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How to get fromPilsen to Mainzby bus, train, car, or plane

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There are 9 ways to get from Pilsen to Mainz by bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Plzeň,Terminál Hlavní nádraží to Nürnbergbus bus Ivano-Frankivsk
    2. Take the train from Nürnberg Hbf to Frankfurttrain train 41
    5h 57m

  2. Bus

    cheapest
    1. Take the bus from Pilsen to Frankfurt am Mainbus bus
    8h 3m
    €23–43

  3. Bus via Frankfurt

    1. Take the bus from Pilsen Central Bus Station to Frankfurt Main Airport P36bus bus : Amsterdam Central Sloterdijk Train Station - Prague Central Bus Station / ...
    6h 35m
    €38–63

  4. Drive 447.1 km

    1. Drive from Pilsen to Mainzcar car 447.1 km
    3h 38m
    €70–101

  5. Bus to Václav Havel Airport Prague, fly

    1. Take the bus from Plzeň to Praguebus bus
    2. Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)plane plane PRG - FRA
    4h 48m
    €67–175

  6. Train

    1. Take the train from Plzen Hlavni Nadrazi to Schwandorftrain train Ec
    2. Take the train from Schwandorf to Nürnberg Hbftrain train
    3. Take the train from Nürnberg Hbf to Frankfurttrain train 41 / ...
    7h 19m
    €96–266

  7. Bus to Nuremberg Airport, fly

    1. Take the bus from Plzeň,Terminál Hlavní nádraží to Nürnbergbus bus
    2. Fly from Nuremberg Airport (NUE) to Frankfurt (FRA)plane plane NUE - FRA
    4h 54m

  8. Bus to Dresden Airport, fly

    1. Take the bus from Plzeň,Terminál Hlavní nádraží to Dresdenbus bus
    2. Fly from Dresden Airport (DRS) to Frankfurt (FRA)plane plane DRS - FRA
    5h 13m

  9. Train to Munich International Airport, fly

    1. Take the train from Plzen Hlavni Nadrazi to Freisingtrain train
    2. Fly from Munich International Airport (MUC) to Frankfurt (FRA)plane plane MUC - FRA
    6h 31m
    €143–302

Pilsen to Mainz by bus and foot

Calendar17Weekly Services
Duration6h 35mAverage Duration
Ticket€38Cheapest Price
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Questions & Answers

Map of how to get from Pilsen to Mainz.ExpandLaunch map view
  • Distance: 458.6 km
  • Duration: 5h 57m

What companies run services between Pilsen, Czechia and Mainz, Germany?

RegioJet operates a bus from Pilsen Central Bus Station to Frankfurt Main Airport P36 once daily. Tickets cost €30–50 and the journey takes 5h 35m. FlixBus also services this route once daily. Alternatively, you can take a train from Plzen Hlavni Nadrazi to Mainz, Römisches Theater via Schwandorf, Nürnberg Hbf, and Frankfurt in around 7h 19m.

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