There are 7 ways to get from Pisa to Mendrisio by train, bus, car, plane, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Florence
best- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Florence Santa Maria Novella to Milano Centraletrain
- Take the train from Milano Centrale to Mendrisiotrain
5h 45mCHF 58–132Train #2
cheapest- Take the train from Pisa Centrale to La Spezia Centraletrain Re
- Take the train from La Spezia Centrale to Como Camerlatatrain Re 13
7h 21mCHF 26–84Bus
- Take the bus from Pisa to Milanbus N1508 / ...
- Take the bus from Milan to Mendrisiobus 470
7h 59mCHF 36–58Drive 337.4 km
- Drive from Pisa to Mendrisiocar 337.4 km
3h 36mCHF 55–79Fly Pisa International Airport to Milan Linate Airport, train
- Fly from Pisa International Airport (PSA) to Milan Linate Airport (LIN)plane PSA - LIN
- Take the train from Monza to Mendrisiotrain
5h 41mCHF 92–248Train (Trenitalia)
- Take the train from Pisa Centrale to Chiassotrain Ec
7h 16mCHF 73–120Train to Florence Peretola Airport, fly to Milano Malpensa Airport, train
- Take the train from Pisa Centrale to Firenze S.M.N.train
- Fly from Florence Peretola Airport (FLR) to Milano Malpensa Airport (MXP)plane FLR - MXP
- Take the train from Malpensa Aeroporto T1 to Mendrisiotrain
7h 28mCHF 80–220
Pisa to Mendrisio by train
Questions & Answers
The cheapest way to get from Pisa to Mendrisio is to train which costs SFr 25 - SFr 85 and takes 7h 21m.
The fastest way to get from Pisa to Mendrisio is to drive which takes 3h 36m and costs SFr 50 - SFr 80.
No, there is no direct bus from Pisa to Mendrisio. However, there are services departing from Pisa and arriving at Mendrisio via Milan. The journey, including transfers, takes approximately 7h 59m.
No, there is no direct train from Pisa to Mendrisio. However, there are services departing from Pisa Centrale and arriving at Mendrisio via Florence Santa Maria Novella and Milano Centrale. The journey, including transfers, takes approximately 5h 45m.
The distance between Pisa and Mendrisio is 440 km. The road distance is 337.4 km.
The best way to get from Pisa to Mendrisio without a car is to train via Florence which takes 5h 45m and costs SFr 55 - SFr 140.
It takes approximately 5h 45m to get from Pisa to Mendrisio, including transfers.
Pisa to Mendrisio bus services, operated by FlixBus, depart from Pisa station.
Pisa to Mendrisio train services, operated by Trenitalia S.p.A., depart from Pisa Centrale station.
The best way to get from Pisa to Mendrisio is to train via Florence which takes 5h 45m and costs SFr 55 - SFr 140. Alternatively, you can bus, which costs SFr 35 - SFr 60 and takes 7h 59m.
What companies run services between Pisa, Italy and Mendrisio, Switzerland?
You can take a train from Pisa Centrale to Mendrisio via Florence Santa Maria Novella and Milano Centrale in around 5h 45m. Alternatively, you can take a bus from Pisa to Mendrisio via Milan in around 7h 59m.
- Website
- ita-airways.com
Flights from Pisa International Airport to Milan Linate Airport via Bari
- Ave. Duration
- 3h 45m
- When
- Monday, Thursday, and Friday
- Estimated price
- CHF 90–300
Flights from Pisa International Airport to Milan Linate Airport via Palermo
- Ave. Duration
- 6h
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- CHF 90–300
Flights from Florence Peretola Airport to Milano Malpensa Airport via Zurich
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- CHF 65–190
Flights from Florence Peretola Airport to Milano Malpensa Airport via Munich
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- CHF 100–330
- Website
- lufthansa.com
Flights from Pisa International Airport to Milan Linate Airport via Frankfurt
- Ave. Duration
- 6h 30m
- When
- Saturday
- Estimated price
- CHF 120–380
Flights from Florence Peretola Airport to Milano Malpensa Airport via Munich
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- CHF 100–330
- Website
- airdolomiti.it
Flights from Pisa International Airport to Milan Linate Airport via Frankfurt
- Ave. Duration
- 6h 30m
- When
- Saturday
- Estimated price
- CHF 120–380
Flights from Florence Peretola Airport to Milano Malpensa Airport via Munich
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- CHF 100–330
- Website
- aeroitalia.com
Flights from Pisa International Airport to Milan Linate Airport via Cagliari
- Ave. Duration
- 3h 25m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- CHF 90–600
Flights from Florence Peretola Airport to Milano Malpensa Airport via Rome
- Ave. Duration
- 3h 15m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- CHF 55–200
- Website
- flexflight.dk
Flights from Pisa International Airport to Milan Linate Airport via Cagliari
- Ave. Duration
- 3h 25m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- CHF 90–600
Flights from Florence Peretola Airport to Milano Malpensa Airport via Rome
- Ave. Duration
- 3h 15m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- CHF 55–200
- Website
- swiss.com
Flights from Florence Peretola Airport to Milano Malpensa Airport via Zurich
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- CHF 65–190
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- CHF 8–22
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to La Spezia Centrale
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- CHF 7–19
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- CHF 25–65
- Website
- https://www.italotreno.it/en
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Milano Centrale to Mendrisio
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- CHF 24–45
- Website
- https://www.sbb.ch/en
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 24–45
- Website
- https://www.sbb.ch/en
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Monza to Mendrisio
- Ave. Duration
- 48 min
- Frequency
- Hourly
- Estimated price
- CHF 2–4
- Website
- https://www.trenord.it/en/
Train from La Spezia Centrale to Como Camerlata
- Ave. Duration
- 4h 29m
- Frequency
- Twice a week
- Estimated price
- CHF 16–20
- Website
- https://www.trenord.it/en/
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 4–6
- Website
- https://www.trenord.it/en/
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Pisa Centrale to Chiasso
- Ave. Duration
- 6h 36m
- Frequency
- Twice a week
- Estimated price
- CHF 70–120
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- CHF 80–120
- 2nd Class
- CHF 70–95
Train from Pisa Centrale to La Spezia Centrale
- Ave. Duration
- 1h 8m
- Frequency
- Twice a week
- Estimated price
- CHF 22–65
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- CHF 40–65
- 2nd Class
- CHF 22–29
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to La Spezia Centrale
- Ave. Duration
- 51 min
- Frequency
- Every 4 hours
- Estimated price
- CHF 13–19
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to La Spezia Centrale
- Ave. Duration
- 1h 13m
- Frequency
- Every 4 hours
- Estimated price
- CHF 8–11
- Website
- https://www.trenitalia.com/en.html
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Pisa to Milan
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- CHF 30–50
- Website
- https://www.flixbus.co.uk
Bus from Milan to Mendrisio
- Ave. Duration
- 59 min
- Frequency
- Once daily
- Estimated price
- CHF 6–10
- Website
- https://www.flixbus.co.uk
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More Questions & Answers
Pisa to Mendrisio bus services, operated by FlixBus, arrive at Milan station.
Pisa to Mendrisio train services, operated by Trenitalia S.p.A., arrive at Firenze S.M.N. station.
Yes, the driving distance between Pisa to Mendrisio is 337 km. It takes approximately 3h 36m to drive from Pisa to Mendrisio.
Book your Pisa to Mendrisio bus tickets online with FlixBus.
There are 4857+ hotels available in Mendrisio.



































