There are 7 ways to get from Pisa to Mendrisio by train (Trenitalia), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Florence
best- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Milano Centraletrain Fr
- Take the train from Milano Centrale to Mendrisiotrain
5h 10mCHF 58–160Bus, train
cheapest- Take the bus from Pisa to Milanbus N1508 / ...
- Take the train from Malpensa Aeroporto T2 to Mendrisiotrain S50
7h 34mCHF 34–115Bus
- Take the bus from Pisa Airport to Florence Villa Constanza Bus Stationbus BlaBlaCar Bus
- Take the bus from Florence Villa Constanza Bus Station to Comobus
6h 12mDrive 337.8 km
- Drive from Pisa to Mendrisiocar 337.8 km
3h 36mCHF 56–80Fly Pisa International Airport to Milan Linate Airport, train
- Fly from Pisa International Airport (PSA) to Milan Linate Airport (LIN)plane PSA - LIN
- Take the train from Monza to Mendrisiotrain
6h 9mCHF 91–211Train
- Take the train from Pisa Centrale to Milano Centraletrain Fb
- Take the train from Milano Centrale to Mendrisiotrain Re80
5h 18mCHF 49–141Train to Florence Peretola Airport, fly to Milano Malpensa Airport, train
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Milano Malpensa Airport (MXP)plane FLR - MXP
- Take the train from Malpensa Aeroporto T1 to Mendrisiotrain
7h 19mCHF 100–257
Pisa to Mendrisio by train
Questions & Answers
The cheapest way to get from Pisa to Mendrisio is to bus and train which costs SFr 30 - SFr 120 and takes 7h 34m.
The fastest way to get from Pisa to Mendrisio is to drive which takes 3h 36m and costs SFr 55 - SFr 80.
No, there is no direct bus from Pisa to Mendrisio. However, there are services departing from Pisa Airport and arriving at Mendrisio, Autosilo via Florence Villa Constanza Bus Station, Como - Chiesa di San Zenone and Chiasso, Stazione. The journey, including transfers, takes approximately 6h 12m.
No, there is no direct train from Pisa to Mendrisio. However, there are services departing from Pisa Centrale and arriving at Mendrisio via Firenze S.M.N. and Milano Centrale. The journey, including transfers, takes approximately 5h 10m.
The distance between Pisa and Mendrisio is 441 km. The road distance is 337.8 km.
The best way to get from Pisa to Mendrisio without a car is to train via Florence which takes 5h 10m and costs SFr 55 - SFr 160.
It takes approximately 5h 10m to get from Pisa to Mendrisio, including transfers.
Pisa to Mendrisio bus services, operated by BlaBlaCar Bus, depart from Pisa Airport station.
Pisa to Mendrisio train services, operated by Trenitalia, depart from Pisa Centrale station.
The best way to get from Pisa to Mendrisio is to train via Florence which takes 5h 10m and costs SFr 55 - SFr 160. Alternatively, you can bus, which costs and takes 6h 12m.
What companies run services between Pisa, Italy and Mendrisio, Switzerland?
You can take a train from Pisa Centrale to Mendrisio via Firenze S.M.N. and Milano Centrale in around 5h 10m. Alternatively, you can take a bus from Pisa Airport to Mendrisio, Autosilo via Florence Villa Constanza Bus Station, Como, Como - Chiesa di San Zenone, and Chiasso, Stazione in around 6h 12m.
