There are 6 ways to get from Pisa to Madrid by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  3h 6m

  1. Fly from Pisa (PSA) to Madrid (MAD) PSA - MAD

50€ - 190€

5 alternative options

Train  •  17h 6m

  1. Take the train from Pisa Centrale to Genova P.Za Principe Fb / ...
  2. Take the train from Genova P.Za Principe to Marseille St Charles Ec
  3. Take the train from Marseille St Charles to Madrid-Puerta De Atocha Ave

120€ - 220€

Train via Antibes  •  18h 25m

  1. Take the train from Pisa Centrale to Ventimiglia Ic
  2. Take the train from Ventimiglia to Antibes Ter / ...
  3. Take the train from Antibes to Marseille St Charles Tgv / ...
  4. Take the train from Marseille St Charles to Madrid-Puerta De Atocha Ave

127€ - 233€

Bus via Genoa  •  27h 46m

  1. Take the bus from Pisa, Pisa to Genoa, Genoa 516 / ...
  2. Take the bus from Genoa - Via Fanti d'Italia to Nice - Airport
  3. Take the bus from Niza to Madrid

121€ - 187€

Bus  •  29h 16m

  1. Take the bus from Pisa to Nice - Ferber Reggio Calabria
  2. Take the bus from Nice Aéroport to Madrid Est Sur 252

78€ - 107€

Drive  •  15h 32m

  1. Drive from Pisa to Madrid 1622.9 km

220€ - 330€

Coronavirus (COVID-19) in Spain

There is widespread community transmission globally.
Some travel restrictions are being lifted in Spain. For the latest travel status, please check the official page for Spain.

For travel planning advice, please refer to our Rome2rio Coronavirus information page .
For the latest travel status, we recommend checking the official page for Spain.

Coronavirus (COVID-19) Travel Advice

Some border closures are in place for Spain due to Coronavirus (COVID-19). Most travel to this country is restricted.

Source Type: Government | Last updated: 5/16/2020

Some domestic travel restrictions began to ease in Spain from 5/9/2020.

Source Type: Government | Last updated: 5/11/2020

International flights leaving Italy are suspended as part of the response to Coronavirus (COVID-19). Restrictions may also be in place for other modes of transport.

Source Type: Government | Last updated: 4/18/2020

Data sourced from: CDC, ACAPS, OXFORD

Questions & Answers

The cheapest way to get from Pisa to Madrid is to fly which costs 50€ - 190€ and takes 3h 6m.

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The quickest way to get from Pisa to Madrid is to fly which costs 50€ - 190€ and takes 3h 6m.

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No, there is no direct bus from Pisa to Madrid. However, there are services departing from Pisa, Pisa and arriving at Madrid via Genoa - Via Fanti d'Italia and Niza. The journey, including transfers, takes approximately 27h 46m.

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No, there is no direct train from Pisa to Madrid. However, there are services departing from Pisa Centrale and arriving at Madrid-Puerta De Atocha via Genova P.Za Principe and Marseille St Charles. The journey, including transfers, takes approximately 17h 6m.

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The distance between Pisa and Madrid is 1219 km. The road distance is 1622.9 km.

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The best way to get from Pisa to Madrid without a car is to train which takes 17h 6m and costs 120€ - 220€.

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It takes approximately 3h 6m to get from Pisa to Madrid, including transfers.

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Pisa to Madrid bus services, operated by FlixBus, depart from Pisa, Pisa station.

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Pisa to Madrid train services, operated by Trenitalia Frecce, depart from Pisa Centrale station.

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The best way to get from Pisa to Madrid is to fly which takes 3h 6m and costs 50€ - 190€. Alternatively, you can train, which costs 120€ - 220€ and takes 17h 6m, you could also bus via Genoa, which costs 120€ - 190€ and takes 27h 46m.

Mode details

Map of how to get from Pisa to Madrid.
Launch map view
  • Distance: 1218.9 km
  • Duration: 3h 6m

What companies run services between Pisa, Italy and Madrid, Spain?

Ryanair, Alitalia and four other airlines fly from Pisa to Madrid every 4 hours. Alternatively, you can take a train from Pisa to Madrid via Genova P.Za Principe and Marseille St Charles in around 17h 6m.

