There are 7 ways to get from Mytilene to Lyon by plane, car ferry, bus, train, car, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Mytilene International Airport Odysseas Elytis (MJT) to Lyon–Saint Exupéry Airport (LYS)plane MJT - LYS
5h 58m€153–305Car ferry, bus, train
- Take the car ferry from Mytilene to Port of Thessalonikicarferry
- Take the bus from Thessaloniki to Skopje Central Bus Stationbus
- Take the bus from Skopje, Transporten Centar to Bologna Centralebus
- Take the train from Bologna centrale to Milano Centraletrain
- Take the train from Milano Centrale to Lyon Part Dieutrain Fr
35h 21m€363–663Car ferry, bus, train via Budapest
- Take the car ferry from Mytilene to Port of Thessalonikicarferry
- Take the bus from Thessaloníki to Budapestbus
- Take the train from Budapest-Keleti to Zuerich Hbtrain Rjx
- Take the train from Zürich HB to Mulhousetrain Tgv
- Take the train from Mulhouse Ville to Lyon Part Dieutrain 84
44h 25m€432–935Car ferry, drive
- Take the car ferry from Mytilene to Port of Thessalonikicarferry
- Drive from Port of Thessaloniki to Lyoncar
26h 52m€505–913Ferry, bus
- Take the ferry from Mytilene to Thessalonikiferry Bsf
- Take the bus from Thessaloníki to Prizren,Autobuska Stanicabus
- Take the bus from Prizren,Autobuska Stanica to Geneva - Bus stationbus
- Take the bus from Geneva to Lyonbus
43h 10m€175–284Ferry, bus via Bursa
- Take the ferry from Mytilene to Port of Ayvalikferry
- Take the bus from Ayvalık to Bursabus
- Take the bus from Bursa to Xánthibus
- Take the bus from Xánthi to Tiranabus
- Take the bus from Tirana to Lyon Part Dieubus
2d 2hFerry, bus via Tirana
- Take the ferry from Mytilene to Thessalonikiferry Bsf
- Take the bus from Thessaloníki to Tiranabus
- Take the bus from Tirana to Lyon, Perrache Bus Stationbus
2d 3h
Mytilene to Lyon by car ferry, foot, bus, subway, and train
Questions & Answers
The cheapest way to get from Mytilene to Lyon is to ferry and bus which costs €170 - €290 and takes 43h 10m.
The fastest way to get from Mytilene to Lyon is to fly which takes 5h 58m and costs €150 - €310.
The distance between Mytilene and Lyon is 1939 km.
The best way to get from Mytilene to Lyon without a car is to car ferry and bus and train which takes 35h 21m and costs €360 - €700.
It takes approximately 5h 58m to get from Mytilene to Lyon, including transfers.
Lyon is 1h behind Mytilene. It is currently 10:17 PM in Mytilene and 9:17 PM in Lyon.
There are 1304+ hotels available in Lyon.
What companies run services between Mytilene, Greece and Lyon, France?
Sky Express, Aegean Airlines, and two other airlines fly from Mytilene International Airport Odysseas Elytis (MJT) to Lyon–Saint Exupéry Airport (LYS) twice daily.
- Website
- en.aegeanair.com
Flights from Mytilene International Airport Odysseas Elytis to Lyon–Saint Exupéry Airport via Athens
- Ave. Duration
- 5h 55m
- When
- Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €80–340
Flights from Mytilene International Airport Odysseas Elytis to Lyon–Saint Exupéry Airport via Heraklion
- Ave. Duration
- 6h
- When
- Thursday
- Estimated price
- €95–350
- Website
- skyexpress.gr
Flights from Mytilene International Airport Odysseas Elytis to Lyon–Saint Exupéry Airport via Athens
- Ave. Duration
- 5h 45m
- When
- Monday and Friday
- Estimated price
- €120–260
- Website
- transavia.com
Flights from Mytilene International Airport Odysseas Elytis to Lyon–Saint Exupéry Airport via Athens
- Ave. Duration
- 5h 5m
- When
- Saturday
- Estimated price
- €90–440
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Bologna centrale to Milano Centrale
- Ave. Duration
- 1h 4m
- Frequency
- Every 30 minutes
- Estimated price
- €28–55
- Website
- https://www.italotreno.it/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Milano Centrale to Lyon Part Dieu
- Ave. Duration
- 4h 47m
- Frequency
- Twice daily
- Estimated price
- €55–100
- Website
- https://www.trenitalia.com/en.html
Train from Budapest-Keleti to Zuerich Hb
- Ave. Duration
- 10h 40m
- Frequency
- Once daily
- Estimated price
- €130–210
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/railjet
