Douglas International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $95–550
Flights from Greenville–Spartanburg International Airport to Miami International Airport via Atlanta
- Ave. Duration
- 4h 49m
- When
- Every day
- Estimated price
- $90–550
- Website
- spirit.com
Flights from Charlotte Douglas International Airport to Miami International Airport
- Ave. Duration
- 2h 10m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $45–240
Flights from Charlotte Douglas International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 6m
- When
- Every day
- Estimated price
- $50–230
- Website
- flyfrontier.com
Flights from Charlotte Douglas International Airport to Miami International Airport
- Ave. Duration
- 2h 19m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $60–340
Flights from Charlotte Douglas International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 10m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $40–250
- Website
- southwest.com
Flights from Greenville–Spartanburg International Airport to Miami International Airport via Nashville
- Ave. Duration
- 4h 35m
- When
- Saturday
- Estimated price
- $110–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Fayetteville Amtrak Station to Hollywood Amtrak Station
- Ave. Duration
- 16h 54m
- Frequency
- Once daily
- Estimated price
- $75–250
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $75–200
- Coach Seat short notice purchase
- $100–250
- Business - advance purchase
- $140–600
- Business Class
- $220–600
Train from Charlotte Amtrak Station to Cary
- Ave. Duration
- 3h 1m
- Frequency
- 5 times a day
- Estimated price
- $30–45
- Website
- https://www.amtrak.com/home.html
Train from Cary to Miami Amtrak Station
- Ave. Duration
- 21h 58m
- Frequency
- Once daily
- Estimated price
- $75–250
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $80–110
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $100–140
- Website
- https://www.keysshuttle.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Charlotte Bus Station to Orlando Bus Station
- Ave. Duration
- 10h 15m
- Frequency
- Twice daily
- Estimated price
- $60–170
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 4h 50m
- Frequency
- Hourly
- Estimated price
- $28–60
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $28–55
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- 3 times a day
- Estimated price
- $14–21
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Fayetteville Bus Station
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $26–75
- Website
- https://www.greyhound.com/
Bus from Key West Airport to Key Largo Bus Stop
- Ave. Duration
- 2h 40m
- Frequency
- 3 times a day
- Estimated price
- $29–60
- Website
- https://www.greyhound.com/
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- wandacoach.com
Bus from Charlotte, NC to Greenville, SC
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $35–55
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Phone
- +1 786-469-5675
- Website
- miamidade.gov
Bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largo
- Ave. Duration
- 55 min
- Frequency
- Hourly
- Website
- https://www.miamidade.gov/global/transportation/home.page
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