Rome2Rio

How to get fromPittsburgh to Santa Anaby plane, train (Amtrak), bus (Greyhound, Amtrak), car, train or bus

Find Transport to Santa Ana

See all options

There are 9 ways to get from Pittsburgh to Santa Ana by plane, train (Amtrak), bus (Greyhound, Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to John Wayne Airport Orange County

    best
    1. Fly from Pittsburgh International Airport (PIT) to John Wayne Airport Orange County (SNA)plane plane PIT - SNA
    9h 31m
    $184–566

  2. Fly to Los Angeles International Airport, train

    cheapest
    1. Fly from Pittsburgh International Airport (PIT) to Los Angeles International Airport (LAX)plane plane PIT - LAX
    2. Take the train from L.A. Union Station to Santa Anatrain train
    10h 50m
    $166–463

  3. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train Southwest Chief
    2d 6h
    $267–1,700

  4. Bus

    1. Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    3. Take the bus from Los Angeles to Santa Anabus bus
    2d 6h

  5. Drive 2,404.4 mi

    1. Drive from Pittsburgh to Santa Anacar car 2,404.4 mi
    38h 49m
    $439–634

  6. Fly to San Diego International Airport, train

    1. Fly from Pittsburgh International Airport (PIT) to San Diego International Airport (SAN)plane plane PIT - SAN
    2. Take the train from San Diego Old Town Transportation Center to Santa Anatrain train
    10h 30m
    $582–751

  7. Fly to Long Beach Airport

    1. Fly from Pittsburgh International Airport (PIT) to Long Beach Airport (LGB)plane plane PIT - LGB
    12h 57m
    $183–745

  8. Fly to Burbank Bob Hope Airport, train

    1. Fly from Pittsburgh International Airport (PIT) to Burbank Bob Hope Airport (BUR)plane plane PIT - BUR
    2. Take the train from L.A. Union Station to Santa Anatrain train
    13h 4m
    $178–707

  9. Bus, train

    1. Take the bus from Pittsburgh Intermodal Station to Chicagobus bus FlixBus N2640
    2. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train Southwest Chief
    2d 8h
    $271–1,614

Pittsburgh to Santa Ana by train (Amtrak)

Calendar7Weekly Trains
Duration2d 6hAverage Duration
Ticket$267Cheapest Price
See schedules

Questions & Answers

What companies run services between Pittsburgh, PA, USA and Santa Ana, CA, USA?

American Airlines, Southwest Airlines, and two other airlines fly from Pittsburgh International Airport (PIT) to John Wayne Airport Orange County (SNA) every 2 hours. Alternatively, you can take a train from Pittsburgh Amtrak Station to Santa Ana via Chicago Union Station and Fullerton Amtrak Station in around 2d 6h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Trips from Pittsburgh

Trips to Santa Ana

Popular routes