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How to get fromPittsburgh to Durhamby bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car or train

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There are 5 ways to get from Pittsburgh to Durham by bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Pittsburgh International Airport, fly

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Raleigh-Durham International Airport (RDU)plane plane PIT - RDU
    5h 11m

  2. Bus

    cheapest
    1. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus bus Greyhound US0164 / ...
    2. Take the bus from Washington Union Station to Durhambus bus FlixBus N2471 / ...
    11h 10m
    $61–169

  3. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Carytrain train Floridian
    16h 28m
    $172–367

  4. Drive 407 mi

    1. Drive from Pittsburgh to Durhamcar car 407 mi
    9h 17m
    $75–108

  5. Train to Cleveland-Hopkins International Airport, fly

    1. Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain train
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Raleigh-Durham International Airport (RDU)plane plane CLE - RDU
    7h 55m
    $232–640

Pittsburgh to Durham by bus

Calendar32Weekly Buses
Duration11h 10mAverage Duration
Ticket$61Cheapest Price
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Questions & Answers

What companies run services between Pittsburgh, PA, USA and Durham, NC, USA?

You can take a bus from Pittsburgh Intermodal Station to Durham via Washington Union Station in around 11h 10m. Alternatively, Amtrak operates a train from Pittsburgh Amtrak Station to Cary once daily. Tickets cost $170–370 and the journey takes 14h 41m.

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