There are 8 ways to get from Pisa to Mendrisio by train (Trenitalia), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Florence
best- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Milano Centraletrain Fr
- Take the train from Milano Centrale to Mendrisiotrain
5h 35mCHF 57–133Train #2
cheapest- Take the train from Pisa Centrale to La Spezia Centraletrain Re
- Take the train from La Spezia Centrale to Como Camerlatatrain Re 13
7h 32mCHF 21–81Bus
- Take the bus from Pisa to Milanbus N1508 / ...
- Take the bus from Milan to Mendrisiobus FlixBus 470
7h 59mCHF 24–41Drive 337.8 km
- Drive from Pisa to Mendrisiocar 337.8 km
3h 36mCHF 53–77Fly Pisa International Airport to Milano Malpensa Airport, train
- Fly from Pisa International Airport (PSA) to Milano Malpensa Airport (MXP)plane PSA - MXP
- Take the train from Malpensa Aeroporto T1 to Mendrisiotrain
5h 12mCHF 46–168Train (Trenitalia)
- Take the train from Pisa Centrale to Chiassotrain Ec
7h 16mCHF 71–116Fly Pisa International Airport to Milan Linate Airport, train
- Fly from Pisa International Airport (PSA) to Milan Linate Airport (LIN)plane PSA - LIN
- Take the train from Monza to Mendrisiotrain
5h 40mCHF 95–236Train to Florence Peretola Airport, fly to Milano Malpensa Airport, train
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Milano Malpensa Airport (MXP)plane FLR - MXP
- Take the train from Malpensa Aeroporto T1 to Mendrisiotrain
7h 31mCHF 72–196
Pisa to Mendrisio by train
Questions & Answers
The cheapest way to get from Pisa to Mendrisio is to bus which costs SFr 24 - SFr 45 and takes 7h 59m.
The fastest way to get from Pisa to Mendrisio is to drive which takes 3h 36m and costs SFr 50 - SFr 80.
No, there is no direct bus from Pisa to Mendrisio. However, there are services departing from Pisa and arriving at Mendrisio via Milan. The journey, including transfers, takes approximately 7h 59m.
No, there is no direct train from Pisa to Mendrisio. However, there are services departing from Pisa Centrale and arriving at Mendrisio via Firenze S.M.N. and Milano Centrale. The journey, including transfers, takes approximately 5h 35m.
The distance between Pisa and Mendrisio is 441 km. The road distance is 337.8 km.
The best way to get from Pisa to Mendrisio without a car is to train via Florence which takes 5h 35m and costs SFr 55 - SFr 140.
It takes approximately 5h 35m to get from Pisa to Mendrisio, including transfers.
Pisa to Mendrisio bus services, operated by FlixBus, depart from Pisa station.
Pisa to Mendrisio train services, operated by Trenitalia, depart from Pisa Centrale station.
The best way to get from Pisa to Mendrisio is to train via Florence which takes 5h 35m and costs SFr 55 - SFr 140. Alternatively, you can bus, which costs SFr 24 - SFr 45 and takes 7h 59m.
What companies run services between Pisa, Italy and Mendrisio, Switzerland?
You can take a train from Pisa Centrale to Mendrisio via Firenze S.M.N. and Milano Centrale in around 5h 35m. Alternatively, you can take a bus from Pisa to Mendrisio via Milan in around 7h 59m.