Airlines
Ryanair
Website
ryanair.com
Flights from Pisa to Madrid
Ave. Duration
2h 20m
When
Every day
Estimated price
50€ - 220€
Flights from Pisa to Madrid via Palermo
Ave. Duration
4h 50m
When
Monday, Tuesday, Thursday, Saturday and Sunday
Estimated price
50€ - 220€
Flights from Pisa to Madrid via Charleroi
Ave. Duration
5h 25m
When
Every day
Estimated price
50€ - 220€
Flights from Pisa to Madrid via Beauvais
Ave. Duration
5h 30m
When
Monday, Thursday, Friday and Saturday
Estimated price
50€ - 220€
Alitalia
Website
alitalia.com
Flights from Pisa to Madrid via Rome
Ave. Duration
5h 18m
When
Every day
Estimated price
120€ - 300€
Vueling Airlines
Website
vueling.com
Flights from Pisa to Madrid via Barcelona
Ave. Duration
5h 15m
When
Tuesday, Thursday, Friday and Sunday
Estimated price
150€ - 300€
Lufthansa
Website
lufthansa.com
Flights from Pisa to Madrid via Munich
Ave. Duration
4h 55m
When
Every day
Estimated price
160€ - 350€
Air Europa
Website
aireuropa.com
Flights from Pisa to Madrid via Rome
Ave. Duration
5h 35m
When
Every day
Estimated price
130€ - 360€
Train operators
Trenitalia Frecce

Trenitalia’s high-speed Frecce trains run on specialised tracks and have a greater level of service and comfort than InterCity and regional trains. There are three types of Frecce trains: Frecciarossa, (the fastest; connects major Italian cities); Frecciargento (mostly connect Rome to other Italian cities); and Frecciabianca (the slowest Frecce trains). Frecciarossa trains offer four classes of service, all with free Wi-Fi: Standard, Premium, Business and Executive. All Frecce tickets include a seat reservation and must be purchased before boarding the train.

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Pisa Centrale to Genova P.Za Principe
Ave. Duration
1h 54m
Frequency
Every 4 hours
Estimated price
15€ - 60€
Website
Trenitalia Frecce
Super Economy
15€ - 21€
Base Standard
30€ - 45€
Base Premium
40€ - 60€
Trenitalia Intercity

Trenitalia’s Intercity (IC) trains are slower than the high-speed Frecce trains but are still a good way to travel between major cities and towns, with routes including Rome to Naples, Venice to Bologna and Milan to Genoa. Tickets usually open for booking 90 days ahead of travel, and you’ll need make a seat reservation before boarding. All IC trains have 1st and 2nd class carriages as well as a bar buffet car, air conditioning and power sockets. InterCity trains that run at night are called InterCity Notte (ICN).

Contact Details
Phone
+39 06 68475475
Website
trenitalia.com
Train from Pisa Centrale to Genova P.Za Principe
Ave. Duration
2h 34m
Frequency
4 times a day
Estimated price
11€ - 16€
Website
Trenitalia Intercity
2nd Class
11€ - 16€
Train from Pisa Centrale to Ventimiglia
Ave. Duration
4h 27m
Frequency
Once daily
Estimated price
19€ - 27€
Website
Trenitalia Intercity
2nd Class
19€ - 27€
Thello
Phone
+33 1 83 82 00 00
Website
thello.com
Train from Genova P.Za Principe to Marseille St Charles
Ave. Duration
5h 33m
Frequency
Twice daily
Estimated price
24€ - 35€
Website
Thello
Train from Ventimiglia to Antibes
Ave. Duration
1h 1m
Frequency
Twice daily
Estimated price
9€ - 13€
Website
Thello
Train from Antibes to Marseille St Charles
Ave. Duration
2h 18m
Frequency
Twice daily
Estimated price
15€ - 22€
Website
Thello
Renfe SNCF
Website
renfe-sncf.com
Train from Marseille St Charles to Madrid-Puerta De Atocha
Ave. Duration
7h 39m
Frequency
Once daily
Estimated price
85€ - 130€
Website
renfe-sncf.com
SNCF

France’s state-owned railway company is a fast and efficient way of travelling around the country, with over 14,000 trains operating daily. SNCF runs the country’s extensive rail network, including the high-speed TGV network, regional TER trains and local Intercités. It also operates international routes including Eurostar and Thalys, as well as the low-cost, long-distance Ouigo services that run on limited routes across France. Book up to 3 months in advance for the cheapest fares. The railway network consists of about 32,000km in total, of which 1800km are high-speed lines and 14,500km are electrified.

Rome2rio's guide to SNCF
Contact Details
Phone
+33 9 70 60 99 70
Website
sncf.com
Train from Ventimiglia to Antibes
Ave. Duration
1h 28m
Frequency
Hourly
Estimated price
8€ - 22€
Website
en.oui.sncf
2nd Class
8€ - 12€
Rail 1st Class
15€ - 22€
Train from Antibes to Marseille St Charles
Ave. Duration
2h 20m
Frequency
Every 4 hours
Estimated price
25€ - 55€
Website
en.oui.sncf
2nd Class
25€ - 40€
Rail 1st Class
35€ - 55€
TGV inOui

France’s high-speed TGV train network runs at speeds of up to 320km/h connecting major cities across France and into neighbouring countries. All TGV tickets include a seat reservation; seating is 1+2 in 1st class, 2+2 in 2nd class. Popular routes include Paris to Marseille and Paris to Strasbourg. Most TGVs have a cafe area, power points at each seat and WiFi.

