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How to get fromCary to Buffaloby bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train

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There are 6 ways to get from Cary to Buffalo by bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 310 bus, fly to Buffalo Niagara International Airport

    best
    1. Take the bus from Cary Depot to Regional Transit Centerbus bus
    2. Fly from Raleigh-Durham International Airport (RDU) to Buffalo Niagara International Airport (BUF)plane plane RDU - BUF
    4h 36m
    $128–454

  2. Drive 587.9 mi

    cheapest
    1. Drive from Cary to Buffalocar car 587.9 mi
    13h 8m
    $108–155

  3. Bus

    1. Take the bus from Raleigh Bus Station to Newark Penn Stationbus bus Greyhound US0670 / ...
    2. Take the bus from Newark Penn Station to Buffalobus bus FlixBus 2686 / ...
    19h 55m
    $134–264

  4. Train (Amtrak)

    1. Take the train from Cary to Ny Moynihan Train Hall At Penn Stationtrain train Carolinian
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    20h 23m
    $311–642

  5. Fly to Rochester, bus

    1. Fly from Raleigh-Durham International Airport (RDU) to Rochester (ROC)plane plane RDU - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 53m
    $154–950

  6. Train, bus

    1. Take the train from Cary to Pittsburgh Amtrak Stationtrain train Floridian
    2. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    23h 57m
    $236–585

Cary to Buffalo by bus and foot

Calendar42Weekly Services
Duration19h 55mAverage Duration
Ticket$134Cheapest Price
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Questions & Answers

Map of how to get from Cary to Buffalo.ExpandLaunch map view
  • Distance: 515.4 mi
  • Duration: 4h 36m

What companies run services between Cary, NC, USA and Buffalo, NY, USA?

You can take a bus from Cary Depot to Buffalo via Union Station - Bus Platform A, GoRaleigh Station, Capital Blvd at Crabtree Blvd, Raleigh Bus Station, and Newark Penn Station in around 19h 55m. Alternatively, you can take a train from Cary to Buffalo via Ny Moynihan Train Hall At Penn Station in around 20h 23m.

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