There are 6 ways to get from Rome to Mainz by plane, train (Trenitalia), bus, night train, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Fiumicino International Airport (FCO) to Frankfurt (FRA)plane FCO - FRA
4h 59m€56–239Train
- Take the train from Roma Termini to Milano Centraletrain
- Take the train from Milano Centrale to Mannheim Hbftrain Ec
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
12h 32m€213–359Bus, night train, train
- Take the bus from Roma to Zurigobus
- Take the night train from Zuerich Hb to Mannheim Hbfnighttrain Nj
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain S5 / ...
21h 9m€91–210Night train, train
- Take the night train from Roma Tiburtina to Muenchen Hbfnighttrain En
- Take the train from München Hbf to Frankfurttrain 47 / ...
19h 37m€250–475Bus
- Take the bus from Roma, Autostazione Tiburtina to Frankfurt central train stationbus N77
22h 35m€96–163Drive 1,231.3 km
- Drive from Rome to Mainzcar 1,231.3 km
11h 29m€191–276
Rome to Mainz by night train and train
Questions & Answers
The cheapest way to get from Rome to Mainz is to fly which costs €55 - €240 and takes 4h 59m.
The fastest way to get from Rome to Mainz is to fly which takes 4h 59m and costs €55 - €240.
No, there is no direct bus from Rome to Mainz station. However, there are services departing from Roma, Autostazione Tiburtina and arriving at Mainz central train station via Frankfurt central train station. The journey, including transfers, takes approximately 22h 35m.
No, there is no direct train from Rome to Mainz. However, there are services departing from Roma Termini and arriving at Mainz, Römisches Theater via Milano Centrale and Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 12h 32m.
The distance between Rome and Mainz is 1019 km. The road distance is 1231.3 km.
The best way to get from Rome to Mainz without a car is to train which takes 12h 32m and costs €210 - €360.
It takes approximately 4h 59m to get from Rome to Mainz, including transfers.
Rome to Mainz bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
Rome to Mainz train services, operated by ItaloTreno, depart from Roma Termini station.
The best way to get from Rome to Mainz is to fly which takes 4h 59m and costs €55 - €240. Alternatively, you can train, which costs €210 - €360 and takes 12h 32m, you could also bus, which costs €95 - €170 and takes 22h 35m.
What companies run services between Rome, Italy and Mainz, Germany?
easyJet, Condor Flugdienst, and two other airlines fly from Fiumicino International Airport (FCO) to Frankfurt (FRA) hourly. Alternatively, you can take a train from Roma Termini to Mainz, Römisches Theater via Milano Centrale, Mannheim Hbf, and Mannheim, Hauptbahnhof in around 12h 32m.
- Website
- lufthansa.com
Flights from Fiumicino International Airport to Frankfurt
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- €65–310
Flights from Fiumicino International Airport to Frankfurt via Munich
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- €85–310
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Frankfurt
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- €65–310
- Website
- condor.com
Flights from Fiumicino International Airport to Frankfurt
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €50–230
- Website
- easyjet.com
Flights from Fiumicino International Airport to Frankfurt
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- €45–160
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- €75–160
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Milano Centrale to Mannheim Hbf
- Ave. Duration
- 6h 48m
- Frequency
- Once daily
- Estimated price
- €120–180
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €120–180
- 2nd Class
- €120–160
Night train from Roma Tiburtina to Muenchen Hbf
- Ave. Duration
- 15h 23m
- Frequency
- Once daily
- Estimated price
- €190–280
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €190–280
- 2nd Class
- €210–280
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €19–27
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 57 min
- Frequency
- 5 times a week
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +43 51717
- Website
- nightjet.com
Night train from Zuerich Hb to Mannheim Hbf
- Ave. Duration
- 4h 21m
- Frequency
- Once a week
- Estimated price
- €27–95
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €93–95
- Couchette Carriage
- €55–70
- Seating Carriage
- €27–33
.jpg "Nightjet train Innsbruck Hbf")
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from München Hbf to Frankfurt
- Ave. Duration
- 3h 19m
- Frequency
- Every 30 minutes
- Estimated price
- €80–190
- Website
- https://int.bahn.de/en
#/media/File:ICE_4_Berlin_Hauptbahnhof_(3).jpg "ICE 4 Berlin Hauptbahnhof")
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from München Hbf to Frankfurt
- Ave. Duration
- 3h 18m
- Frequency
- Once daily
- Estimated price
- €45–110
- Website
- https://www.ns.nl/en
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Roma to Zurigo
- Ave. Duration
- 14h
- Frequency
- Every 2 hours
- Estimated price
- €50–90
- Website
- https://www.itabus.it/en/home
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Roma, Autostazione Tiburtina to Frankfurt central train station
- Ave. Duration
- 20h 55m
- Frequency
- Once daily
- Estimated price
- €90–160
- Website
- https://www.flixbus.co.uk
Want to know more about travelling around Germany
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More Questions & Answers
Rome to Mainz bus services, operated by FlixBus, arrive at Frankfurt central train station.
Rome to Mainz train services, operated by ItaloTreno, arrive at Milano Centrale station.
Yes, the driving distance between Rome to Mainz is 1231 km. It takes approximately 11h 29m to drive from Rome to Mainz.
Book your Rome to Mainz bus tickets online with FlixBus.
There are 413+ hotels available in Mainz.