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How to get fromPisa to Mendrisioby train (Trenitalia), bus, car, plane, or train

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There are 7 ways to get from Pisa to Mendrisio by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Florence

    best
    1. Take the train from Pisa Centrale to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Mendrisiotrain train
    5h 27m
    CHF 58–154

  2. Bus, train

    cheapest
    1. Take the bus from Pisa to Milanbus bus N1508
    2. Take the train from Monza to Mendrisiotrain train Re80 / ...
    8h 35m
    CHF 35–58

  3. Bus

    1. Take the bus from Pisa to Florencebus bus FlixBus 507
    2. Take the bus from Florence Villa Constanza Bus Station to Comobus bus
    6h 47m
    CHF 64–96

  4. Drive  337.8 km

    1. Drive from Pisa to Mendrisiocar car 337.8 km
    3h 36m
    CHF 57–82

  5. Fly Pisa International Airport to Milan Linate Airport, train

    1. Fly from Pisa International Airport (PSA) to Milan Linate Airport (LIN)plane plane PSA - LIN
    2. Take the train from Monza to Mendrisiotrain train
    5h 49m
    CHF 97–262

  6. Train

    1. Take the train from Pisa Centrale to Chiassotrain train Ec
    7h 16m
    CHF 74–342

  7. Bus to Florence Peretola Airport, fly to Milano Malpensa Airport, train

    1. Take the bus from Pisa International Airport to Florence Airportbus bus
    2. Fly from Florence Peretola Airport (FLR) to Milano Malpensa Airport (MXP)plane plane FLR - MXP
    3. Take the train from Malpensa Aeroporto T1 to Mendrisiotrain train
    6h 44m
    CHF 110–299

Pisa to Mendrisio by train

Calendar137Weekly Trains
Duration5h 27mAverage Duration
TicketCHF 58Cheapest Price
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Questions & Answers

Map of how to get from Pisa to Mendrisio.ExpandLaunch map view
  • Distance: 440.6 km
  • Duration: 5h 27m

What companies run services between Pisa, Italy and Mendrisio, Switzerland?

You can take a train from Pisa Centrale to Mendrisio via Firenze S.M.N. and Milano Centrale in around 5h 27m. Alternatively, you can take a bus from Pisa to Mendrisio, Autosilo via Florence Villa Constanza Bus Station, Como, Como - Chiesa di San Zenone, and Chiasso, Stazione in around 6h 47m.

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