There are 6 ways to get from Pisa to Madrid by plane, train (Trenitalia, Renfe, Ouigo), bus, car, or train (Trenitalia, TGV, Renfe)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Pisa International Airport (PSA) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane PSA - MAD
2h 35m€65–197Train via Barcelona
- Take the train from Pisa Centrale to Firenze S.M.N.train Re
- Take the train from Florence Santa Maria Novella to Milano Centraletrain
- Take the train from Milano Centrale to Lyon Part Dieutrain Fr
- Take the train from Lyon Part Dieu to Barcelona-Santstrain
- Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain Ave
18h 23m€164–448Bus
- Take the bus from Pisa to Genoabus N1508 / ...
- Take the bus from Genoa to Madridbus FlixBus N1138
25h 15m€74–206Drive 1,572 km
- Drive from Pisa to Madridcar 1,572 km
15h 40m€246–354Train
- Take the train from Pisa Centrale to Ventimigliatrain Ic
- Take the train from Nice Ville to Aix En Provence Tgvtrain Tgv
- Take the train from Aix En Provence Tgv to Madrid-Puerta de Atocha-Almudena Grandestrain
18h 28m€157–263Bus via Turin
- Take the bus from PISA - Via Pietrasantina Parcheggio to Turinbus Reggio Calabria
- Take the bus from Turin Corso Vittorio Emanuele II to Madrid Mendez Alvaro Estacion Surbus Union Ivkoni - Unibus 3415 / ...
31h 5m€87–119
Pisa to Madrid by train
Questions & Answers
The cheapest way to get from Pisa to Madrid is to bus via Turin which costs €85 - €120 and takes 31h 5m.
The fastest way to get from Pisa to Madrid is to fly which takes 2h 35m and costs €65 - €200.
No, there is no direct bus from Pisa to Madrid. However, there are services departing from Pisa and arriving at Madrid via Genoa. The journey, including transfers, takes approximately 25h 15m.
No, there is no direct train from Pisa to Madrid. However, there are services departing from Pisa Centrale and arriving at Madrid-Puerta de Atocha-Almudena Grandes via Florence Santa Maria Novella, Milano Centrale, Lyon Part Dieu and Barcelona-Sants. The journey, including transfers, takes approximately 18h 23m.
The distance between Pisa and Madrid is 1216 km. The road distance is 1572 km.
The best way to get from Pisa to Madrid without a car is to train via Barcelona which takes 18h 23m and costs €160 - €450.
It takes approximately 2h 35m to get from Pisa to Madrid, including transfers.
Pisa to Madrid bus services, operated by FlixBus, depart from Pisa station.
Pisa to Madrid train services, operated by Trenitalia, depart from Pisa Centrale station.
The best way to get from Pisa to Madrid is to fly which takes 2h 35m and costs €65 - €200. Alternatively, you can train via Barcelona, which costs €160 - €450 and takes 18h 23m, you could also bus, which costs €70 - €210 and takes 25h 15m.
What companies run services between Pisa, Italy and Madrid, Spain?
Ryanair flies from Pisa International Airport (PSA) to Adolfo Suárez Madrid–Barajas Airport (MAD) 5 times a week. Alternatively, you can take a train from Pisa Centrale to Madrid-Puerta de Atocha-Almudena Grandes via Florence Santa Maria Novella, Milano Centrale, Lyon Part Dieu, and Barcelona-Sants in around 18h 23m.
- Website
- ryanair.com
Flights from Pisa International Airport to Adolfo Suárez Madrid–Barajas Airport
- Ave. Duration
- 2h 10m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €55–190
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Pisa Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 22m
- Frequency
- Every 30 minutes
- Estimated price
- €9–24
- Website
- https://www.trenitalia.com/en.html
Train from Milano Centrale to Lyon Part Dieu
- Ave. Duration
- 4h 39m
- Frequency
- Twice daily
- Estimated price
- €50–150
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €26–70
- Website
- https://www.italotreno.it/en
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Lyon Part Dieu to Barcelona-Sants
- Ave. Duration
- 4h 48m
- Frequency
- Once daily
- Estimated price
- €50–75
- Website
- https://www.renfe.com/es/en
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 2m
- Frequency
- Twice daily
- Estimated price
- €45–65
- Website
- https://www.renfe.com/es/en
Train from Aix En Provence Tgv to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 7h 34m
- Frequency
- Once daily
- Estimated price
- €90–120
- Website
- https://www.renfe.com/es/en
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 2h 37m
- Frequency
- Hourly
- Estimated price
- €35–130
- Website
- https://www.renfe.com/es/en
- Phone
- +34 900 926 851
- atencion.cliente@iryo.eu
- Website
- iryo.eu
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 2h 59m
- Frequency
- Hourly
- Estimated price
- €35–110
- Website
- https://iryo.eu/en/home
- Phone
- +34 910 780 990
- Website
- ouigo.com
Train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 3h 3m
- Frequency
- 5 times a day
- Estimated price
- €29–60
- Website
- https://www.ouigo.com/es/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Pisa Centrale to Ventimiglia
- Ave. Duration
- 4h 36m
- Frequency
- Once daily
- Estimated price
- €25–45
- Website
- https://www.trenitalia.com/en.html
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Nice Ville to Aix En Provence Tgv
- Ave. Duration
- 2h 59m
- Frequency
- 3 times a day
- Estimated price
- €30–55
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Nice Ville to Aix En Provence Tgv
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- €40–90
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €40–60
- Rail 1st Class
- €60–90
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Pisa to Genoa
- Ave. Duration
- 3h 15m
- Frequency
- 4 times a day
- Estimated price
- €9–16
- Website
- https://www.flixbus.co.uk
Bus from Genoa to Madrid
- Ave. Duration
- 21h
- Frequency
- Twice daily
- Estimated price
- €65–190
- Website
- https://www.flixbus.co.uk
- Phone
- 0966 57552
- info@lirosiautoservizi.com
- Website
- lirosiautoserviziorari.com
Bus from PISA - Via Pietrasantina Parcheggio to Turin
- Ave. Duration
- 5h 55m
- Frequency
- 5 times a week
- Estimated price
- €21–24
- Schedules at
- lirosiautoserviziorari.com
- Phone
- 07001 8282
- booking@union-ivkoni.com
- Website
- union-ivkoni.com
Bus from Turin Corso Vittorio Emanuele II to Madrid Mendez Alvaro Estacion Sur
- Ave. Duration
- 24h
- Frequency
- Twice a week
- Estimated price
- €65–95
- Website
- https://union-ivkoni.com/en
Want to know more about travelling around Spain
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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More Questions & Answers
Pisa to Madrid bus services, operated by FlixBus, arrive at Genoa station.
Pisa to Madrid train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Pisa to Madrid is 1572 km. It takes approximately 15h 40m to drive from Pisa to Madrid.
Book your Pisa to Madrid train tickets online with Omio.
Book your Pisa to Madrid bus tickets online with Omio and FlixBus.
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