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How to get fromNatick to Buffaloby train, plane, bus (Greyhound, Flixbus), train (Amtrak), car or bus

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There are 6 ways to get from Natick to Buffalo by train, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, fly to Buffalo Niagara International Airport

    best
    1. Take the train from Natick Center to South Stationtrain
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)planeBOS - BUF
    4h 58m
    $158–1,066
  2. Bus

    cheapest
    1. Take the bus from Boston, MA to Syracuse, NYbusOurBus
    2. Take the bus from Syracuse, NY to Buffalo, NYbusOurBus
    13h 2m
    $46–171
  3. Bus via Springfield

    1. Take the bus from Framingham to Springfield Union Stationbus
    2. Take the bus from Springfield Union Station to Syracuse Bus Stationbus
    3. Take the bus from Syracuse Bus Station to Buffalobus
    11h 48m
    $89–161
  4. Train (Amtrak)

    1. Take the train from Framingham Amtrak to Buffalo Depew StationtrainLake Shore Limited
    13h 35m
    $56–241
  5. Drive 438.9 mi

    1. Drive from Natick to Buffalocar438.9 mi
    7h 38m
    $81–116
  6. Fly to Rochester, bus

    1. Fly from Boston Logan Airport (BOS) to Rochester (ROC)planeBOS - ROC
    2. Take the bus from Rochester, NY to Buffalo, NYbus
    6h 57m
    $218–671

Natick to Buffalo by train and bus

Calendar14Weekly Services
Duration11h 48mAverage Duration
Ticket$89Cheapest Price
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Questions & Answers

What companies run services between Natick, MA, USA and Buffalo, NY, USA?

You can take a train from Natick Center to Buffalo via Framingham, Framingham, Springfield Union Station, and Syracuse Bus Station in around 11h 48m. Alternatively, Amtrak operates a train from Framingham Amtrak to Buffalo Depew Station once daily. Tickets cost $45–160 and the journey takes 11h 4m.

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