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How to get fromRome to Mainzby plane, train (Trenitalia), bus, car, or train

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There are 7 ways to get from Rome to Mainz by plane, train (Trenitalia), bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Frankfurt

    best
    1. Fly from Fiumicino International Airport (FCO) to Frankfurt (FRA)plane plane FCO - FRA
    4h 55m
    €59–159

  2. Train

    1. Take the train from Roma Termini to Milano Centraletrain train
    2. Take the train from Milano Centrale to Mannheim Hbftrain train Ec
    3. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train 55 / ...
    11h 47m
    €207–372

  3. Bus

    1. Take the bus from Roma Prenestina A1 to Wiesbaden Gartenfeldstraße P+Rbus bus
    18h 12m

  4. Drive 1,231.4 km

    1. Drive from Rome to Mainzcar car 1,231.4 km
    11h 29m
    €196–283

  5. Fly to Stuttgart Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Stuttgart Airport (STR)plane plane FCO - STR
    2. Take the train from Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    3. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train
    6h 37m
    €96–322

  6. Train via Mainz, Römisches Theater

    1. Take the train from Roma Termini to Milano Centraletrain train Fr / ...
    2. Take the train from Milano Centrale to Mannheim Hbftrain train Ec
    3. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    12h 38m
    €204–362

  7. Bus via Frankfurt am Main

    1. Take the bus from Roma, Autostazione Tiburtina to Frankfurt central train stationbus bus N77
    21h 48m
    €114–190

Rome to Mainz by train

Calendar7Weekly Trains
Duration12h 38mAverage Duration
Ticket€204Cheapest Price
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Questions & Answers

Map of how to get from Rome to Mainz.ExpandLaunch map view
  • Distance: 1,018.9 km
  • Duration: 4h 55m

What companies run services between Rome, Italy and Mainz, Germany?

ITA Airways, easyJet, and two other airlines fly from Fiumicino International Airport (FCO) to Frankfurt (FRA) hourly. Alternatively, you can take a train from Roma Termini to Mainz, Hauptbahnhof via Milano Centrale, Mannheim Hbf, and Mannheim, Hauptbahnhof in around 11h 47m.

Airlines
Train operators
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Want to know more about travelling around Germany

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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