- Website
- ita-airways.com
Flights from Pisa International Airport to Milan Linate Airport via Alghero
- Ave. Duration
- 3h 55m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- CHF 85–200
Flights from Pisa International Airport to Milan Linate Airport via Brindisi
- Ave. Duration
- 4h 5m
- When
- Monday, Tuesday, Saturday, and Sunday
- Estimated price
- CHF 85–200
Flights from Florence Peretola Airport to Milano Malpensa Airport via Zurich
- Ave. Duration
- 3h 31m
- When
- Every day
- Estimated price
- CHF 80–270
Flights from Florence Peretola Airport to Milano Malpensa Airport via Munich
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- CHF 130–480
- Website
- flexflight.dk
Flights from Pisa International Airport to Milan Linate Airport via Cagliari
- Ave. Duration
- 3h 55m
- When
- Thursday and Sunday
- Estimated price
- CHF 95–650
Flights from Pisa International Airport to Milan Linate Airport via Elba Island
- Ave. Duration
- 5h 25m
- When
- Friday
- Estimated price
- CHF 35–440
- Website
- lufthansa.com
Flights from Pisa International Airport to Milan Linate Airport via Frankfurt
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- CHF 160–600
Flights from Florence Peretola Airport to Milano Malpensa Airport via Munich
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- CHF 130–480
- Website
- swiss.com
Flights from Florence Peretola Airport to Milano Malpensa Airport via Zurich
- Ave. Duration
- 3h 31m
- When
- Every day
- Estimated price
- CHF 80–270
- Website
- aeroitalia.com
Flights from Pisa International Airport to Milan Linate Airport via Cagliari
- Ave. Duration
- 3h 55m
- When
- Thursday and Sunday
- Estimated price
- CHF 95–650
- Website
- polarair.ru
Flights from Pisa International Airport to Milan Linate Airport via Elba Island
- Ave. Duration
- 5h 25m
- When
- Friday
- Estimated price
- CHF 35–440
- Website
- airdolomiti.it
Flights from Florence Peretola Airport to Milano Malpensa Airport via Munich
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- CHF 130–480
- Website
- easyjet.com
Flights from Florence Peretola Airport to Milano Malpensa Airport via Olbia
- Ave. Duration
- 3h 20m
- When
- Saturday
- Estimated price
- CHF 45–220
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 15 minutes
- Estimated price
- CHF 9–15
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Milano Centrale
- Ave. Duration
- 4h 25m
- Frequency
- Twice daily
- Estimated price
- CHF 35–60
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 15 minutes
- Estimated price
- CHF 9–15
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- CHF 40–85
- Schedules at
- trenitalia.com
Train from Pisa Centrale to Milano Centrale
- Ave. Duration
- 3h 44m
- Frequency
- Twice daily
- Estimated price
- CHF 40–85
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 2h 37m
- Frequency
- 4 times a day
- Estimated price
- CHF 35–75
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 3h 54m
- Frequency
- 3 times a day
- Estimated price
- CHF 30–65
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Milano Centrale
- Ave. Duration
- 6h
- Frequency
- Hourly
- Estimated price
- CHF 30–65
- Website
- https://www.trenitalia.com/en.html
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Milano Centrale to Mendrisio
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- CHF 19–60
- Website
- https://www.sbb.ch/en
Train from Milano Centrale to Mendrisio
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- CHF 19–60
- Website
- https://www.sbb.ch/en
Train from Malpensa Aeroporto T2 to Mendrisio
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- CHF 20–65
- Website
- https://www.sbb.ch/en
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 19–60
- Website
- https://www.sbb.ch/en
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Monza to Mendrisio
- Ave. Duration
- 48 min
- Frequency
- Hourly
- Estimated price
- CHF 2–4
- Website
- https://www.trenord.it/en/
Train from Malpensa Aeroporto T2 to Mendrisio
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- CHF 4–6
- Website
- https://www.trenord.it/en/
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 4–6
- Website
- https://www.trenord.it/en/
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Pisa Airport to Florence Villa Constanza Bus Station
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- CHF 6–12
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- onebus.it
Bus from Florence Villa Constanza Bus Station to Como
- Ave. Duration
- 3h 7m
- Frequency
- Once a week
- Website
- https://onebus.it/
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Pisa to Milan
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- CHF 30–50
- Website
- https://www.flixbus.co.uk
Want to know more about travelling around Switzerland
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More Questions & Answers
Pisa to Mendrisio bus services, operated by BlaBlaCar Bus, arrive at Florence Villa Constanza Bus Station.
Pisa to Mendrisio train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Pisa to Mendrisio is 338 km. It takes approximately 3h 36m to drive from Pisa to Mendrisio.
There are 5903+ hotels available in Mendrisio.

































