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How to get fromPittsburgh to Santa Anaby plane, train (Amtrak), bus (Greyhound), car, train, or bus

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There are 10 ways to get from Pittsburgh to Santa Ana by plane, train (Amtrak), bus (Greyhound), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Pittsburgh International Airport to John Wayne Airport Orange County

    best
    1. Fly from Pittsburgh International Airport (PIT) to John Wayne Airport Orange County (SNA)plane plane PIT - SNA
    10h 9m
    $223–927

  2. Fly Pittsburgh International Airport to Ontario International Airport, train

    cheapest
    1. Fly from Pittsburgh International Airport (PIT) to Ontario International Airport (ONT)plane plane PIT - ONT
    2. Take the train from San Bernardino Depot to Santa Anatrain train
    13h 14m
    $197–796

  3. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train Southwest Chief
    2d 6h
    $1,469–2,312

  4. Bus

    1. Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to El Monte Bus Stopbus bus
    3. Take the bus from El Monte to Santa Anabus bus
    2d 8h
    $475–703

  5. Drive  2,410 mi

    1. Drive from Pittsburgh to Santa Anacar car 2,410 mi
    38h 40m
    $398–575

  6. Fly Pittsburgh International Airport to Los Angeles International Airport, train

    1. Fly from Pittsburgh International Airport (PIT) to Los Angeles International Airport (LAX)plane plane PIT - LAX
    2. Take the train from Los Angeles to Santa Anatrain train
    10h 14m
    $242–466

  7. Fly Pittsburgh International Airport to San Diego International Airport, train

    1. Fly from Pittsburgh International Airport (PIT) to San Diego International Airport (SAN)plane plane PIT - SAN
    2. Take the train from San Diego to Santa Anatrain train
    10h 53m
    $239–871

  8. Fly Pittsburgh International Airport to Long Beach Airport

    1. Fly from Pittsburgh International Airport (PIT) to Long Beach Airport (LGB)plane plane PIT - LGB
    12h 22m
    $213–876

  9. Train to Cleveland-Hopkins International Airport, fly to Los Angeles International Airport, train

    1. Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain train
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Los Angeles International Airport (LAX)plane plane CLE - LAX
    3. Take the train from Los Angeles to Santa Anatrain train
    12h 47m
    $255–482

  10. Bus, train

    1. Take the bus from Pittsburgh Intermodal Station to Chicagobus bus FlixBus N2640
    2. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train Southwest Chief
    2d 9h
    $1,296–2,036

Pittsburgh to Santa Ana by train (Amtrak)

Calendar7Weekly Trains
Duration2d 6hAverage Duration
Ticket$1,469Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Pittsburgh to Santa Ana.ExpandLaunch map view
  • Distance: 2,139.5 mi
  • Duration: 10h 9m

What companies run services between Pittsburgh, PA, USA and Santa Ana, CA, USA?

Southwest Airlines, Delta, and two other airlines fly from Pittsburgh International Airport (PIT) to John Wayne Airport Orange County (SNA) every 4 hours. Alternatively, you can take a train from Pittsburgh Amtrak Station to Santa Ana via Chicago Union Station and Fullerton Amtrak Station in around 2d 6h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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