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How to get fromPisa to Madridby plane, train (Trenitalia, Renfe, Ouigo), bus, car or train (Trenitalia, TGV, Renfe)

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There are 6 ways to get from Pisa to Madrid by plane, train (Trenitalia, Renfe, Ouigo), bus, car, or train (Trenitalia, TGV, Renfe)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Pisa International Airport (PSA) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane PSA - MAD
    2h 35m
    €65–197
  2. Train via Barcelona

    1. Take the train from Pisa Centrale to Firenze S.M.N.train train Re
    2. Take the train from Florence Santa Maria Novella to Milano Centraletrain train
    3. Take the train from Milano Centrale to Lyon Part Dieutrain train Fr
    4. Take the train from Lyon Part Dieu to Barcelona-Santstrain train
    5. Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain train Ave
    18h 23m
    €164–448
  3. Bus

    1. Take the bus from Pisa to Genoabus bus N1508 / ...
    2. Take the bus from Genoa to Madridbus bus FlixBus N1138
    25h 15m
    €74–206
  4. Drive 1,572 km

    1. Drive from Pisa to Madridcar car 1,572 km
    15h 40m
    €246–354
  5. Train

    1. Take the train from Pisa Centrale to Ventimigliatrain train Ic
    2. Take the train from Nice Ville to Aix En Provence Tgvtrain train Tgv
    3. Take the train from Aix En Provence Tgv to Madrid-Puerta de Atocha-Almudena Grandestrain train
    18h 28m
    €157–263
  6. Bus via Turin

    1. Take the bus from PISA - Via Pietrasantina Parcheggio to Turinbus bus Reggio Calabria
    2. Take the bus from Turin Corso Vittorio Emanuele II to Madrid Mendez Alvaro Estacion Surbus bus Union Ivkoni - Unibus 3415 / ...
    31h 5m
    €87–119

Pisa to Madrid by train

Calendar7Weekly Trains
Duration18h 23mAverage Duration
Ticket€164Cheapest Price
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Questions & Answers

What companies run services between Pisa, Italy and Madrid, Spain?

Ryanair flies from Pisa International Airport (PSA) to Adolfo Suárez Madrid–Barajas Airport (MAD) 5 times a week. Alternatively, you can take a train from Pisa Centrale to Madrid-Puerta de Atocha-Almudena Grandes via Florence Santa Maria Novella, Milano Centrale, Lyon Part Dieu, and Barcelona-Sants in around 18h 23m.

Airlines
Train operators
Bus operators

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