There are 9 ways to get from Pittsburgh to Muscatine by train, bus, bus (Greyhound, Flixbus), car, plane, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Pittsburgh Amtrak Station to Chicago Union StationFloridian
- Take the bus from Chicago, IL to Muscatine, IAChicago
15h 49m$110–304Fly to Quad City International Airport, bus
cheapest- Fly from Pittsburgh International Airport (PIT) to Quad City International Airport (MLI)PIT - MLI
- Take the bus from Moline, IL to Muscatine, IA
9h 44m$94–438Bus
- Take the bus from Pittsburgh Intermodal Station to Chicago Bus StationGreyhound US0164
- Take the bus from Chicago, IL to Muscatine, IAChicago
16h 14m$105–270Drive 635.7 mi
- Drive from Pittsburgh to Muscatine635.7 mi
10h 32m$116–168Bus via Auburn Gresham
- Take the bus from Pittsburgh Intermodal Station to ChicagoFlixBus N2640
- Take the bus from Chicago, IL to Muscatine, IAChicago
17h 53m$115–263Fly to Chicago O'Hare International Airport, bus
- Fly from Pittsburgh International Airport (PIT) to Chicago O'Hare International Airport (ORD)PIT - ORD
- Take the bus from Chicago, IL to Muscatine, IA
10h 41m$135–410Fly to The Eastern Iowa Airport, bus
- Fly from Pittsburgh International Airport (PIT) to The Eastern Iowa Airport (CID)PIT - CID
- Take the bus from Cedar Rapids Airport to Davenport
- Take the bus from Davenport to Muscatine
11h 24m$125–504Fly to Chicago Midway International Airport, train, bus
- Fly from Pittsburgh International Airport (PIT) to Chicago Midway International Airport (MDW)PIT - MDW
- Take the train from Chicago Union Station to Naperville
- Take the bus from Naperville, IL to Muscatine, IA
10h 50m$110–484Fly to Lambert–St. Louis International Airport, bus
- Fly from Pittsburgh International Airport (PIT) to Lambert–St. Louis International Airport (STL)PIT - STL
- Take the bus from Lambert-St. Louis International Airport to Burlington
- Take the bus from Burlington to Muscatine
12h 4m$189–795
Pittsburgh to Muscatine by train, foot, and bus
Questions & Answers
The cheapest way to get from Pittsburgh to Muscatine is to drive which costs $110 - $170 and takes 10h 32m.
The fastest way to get from Pittsburgh to Muscatine is to fly and bus which takes 9h 44m and costs $90 - $440.
No, there is no direct bus from Pittsburgh station to Muscatine. However, there are services departing from Pittsburgh Intermodal Station and arriving at City Hall via Chicago, IL and Mall. The journey, including transfers, takes approximately 16h 14m.
The distance between Pittsburgh and Muscatine is 686 miles. The road distance is 639.4 miles.
The best way to get from Pittsburgh to Muscatine without a car is to train and bus which takes 15h 49m and costs $110 - $310.
It takes approximately 15h 49m to get from Pittsburgh to Muscatine, including transfers.
Pittsburgh to Muscatine bus services, operated by Greyhound USA, depart from Pittsburgh Intermodal Station.
Pittsburgh to Muscatine bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Muscatine is 1h behind Pittsburgh. It is currently 2:14 PM in Pittsburgh and 1:14 PM in Muscatine.
Yes, the driving distance between Pittsburgh to Muscatine is 639 miles. It takes approximately 10h 32m to drive from Pittsburgh to Muscatine.
What companies run services between Pittsburgh, PA, USA and Muscatine, IA, USA?
You can take a bus from Pittsburgh Intermodal Station to City Hall via Chicago, IL and Mall in around 16h 14m.
