There are 8 ways to get from Pittsburgh to Santa Ana by plane, train (Amtrak), bus (Greyhound, Amtrak), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to John Wayne Airport Orange County
best- Fly from Pittsburgh International Airport (PIT) to John Wayne Airport Orange County (SNA)plane PIT - SNA
9h 2m$447–591Fly to Los Angeles International Airport, train
cheapest- Fly from Pittsburgh International Airport (PIT) to Los Angeles International Airport (LAX)plane PIT - LAX
- Take the train from Los Angeles to Santa Anatrain
10h 11m$188–709Train (Amtrak)
- Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain Floridian
- Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain Southwest Chief
2d 6h$742–1,702Bus
- Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Los Angeles Union Stationbus
- Take the bus from Los Angeles to Santa Anabus
2d 8h$421–860Drive 2,404.4 mi
- Drive from Pittsburgh to Santa Anacar 2,404.4 mi
38h 53m$439–634Fly to San Diego International Airport, train
- Fly from Pittsburgh International Airport (PIT) to San Diego International Airport (SAN)plane PIT - SAN
- Take the train from San Diego to Santa Anatrain
10h 42m$301–1,237Fly to Long Beach Airport
- Fly from Pittsburgh International Airport (PIT) to Long Beach Airport (LGB)plane PIT - LGB
12h 3m$218–925Bus, train
- Take the bus from Pittsburgh Intermodal Station to Chicagobus FlixBus N2640
- Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain Southwest Chief
2d 9h$682–1,529
Pittsburgh to Santa Ana by train (Amtrak)
Questions & Answers
The cheapest way to get from Pittsburgh to Santa Ana is to fly and train which costs $180 - $750 and takes 10h 11m.
The fastest way to get from Pittsburgh to Santa Ana is to fly which takes 9h 2m and costs $440 - $600.
No, there is no direct bus from Pittsburgh station to Santa Ana. However, there are services departing from Pittsburgh Intermodal Station and arriving at Santa Ana via St Louis Bus Station and Los Angeles. The journey, including transfers, takes approximately 2 days 8h.
No, there is no direct train from Pittsburgh station to Santa Ana. However, there are services departing from Pittsburgh Amtrak Station and arriving at Santa Ana via Chicago Union Station and Fullerton Amtrak Station. The journey, including transfers, takes approximately 2 days 6h.
The distance between Pittsburgh and Santa Ana is 2152 miles. The road distance is 2418.5 miles.
The best way to get from Pittsburgh to Santa Ana without a car is to train which takes 2 days 6h and costs $700 - $1,700.
It takes approximately 9h 2m to get from Pittsburgh to Santa Ana, including transfers.
Pittsburgh to Santa Ana bus services, operated by Greyhound USA, depart from Pittsburgh Intermodal Station.
Pittsburgh to Santa Ana train services, operated by Amtrak, depart from Pittsburgh Amtrak Station.
The best way to get from Pittsburgh to Santa Ana is to fly which takes 9h 2m and costs $440 - $600. Alternatively, you can train, which costs $700 - $1,700 and takes 2 days 6h, you could also bus, which costs $420 - $900 and takes 2 days 8h.
What companies run services between Pittsburgh, PA, USA and Santa Ana, CA, USA?
Southwest Airlines, Delta, and two other airlines fly from Pittsburgh International Airport (PIT) to John Wayne Airport Orange County (SNA) every 2 hours. Alternatively, you can take a train from Pittsburgh Amtrak Station to Santa Ana via Chicago Union Station and Fullerton Amtrak Station in around 2d 6h.
- Website
- southwest.com
Flights from Pittsburgh International Airport to John Wayne Airport Orange County via Phoenix
- Ave. Duration
- 7h 8m
- When
- Saturday, Monday, Thursday, and Friday
- Estimated price
- $260–1,200
Flights from Pittsburgh International Airport to John Wayne Airport Orange County via Denver
- Ave. Duration
- 6h 53m
- When
- Monday to Wednesday
- Estimated price
- $260–1,200
Flights from Pittsburgh International Airport to John Wayne Airport Orange County via Las Vegas
- Ave. Duration
- 7h 52m
- When
- Every day
- Estimated price
- $260–1,200
Flights from Pittsburgh International Airport to John Wayne Airport Orange County via Dallas
- Ave. Duration
- 7h 30m
- When
- Saturday, Monday, Thursday, and Friday
- Estimated price
- $280–1,200
Flights from Pittsburgh International Airport to John Wayne Airport Orange County via Austin
- Ave. Duration
- 10h 45m
- When
- Monday to Wednesday
- Estimated price
- $290–1,300
Flights from Pittsburgh International Airport to Los Angeles International Airport via St. Louis
- Ave. Duration
- 6h 40m
- When
- Monday to Wednesday
- Estimated price
- $160–750
Flights from Pittsburgh International Airport to Los Angeles International Airport via Denver
- Ave. Duration
- 6h 46m
- When
- Monday to Wednesday
- Estimated price
- $170–750
Flights from Pittsburgh International Airport to Los Angeles International Airport via Chicago Midway
- Ave. Duration
- 6h 48m
- When
- Every day
- Estimated price
- $170–750
Flights from Pittsburgh International Airport to Los Angeles International Airport via Phoenix
- Ave. Duration
- 6h 51m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $170–750
Flights from Pittsburgh International Airport to Los Angeles International Airport via Dallas
- Ave. Duration
- 7h 5m
- When
- Saturday
- Estimated price
- $180–800
Flights from Pittsburgh International Airport to San Diego International Airport
- Ave. Duration
- 4h 55m
- When
- Monday, Thursday, and Friday
- Estimated price
- $270–1,200
Flights from Pittsburgh International Airport to San Diego International Airport via Chicago Midway
- Ave. Duration
- 6h 40m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $270–1,200
