There are 8 ways to get from Pittsburgh to Santa Ana by plane, train (Amtrak), bus (Greyhound), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to John Wayne Airport Orange County
best- Fly from Pittsburgh International Airport (PIT) to John Wayne Airport Orange County (SNA)plane PIT - SNA
9h 7m$274–1,034Fly to Long Beach Airport
cheapest- Fly from Pittsburgh International Airport (PIT) to Long Beach Airport (LGB)plane PIT - LGB
12h 2m$170–679Train (Amtrak)
- Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain Floridian
- Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain Southwest Chief
2d 6h$679–1,580Bus
- Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to El Monte Bus Stopbus
- Take the bus from El Monte to Santa Anabus
2d 8h$409–659Drive 2,410.2 mi
- Drive from Pittsburgh to Santa Anacar 2,410.2 mi
38h 39m$440–636Fly to Los Angeles International Airport, train
- Fly from Pittsburgh International Airport (PIT) to Los Angeles International Airport (LAX)plane PIT - LAX
- Take the train from Los Angeles to Santa Anatrain
10h 4m$205–456Fly to San Diego International Airport, train
- Fly from Pittsburgh International Airport (PIT) to San Diego International Airport (SAN)plane PIT - SAN
- Take the train from San Diego to Santa Anatrain
10h 39m$180–601Bus, train
- Take the bus from Pittsburgh Intermodal Station to Chicagobus FlixBus N2640
- Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain Southwest Chief
2d 9h$639–1,428
Pittsburgh to Santa Ana by train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Pittsburgh to Santa Ana is to fly and train which costs $200 - $460 and takes 10h 4m.
The fastest way to get from Pittsburgh to Santa Ana is to fly which takes 9h 7m and costs $270 - $1,100.
No, there is no direct bus from Pittsburgh station to Santa Ana. However, there are services departing from Pittsburgh Intermodal Station and arriving at Santa Ana via St Louis Bus Station, El Monte Station Upper Level and El Monte. The journey, including transfers, takes approximately 2 days 8h.
No, there is no direct train from Pittsburgh station to Santa Ana. However, there are services departing from Pittsburgh Amtrak Station and arriving at Santa Ana via Chicago Union Station and Fullerton Amtrak Station. The journey, including transfers, takes approximately 2 days 6h.
The distance between Pittsburgh and Santa Ana is 2152 miles. The road distance is 2424.3 miles.
The best way to get from Pittsburgh to Santa Ana without a car is to train which takes 2 days 6h and costs $650 - $1,600.
It takes approximately 9h 7m to get from Pittsburgh to Santa Ana, including transfers.
Pittsburgh to Santa Ana bus services, operated by Greyhound USA, depart from Pittsburgh Intermodal Station.
Pittsburgh to Santa Ana train services, operated by Amtrak, depart from Pittsburgh Amtrak Station.
The best way to get from Pittsburgh to Santa Ana is to fly which takes 9h 7m and costs $270 - $1,100. Alternatively, you can train, which costs $650 - $1,600 and takes 2 days 6h, you could also bus, which costs $400 - $700 and takes 2 days 8h.
What companies run services between Pittsburgh, PA, USA and Santa Ana, CA, USA?
Southwest Airlines, United Airlines, and two other airlines fly from Pittsburgh International Airport (PIT) to John Wayne Airport Orange County (SNA) every 3 hours. Alternatively, you can take a train from Pittsburgh Amtrak Station to Santa Ana via Chicago Union Station and Fullerton Amtrak Station in around 2d 6h.