- Website
- aa.com
Flights from Pittsburgh International Airport to Quad City International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 6h 16m
- When
- Every day
- Estimated price
- $65–400
Flights from Pittsburgh International Airport to Quad City International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 39m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $140–650
Flights from Pittsburgh International Airport to Quad City International Airport via Charlotte
- Ave. Duration
- 7h 44m
- When
- Every day
- Estimated price
- $100–500
Flights from Pittsburgh International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 59m
- When
- Every day
- Estimated price
- $45–290
Flights from Pittsburgh International Airport to The Eastern Iowa Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 44m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–410
Flights from Pittsburgh International Airport to The Eastern Iowa Airport via Reagan Washington
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $95–490
Flights from Pittsburgh International Airport to The Eastern Iowa Airport via Charlotte
- Ave. Duration
- 8h 46m
- When
- Every day
- Estimated price
- $100–550
Flights from Pittsburgh International Airport to Lambert–St. Louis International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $120–700
- Website
- southwest.com
Flights from Pittsburgh International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $60–390
Flights from Pittsburgh International Airport to Chicago Midway International Airport via Lambert–St. Louis International Airport
- Ave. Duration
- 4h
- When
- Saturday
- Estimated price
- $90–470
Flights from Pittsburgh International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $110–650
Flights from Pittsburgh International Airport to Lambert–St. Louis International Airport via Chicago Midway International Airport
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $120–650
Flights from Pittsburgh International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 4h
- When
- Wednesday and Thursday
- Estimated price
- $120–700
- Website
- united.com
Flights from Pittsburgh International Airport to Quad City International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $65–400
Flights from Pittsburgh International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 57m
- When
- Every day
- Estimated price
- $45–290
Flights from Pittsburgh International Airport to The Eastern Iowa Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $70–410
- Website
- delta.com
Flights from Pittsburgh International Airport to Quad City International Airport via Atlanta
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $100–550
Flights from Pittsburgh International Airport to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 3h 36m
- When
- Every day
- Estimated price
- $45–300
Flights from Pittsburgh International Airport to The Eastern Iowa Airport via Minneapolis
- Ave. Duration
- 6h 21m
- When
- Every day
- Estimated price
- $90–480
Flights from Pittsburgh International Airport to The Eastern Iowa Airport via Atlanta
- Ave. Duration
- 5h 51m
- When
- Monday, Tuesday, and Friday
- Estimated price
- $110–550
Flights from Pittsburgh International Airport to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 4h 19m
- When
- Monday, Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $110–650
- Website
- allegiantair.com
Flights from Pittsburgh International Airport to Quad City International Airport via St. Petersburg
- Ave. Duration
- 8h 46m
- When
- Tuesday
- Estimated price
- $150–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Pittsburgh Amtrak Station to Chicago Union Station
- Ave. Duration
- 9h 46m
- Frequency
- Once daily
- Estimated price
- $60–200
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 312-322-6777
- Website
- metra.com
Train from Chicago Union Station to Naperville
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- $3–6
- Website
- https://metra.com
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from Chicago, IL to Muscatine, IA
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $45–104
- Website
- https://burlingtontrailways.com
- Saver Fares
- $45–65
- Flexible Fares
- $60–90
- Saver Fare
- $76
- Flex Fare
- $104
Bus from Moline, IL to Muscatine, IA
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $23–45
- Website
- https://burlingtontrailways.com
- Saver Fares
- $23–35
- Flexible Fares
- $30–45
Bus from Cedar Rapids Airport to Davenport
- Ave. Duration
- 1h 50m
- Frequency
- Twice daily
- Estimated price
- $29–55
- Website
- https://burlingtontrailways.com
- Saver Fares
- $29–45
- Flexible Fares
- $35–55
Bus from Davenport to Muscatine
- Ave. Duration
- 30 min
- Frequency
- 3 times a day
- Estimated price
- $22–45
- Website
- https://burlingtontrailways.com
- Saver Fares
- $22–35
- Flexible Fares
- $29–45
Bus from Naperville, IL to Muscatine, IA
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $40–91
- Website
- https://burlingtontrailways.com
- Saver Fares
- $40–60
- Flexible Fares
- $55–85
- Saver Fare
- $66
- Flex Fare
- $91
Bus from Lambert-St. Louis International Airport to Burlington
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- $45–120
- Website
- https://burlingtontrailways.com
- Saver Fares
- $45–70
- Flexible Fares
- $65–95
- Saver Fare
- $86
- Flex Fare
- $120
Bus from Burlington to Muscatine
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $25–50
- Website
- https://burlingtontrailways.com
- Saver Fares
- $25–40
- Flexible Fares
- $30–50
- Saver Fare
- $26–35
- Flex Fare
- $30–45
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Pittsburgh Intermodal Station to Chicago Bus Station
- Ave. Duration
- 10h 20m
- Frequency
- 4 times a day
- Estimated price
- $55–160
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Pittsburgh Intermodal Station to Chicago Bus Station
- Ave. Duration
- 11h 25m
- Frequency
- Twice daily
- Estimated price
- $60–140
- Schedules at
- flixbus.com
Bus from Pittsburgh Intermodal Station to Chicago
- Ave. Duration
- 10h 55m
- Frequency
- Twice daily
- Estimated price
- $60–110
- Schedules at
- flixbus.com
- Adult
- $60–110
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