Flights from Pittsburgh International Airport to San Diego International Airport via St. Louis
- Ave. Duration
- 6h 40m
- When
- Monday to Friday
- Estimated price
- $270–1,200
Flights from Pittsburgh International Airport to San Diego International Airport via Las Vegas
- Ave. Duration
- 6h 47m
- When
- Monday, Thursday, and Friday
- Estimated price
- $270–1,200
Flights from Pittsburgh International Airport to San Diego International Airport via Denver
- Ave. Duration
- 6h 50m
- When
- Every day
- Estimated price
- $270–1,200
Flights from Pittsburgh International Airport to San Diego International Airport via Phoenix
- Ave. Duration
- 6h 57m
- When
- Sunday, Saturday, Monday, Thursday, and Friday
- Estimated price
- $270–1,200
Flights from Pittsburgh International Airport to Long Beach Airport via Chicago Midway
- Ave. Duration
- 7h 32m
- When
- Monday to Wednesday
- Estimated price
- $210–950
Flights from Pittsburgh International Airport to Long Beach Airport via Denver
- Ave. Duration
- 6h 53m
- When
- Monday to Wednesday
- Estimated price
- $210–950
Flights from Pittsburgh International Airport to Long Beach Airport via Dallas
- Ave. Duration
- 7h 7m
- When
- Saturday, Monday, Thursday, and Friday
- Estimated price
- $220–1,000
Flights from Pittsburgh International Airport to Long Beach Airport via Phoenix
- Ave. Duration
- 7h 12m
- When
- Monday, Thursday, and Friday
- Estimated price
- $210–950
Flights from Pittsburgh International Airport to Long Beach Airport via Las Vegas
- Ave. Duration
- 8h 9m
- When
- Sunday, Saturday, Tuesday, and Wednesday
- Estimated price
- $210–950
Flights from Pittsburgh International Airport to Long Beach Airport via Nashville
- Ave. Duration
- 8h 32m
- When
- Monday, Thursday, and Friday
- Estimated price
- $220–950
Flights from Pittsburgh International Airport to Long Beach Airport via Austin
- Ave. Duration
- 10h 45m
- When
- Monday, Thursday, and Friday
- Estimated price
- $230–1,100
- Website
- delta.com
Flights from Pittsburgh International Airport to John Wayne Airport Orange County via Detroit
- Ave. Duration
- 7h 13m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $260–1,200
Flights from Pittsburgh International Airport to John Wayne Airport Orange County via Salt Lake City
- Ave. Duration
- 7h 14m
- When
- Every day
- Estimated price
- $270–1,200
Flights from Pittsburgh International Airport to John Wayne Airport Orange County via Minneapolis
- Ave. Duration
- 9h 5m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $270–1,200
Flights from Pittsburgh International Airport to Long Beach Airport via Salt Lake City
- Ave. Duration
- 7h 3m
- When
- Every day
- Estimated price
- $220–950
- Website
- united.com
Flights from Pittsburgh International Airport to John Wayne Airport Orange County via Denver
- Ave. Duration
- 7h 18m
- When
- Every day
- Estimated price
- $260–1,200
Flights from Pittsburgh International Airport to Los Angeles International Airport
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $160–750
- Website
- aa.com
Flights from Pittsburgh International Airport to John Wayne Airport Orange County via Phoenix
- Ave. Duration
- 7h 17m
- When
- Every day
- Estimated price
- $260–1,200
Flights from Pittsburgh International Airport to Los Angeles International Airport
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $160–750
- Website
- flybreeze.com
Flights from Pittsburgh International Airport to Los Angeles International Airport
- Ave. Duration
- 5h 19m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $160–750
Flights from Pittsburgh International Airport to San Diego International Airport
- Ave. Duration
- 5h 13m
- When
- Monday and Friday
- Estimated price
- $330–1,900
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Pittsburgh Amtrak Station to Chicago Union Station
- Ave. Duration
- 9h 46m
- Frequency
- Once daily
- Estimated price
- $130–300
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Fullerton Amtrak Station
- Ave. Duration
- 42h 44m
- Frequency
- Once daily
- Estimated price
- $600–1,400
- Website
- https://www.amtrak.com/home.html
Train from Los Angeles to Santa Ana
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $9–22
- Website
- https://www.amtrak.com/home.html
Train from San Diego to Santa Ana
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- $26–60
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Pittsburgh Intermodal Station to St Louis Bus Station
- Ave. Duration
- 12h 55m
- Frequency
- 3 times a day
- Estimated price
- $100–200
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Los Angeles Union Station
- Ave. Duration
- 40h 30m
- Frequency
- Once daily
- Estimated price
- $310–650
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Los Angeles to Santa Ana
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $11–18
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Pittsburgh Intermodal Station to Chicago
- Ave. Duration
- 10h 55m
- Frequency
- Once daily
- Estimated price
- $70–120
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Pittsburgh to Santa Ana bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Santa Ana is 3h behind Pittsburgh. It is currently 4:58 AM in Pittsburgh and 1:58 AM in Santa Ana.
Pittsburgh to Santa Ana train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Pittsburgh to Santa Ana is 2418 miles. It takes approximately 38h 53m to drive from Pittsburgh to Santa Ana.
Book your Pittsburgh to Santa Ana train tickets online with Omio.
Book your Pittsburgh to Santa Ana bus tickets online with Omio.
There are 1350+ hotels available in Santa Ana.






