Rome2Rio

How to get fromPoplar Bluff to Chicagoby car, plane, taxi, bus, train (Amtrak) or train

Find Transport to Chicago

See all options

There are 8 ways to get from Poplar Bluff to Chicago by car, plane, taxi, bus, train (Amtrak), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Cape Girardeau Municipal Airport, fly to Chicago O'Hare International Airport

    best
    1. Drive from Poplar Bluff to Cape Girardeau Municipal Airport (CGI)car car
    2. Fly from Cape Girardeau Municipal Airport (CGI) to Chicago O'Hare International Airport (ORD)plane plane CGI - ORD
    3h 59m
    $80–193

  2. Train (Amtrak)

    cheapest
    1. Take the train from Poplar Bluff Station to Chicago Union Stationtrain train Texas Eagle
    11h
    $45–200

  3. Taxi, bus

    1. Take the taxi from Poplar Bluff to Flying J - Matthewstaxi taxi
    2. Take the bus from Flying J - Matthews to Tornado Bus Co - Chicagobus bus Milwaukee
    9h 13m
    $192–328

  4. Drive 441.4 mi

    1. Drive from Poplar Bluff to Chicagocar car 441.4 mi
    7h 16m
    $81–117

  5. Drive to Barkley Regional Airport, fly to Chicago O'Hare International Airport

    1. Drive from Poplar Bluff to Barkley Regional Airport (PAH)car car
    2. Fly from Barkley Regional Airport (PAH) to Chicago O'Hare International Airport (ORD)plane plane PAH - ORD
    4h 29m
    $201–1,632

  6. Train to Lambert–St. Louis International Airport, fly to Chicago Midway International Airport

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane plane STL - MDW
    8h 15m
    $105–547

  7. Train to Lambert–St. Louis International Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Poplar Bluff Station to St. Louistrain train
    2. Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane plane STL - ORD
    8h 38m
    $230–547

  8. Train, bus

    1. Take the train from Poplar Bluff Station to St. Louistrain train Texas Eagle
    2. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus N2521 / ...
    12h 1m
    $60–114

Poplar Bluff to Chicago by train (Amtrak)

Calendar10Weekly Trains
Duration11hAverage Duration
Ticket$45Cheapest Price
See schedules

Questions & Answers

What companies run services between Poplar Bluff, MO, USA and Chicago, IL, USA?

Amtrak operates a train from Poplar Bluff Station to Chicago Union Station once daily. Tickets cost $45–200 and the journey takes 11h.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

More Questions & Answers

Where to next?

Trips from Poplar Bluff

Trips to Chicago

Popular routes