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How to get fromPittsburgh to Durhamby bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car or train

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There are 5 ways to get from Pittsburgh to Durham by bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Pittsburgh International Airport, fly, bus, line 700 bus

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Raleigh-Durham International Airport (RDU)plane plane PIT - RDU
    3. Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus bus
    4. Take the bus from Regional Transit Center to Pettigrew St at Parking Deckbus bus
    5h 9m

  2. Bus

    cheapest
    1. Take the bus from Pittsburgh Intermodal Station to Washington Union Stationbus bus Greyhound US0164 / ...
    2. Take the bus from Washington Union Station to Durhambus bus FlixBus N2471 / ...
    11h 10m
    $62–163

  3. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Carytrain train Floridian
    16h 28m
    $169–369

  4. Drive 407 mi

    1. Drive from Pittsburgh to Durhamcar car 407 mi
    9h 19m
    $75–108

  5. Train to Cleveland-Hopkins International Airport, fly

    1. Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain train
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Raleigh-Durham International Airport (RDU)plane plane CLE - RDU
    7h 57m
    $312–591

Pittsburgh to Durham by bus

Calendar34Weekly Buses
Duration11h 10mAverage Duration
Ticket$62Cheapest Price
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Questions & Answers

What companies run services between Pittsburgh, PA, USA and Durham, NC, USA?

You can take a bus from Pittsburgh Intermodal Station to Durham via Washington Union Station in around 11h 10m. Alternatively, Amtrak operates a train from Pittsburgh Amtrak Station to Cary once daily. Tickets cost $160–370 and the journey takes 14h 41m.

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