Contact Details
Phone
0033 892 353535
Website
en.oui.sncf
Train from Antibes to Marseille St Charles
Ave. Duration
2h 21m
Frequency
Every 4 hours
Estimated price
40€ - 55€
Website
Oui.SNCF
2nd Class
40€ - 55€
1st Class
40€ - 50€
Bus operators
FlixBus

One of Europe’s leading bus companies, Flixbus serves 2000+ destinations in 29 countries, including Germany, France, Italy, Austria, the Netherlands and Croatia and into Scandinavia and eastern Europe, as well as some US cities. Coaches have toilets, free WiFi and power outlets, plus snacks and drinks for purchase on board. Flixbus is a good choice for the budget-conscious traveller; purchase tickets in advance for the cheapest fares (note: there is no option to reserve a seat in advance).

Rome2rio's guide to FlixBus
Contact Details
Phone
+49 1807 123 99 123
Email
info@flixbus.de
Website
flixbus.de
Bus from Pisa, Pisa to Genoa, Genoa
Ave. Duration
2h 20m
Frequency
Hourly
Estimated price
10€ - 13€
Website
flixbus.co.uk
Blablabus

As the bus subsidiary of French railway SNCF, Ouibus offers eco-friendly coaches serving 35 French cities and 10 European cities at affordable fares. Ouibus journeys are safe and comfortable, with the four-star coaches offering power outlets, restrooms and WiFi. All Ouibus stations are located close to town centres for easy access to public transport. Getting on one of the 130 daily journeys is easy - electronic travel documents include your ticket and a personalised mini-guide with handy information.

Contact Details
Phone
0890715298
Website
ouibus.com
Bus from Genoa - Via Fanti d'Italia to Nice - Airport
Ave. Duration
2h 35m
Frequency
Once daily
Estimated price
10€ - 13€
Website
Blablabus
ALSA

A Spanish subsidiary of National Express, ALSA provides bus and coach services across Spain and neighbouring countries including Portugal, France, Germany, the Netherlands, Italy, Poland and Malta. Founded in 1923, ALSA values service and the customer experience. Buses are equipped with communal TV screens showing movies, individual behind-seat screens, ALSA radio, app for books and music, and free WiFi. ALSA services are accessible to people with disabilities, and guide dogs are welcome on all journeys. There are three types of tickets on offer (Frequent Traveller Pass, Share Pass and ALSA Pass), along with discounts for senior citizens, students and children.

Contact Details
Phone
+34 902 42 22 42
Website
alsa.es
Bus from Genoa - Via Fanti d'Italia to Nice - Airport
Ave. Duration
2h 25m
Frequency
Once daily
Estimated price
17€ - 24€
Website
alsa.com
Bus from Niza to Madrid
Ave. Duration
20h 45m
Frequency
Once daily
Estimated price
100€ - 150€
Website
alsa.com
Eurolines FR

Eurolines is a network of coach companies that operate throughout Europe plus Morocco. It’s an affordable way to travel around the continent, with tickets starting at €5. All coaches have Wi-Fi, plug sockets and USBs, reclining chairs and toilets, and a standard ticket includes up to two medium suitcases plus carry-on luggage. Within France, Eurolines serves 69 destinations; including Paris, Lyon, Versailles, Nice and Bordeaux.

Contact Details
Phone
+ 33 1 41 86 24 21
Website
eurolines.fr
Bus from Nice Aéroport to Madrid Est Sur
Ave. Duration
21h 5m
Frequency
Once daily
Estimated price
55€ - 80€
Website
Eurolines FR

Want to know more about travelling around Spain

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from Pisa Airport to Madrid Airport is the direct flight which takes 2h 20m.

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Pisa to Madrid bus services, operated by ALSA, arrive at Madrid station.

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Pisa to Madrid train services, operated by Renfe SNCF, arrive at Madrid-Puerta De Atocha station.

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Yes, the driving distance between Pisa to Madrid is 1623 km. It takes approximately 15h 32m to drive from Pisa to Madrid.

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Air Dolomiti, Lufthansa, Air Europa and three other airlines offer flights from Pisa Airport to Madrid Airport.

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There are 4933+ hotels available in Madrid. Prices start at 87€ per night.

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