- *
- €130–200
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Zürich HB to Mulhouse
- Ave. Duration
- 1h 19m
- Frequency
- Every 4 hours
- Estimated price
- €40–120
- Website
- https://www.sbb.ch/en
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact Details
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Mulhouse Ville to Lyon Part Dieu
- Ave. Duration
- 2h 49m
- Frequency
- Once daily
- Estimated price
- €55–150
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +30-2310540970
- info@simeonidistours.gr
- Website
- simeonidistours.gr
Bus from Thessaloniki to Skopje Central Bus Station
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- €25–35
- Website
- https://simeonidistours.gr/en/
- Phone
- +389 75 209 209
- hakkomerc@gmail.com
- Website
- hakbus.org
Bus from Skopje, Transporten Centar to Bologna Centrale
- Ave. Duration
- 14h 48m
- Frequency
- Once a week
- Estimated price
- €110
- Website
- https://www.hakbus.org/
- Phone
- +302105233969
- fptravel@otenet.gr
- Website
- fptravel.gr
Bus from Thessaloníki to Budapest
- Ave. Duration
- 17h 45m
- Frequency
- 4 times a week
- Estimated price
- €60–90
- Schedules at
- fptravel.gr
- Phone
- + 383 (0) 44 542 029
- info@sharrtravel.com
- Website
- sharrtravel.com
Bus from Thessaloníki to Prizren,Autobuska Stanica
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- €20
- Website
- https://www.sharrtravel.com
- Phone
- +383 49 871 234
- ardititours@hotmail.com
- Website
- sr-rs.facebook.com
Bus from Prizren,Autobuska Stanica to Geneva - Bus station
- Ave. Duration
- 22h 5m
- Frequency
- Twice a week
- Estimated price
- €75–90
- Website
- https://sr-rs.facebook.com/ardititours/
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Geneva to Lyon
- Ave. Duration
- 2h 15m
- Frequency
- Hourly
- Estimated price
- €10–19
- Website
- https://www.flixbus.co.uk
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Geneva to Lyon
- Ave. Duration
- 2h 30m
- Frequency
- Every 2 hours
- Estimated price
- €10–20
- Website
- https://www.blablacar.co.uk/bus
- Phone
- 0 850 333 35 35
- info@pamukkale.com.tr
- Website
- pamukkale.com.tr
Bus from Ayvalık to Bursa
- Ave. Duration
- 4h
- Frequency
- Twice daily
- Estimated price
- €10–13
- Schedules at
- pamukkale.com.tr
- Phone
- +30 2310241545
- crazy.holidays.tours@gmail.com
- Website
- crazyholidays.gr
Bus from Bursa to Xánthi
- Ave. Duration
- 9h
- Frequency
- Twice a week
- Estimated price
- €35–80
- Website
- https://www.crazyholidays.gr/root.en.aspx
- Phone
- +355 699 605501
- startravel@live.com
- Website
- facebook.com
Bus from Xánthi to Tirana
- Ave. Duration
- 12h
- Frequency
- Once daily
- Schedules at
- facebook.com
- Phone
- +355 69 232 8000
- anumitravel@gmail.com
- Website
- facebook.com
Bus from Tirana to Lyon Part Dieu
- Ave. Duration
- 20h 57m
- Frequency
- Once a week
- Schedules at
- facebook.com
- Phone
- +355 67 604 2191
- Website
- facebook.com
Bus from Thessaloníki to Tirana
- Ave. Duration
- 8h
- Frequency
- Twice daily
- Schedules at
- autobus.al
- Phone
- +355 68 20 63 724
- info@arjanitravel.com
- Website
- arjanitravel.com
Bus from Tirana to Lyon, Perrache Bus Station
- Ave. Duration
- 31h
- Frequency
- Once a week
- Schedules at
- arjanitravel.com
- Phone
- +30 210 710 7 710
- info@seajets.gr
- Website
- seajets.com
Car ferry from Mytilene to Port of Thessaloniki
- Ave. Duration
- 7h 10m
- Frequency
- Once a week
- Estimated price
- €140–370
- Website
- https://www.seajets.com/
Ferry from Mytilene to Thessaloniki
- Ave. Duration
- 10h 5m
- Frequency
- Once a week
- Estimated price
- €70–160
- Website
- https://www.bluestarferries.com/en-gb/
- Phone
- 0545 783 50 61
- info@jalemtur.com
- Website
- jalemtur.com
Ferry from Mytilene to Port of Ayvalik
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- €38–40
- Schedules at
- jalemtur.com
Want to know more about travelling around France
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Italy Travel Guides
Read the travel guide
Train travel in France: A guide to SNCF
Read the travel guide



































