- Website
- southwest.com
Flights from Pittsburgh International Airport to John Wayne Airport Orange County via Las Vegas
- Ave. Duration
- 6h 50m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $240–1,000
Flights from Pittsburgh International Airport to John Wayne Airport Orange County via Dallas
- Ave. Duration
- 8h 7m
- When
- Saturday and Sunday
- Estimated price
- $250–1,100
Flights from Pittsburgh International Airport to John Wayne Airport Orange County via Phoenix
- Ave. Duration
- 8h 23m
- When
- Every day
- Estimated price
- $240–1,000
Flights from Pittsburgh International Airport to John Wayne Airport Orange County via Denver
- Ave. Duration
- 8h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $240–1,000
Flights from Pittsburgh International Airport to John Wayne Airport Orange County via Austin
- Ave. Duration
- 7h 55m
- When
- Sunday, Tuesday, and Wednesday
- Estimated price
- $270–1,100
Flights from Pittsburgh International Airport to Los Angeles International Airport via St. Louis
- Ave. Duration
- 6h 30m
- When
- Sunday, Tuesday, and Wednesday
- Estimated price
- $150–650
Flights from Pittsburgh International Airport to Los Angeles International Airport via Las Vegas
- Ave. Duration
- 7h 2m
- When
- Sunday
- Estimated price
- $150–650
Flights from Pittsburgh International Airport to Los Angeles International Airport via Denver
- Ave. Duration
- 7h 20m
- When
- Every day
- Estimated price
- $150–650
Flights from Pittsburgh International Airport to Los Angeles International Airport via Phoenix
- Ave. Duration
- 7h 10m
- When
- Saturday
- Estimated price
- $150–650
Flights from Pittsburgh International Airport to San Diego International Airport
- Ave. Duration
- 4h 55m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $190–800
Flights from Pittsburgh International Airport to San Diego International Airport via Phoenix
- Ave. Duration
- 6h 56m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $190–800
Flights from Pittsburgh International Airport to San Diego International Airport via St. Louis
- Ave. Duration
- 6h 35m
- When
- Sunday
- Estimated price
- $190–800
Flights from Pittsburgh International Airport to San Diego International Airport via Denver
- Ave. Duration
- 7h 11m
- When
- Every day
- Estimated price
- $190–850
Flights from Pittsburgh International Airport to San Diego International Airport via Las Vegas
- Ave. Duration
- 6h 50m
- When
- Tuesday, Wednesday, Sunday, and Saturday
- Estimated price
- $200–850
Flights from Pittsburgh International Airport to San Diego International Airport via Chicago Midway
- Ave. Duration
- 7h 55m
- When
- Every day
- Estimated price
- $190–850
Flights from Pittsburgh International Airport to Long Beach Airport via Las Vegas
- Ave. Duration
- 6h 57m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–700
Flights from Pittsburgh International Airport to Long Beach Airport via Denver
- Ave. Duration
- 8h 35m
- When
- Saturday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $160–700
Flights from Pittsburgh International Airport to Long Beach Airport via Phoenix
- Ave. Duration
- 7h 5m
- When
- Saturday
- Estimated price
- $160–700
Flights from Pittsburgh International Airport to Long Beach Airport via Dallas
- Ave. Duration
- 7h 25m
- When
- Saturday
- Estimated price
- $170–700
Flights from Pittsburgh International Airport to Long Beach Airport via Chicago Midway
- Ave. Duration
- 7h 50m
- When
- Every day
- Estimated price
- $160–700
Flights from Pittsburgh International Airport to Long Beach Airport via Austin
- Ave. Duration
- 7h 50m
- When
- Monday, Thursday, and Friday
- Estimated price
- $180–750
Flights from Pittsburgh International Airport to Long Beach Airport via Nashville
- Ave. Duration
- 10h 58m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $170–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Chicago Union Station
- Ave. Duration
- 9h 46m
- Frequency
- Once daily
- Estimated price
- $120–280
- Website
- Amtrak
Train from Chicago Union Station to Fullerton Amtrak Station
- Ave. Duration
- 42h 44m
- Frequency
- Once daily
- Estimated price
- $550–1,300
- Website
- Amtrak
Train from Los Angeles to Santa Ana
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $9–20
- Website
- Amtrak
Train from San Diego to Santa Ana
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- $23–55
- Website
- Amtrak
Train from Chicago Union Station to Fullerton Amtrak Station
- Ave. Duration
- 42h 44m
- Frequency
- Once daily
- Estimated price
- $550–1,300
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Pittsburgh Intermodal Station to St Louis Bus Station
- Ave. Duration
- 12h 55m
- Frequency
- 3 times a day
- Estimated price
- $90–150
- Website
- Greyhound
Bus from St Louis Bus Station to El Monte Bus Stop
- Ave. Duration
- 40h 10m
- Frequency
- Once daily
- Estimated price
- $290–470
- Website
- Greyhound
Want to know more about travelling around United States
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Booking & Getting There
Pittsburgh to Santa Ana bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Santa Ana is 3h behind Pittsburgh. It is currently 4:27 PM in Pittsburgh and 1:27 PM in Santa Ana.
Pittsburgh to Santa Ana train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Pittsburgh to Santa Ana is 2424 miles. It takes approximately 38h 39m to drive from Pittsburgh to Santa Ana.
Book your Pittsburgh to Santa Ana train tickets online with Omio.
Book your Pittsburgh to Santa Ana bus tickets online with Omio.
There are 1495+ hotels available in Santa Ana.