- Website
- ita-airways.com
Flights from Pisa International Airport to Milan Linate Airport via Bari
- Ave. Duration
- 3h 45m
- When
- Monday, Thursday, and Friday
- Estimated price
- CHF 95–300
Flights from Pisa International Airport to Milan Linate Airport via Brindisi
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- CHF 95–300
Flights from Pisa International Airport to Milan Linate Airport via Palermo
- Ave. Duration
- 4h 15m
- When
- Monday, Thursday, and Friday
- Estimated price
- CHF 95–300
Flights from Florence Peretola Airport to Milano Malpensa Airport via Zurich
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- CHF 55–140
Flights from Florence Peretola Airport to Milano Malpensa Airport via Munich
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- CHF 95–440
- Website
- lufthansa.com
Flights from Pisa International Airport to Milano Malpensa Airport via Frankfurt
- Ave. Duration
- 7h 25m
- When
- Saturday
- Estimated price
- CHF 95–500
Flights from Pisa International Airport to Milan Linate Airport via Frankfurt
- Ave. Duration
- 6h 30m
- When
- Saturday
- Estimated price
- CHF 110–600
Flights from Florence Peretola Airport to Milano Malpensa Airport via Munich
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- CHF 95–440
- Website
- ryanair.com
Flights from Pisa International Airport to Milano Malpensa Airport via Palermo
- Ave. Duration
- 5h 31m
- When
- Monday, Friday, and Sunday
- Estimated price
- CHF 40–170
Flights from Pisa International Airport to Milano Malpensa Airport via Bari
- Ave. Duration
- 5h 10m
- When
- Sunday
- Estimated price
- CHF 40–170
- Website
- airdolomiti.it
Flights from Pisa International Airport to Milano Malpensa Airport via Frankfurt
- Ave. Duration
- 7h 25m
- When
- Saturday
- Estimated price
- CHF 95–500
Flights from Pisa International Airport to Milan Linate Airport via Frankfurt
- Ave. Duration
- 6h 30m
- When
- Saturday
- Estimated price
- CHF 110–600
Flights from Florence Peretola Airport to Milano Malpensa Airport via Munich
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- CHF 95–440
- Website
- easyjet.com
Flights from Pisa International Airport to Milano Malpensa Airport via Cagliari
- Ave. Duration
- 3h 45m
- When
- Sunday
- Estimated price
- CHF 40–180
Flights from Pisa International Airport to Milano Malpensa Airport via Palermo
- Ave. Duration
- 6h 50m
- When
- Saturday
- Estimated price
- CHF 45–190
Flights from Pisa International Airport to Milan Linate Airport via Paris Orly
- Ave. Duration
- 4h 5m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- CHF 95–210
- Website
- flexflight.dk
Flights from Pisa International Airport to Milan Linate Airport via Cagliari
- Ave. Duration
- 3h 57m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- CHF 80–280
Flights from Florence Peretola Airport to Milano Malpensa Airport via Rome
- Ave. Duration
- 3h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- CHF 120–170
- Website
- aeroitalia.com
Flights from Pisa International Airport to Milan Linate Airport via Cagliari
- Ave. Duration
- 3h 57m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- CHF 80–280
Flights from Florence Peretola Airport to Milano Malpensa Airport via Rome
- Ave. Duration
- 3h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- CHF 120–170
- Website
- swiss.com
Flights from Florence Peretola Airport to Milano Malpensa Airport via Zurich
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- CHF 55–140
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 25m
- Frequency
- Every 30 minutes
- Estimated price
- CHF 5–8
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to La Spezia Centrale
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- CHF 5–8
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- CHF 35–80
- Schedules at
- trenitalia.com
Train from Pisa Centrale to La Spezia Centrale
- Ave. Duration
- 51 min
- Frequency
- Every 4 hours
- Estimated price
- CHF 9–19
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 3h 54m
- Frequency
- Once daily
- Estimated price
- CHF 27–65
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to La Spezia Centrale
- Ave. Duration
- 58 min
- Frequency
- Every 4 hours
- Estimated price
- CHF 6–15
- Website
- https://www.trenitalia.com/en.html
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Milano Centrale to Mendrisio
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- CHF 24–45
- Website
- https://www.sbb.ch/en
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 24–45
- Website
- https://www.sbb.ch/en
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 4–6
- Website
- https://www.trenord.it/en/
Train from La Spezia Centrale to Como Camerlata
- Ave. Duration
- 4h 38m
- Frequency
- Twice a week
- Estimated price
- CHF 15–20
- Website
- https://www.trenord.it/en/
Train from Monza to Mendrisio
- Ave. Duration
- 48 min
- Frequency
- Hourly
- Estimated price
- CHF 2–3
- Website
- https://www.trenord.it/en/
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Pisa Centrale to Chiasso
- Ave. Duration
- 6h 36m
- Frequency
- Twice a week
- Estimated price
- CHF 65–120
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- CHF 80–120
- 2nd Class
- CHF 65–90
Train from Pisa Centrale to La Spezia Centrale
- Ave. Duration
- 1h 8m
- Frequency
- Twice a week
- Estimated price
- CHF 21–60
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- CHF 40–60
- 2nd Class
- CHF 21–29
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Pisa to Milan
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- CHF 21–40
- Website
- https://www.flixbus.co.uk
Bus from Milan to Mendrisio
- Ave. Duration
- 59 min
- Frequency
- Twice daily
- Estimated price
- CHF 3–6
- Website
- https://www.flixbus.co.uk
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More Questions & Answers
Pisa to Mendrisio bus services, operated by FlixBus, arrive at Milan station.
Pisa to Mendrisio train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Pisa to Mendrisio is 338 km. It takes approximately 3h 36m to drive from Pisa to Mendrisio.
Book your Pisa to Mendrisio bus tickets online with FlixBus.
There are 5091+ hotels available in Mendrisio.





























