There are 4 ways to get from Mytilene to Istanbul by car ferry, bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Carferry, bus MetroTurizm  •  10 h 16 min

  1. Take the carferry from Mitilini to Ayvalık
  2. Take the bus from Ayvalik to Istanbul Otogari

$25 - $43

3 alternative options

Carferry, bus Kamil Koc  •  12 h 41 min

  1. Take the carferry from Mitilini to Ayvalık
  2. Take the bus from Burhaniye to Istanbul

$29 - $47

Carferry, drive  •  6 h 43 min

  1. Take the carferry from Mitilini to Ayvalık
  2. Drive from Ayvalık to Istanbul

$65 - $104

Fly  •  4 h 38 min

  1. Fly from Mytilini (MJT) to Istanbul Ataturk (IST) MJT - IST

$62 - $244

Questions & Answers

The distance between Mytilene and Istanbul is 294 km.

The best way to get from Mytilene to Istanbul without a car is to carferry and bus which takes 10 h 16 min and costs .

More details

It takes approximately 10 h 16 min to get from Mytilene to Istanbul, including transfers.

More details

There is no direct flight from Mytilini Airport to Istanbul Ataturk Airport. The quickest flight takes 3 h 55 min and has one stopover.

Search flights

Istanbul is 1 h ahead of Mytilene. It is currently 5:43 AM in Mytilene and 5:43 AM in Istanbul.

Sky Express , Turkish Airlines, Aegean Airlines and Olympic Air offer flights from Mytilini Airport to Istanbul Ataturk Airport.

Search flights

There are 2274+ hotels available in Istanbul. Prices start at $38 USD per night.

More details

The best way to get from Mytilene to Mytilini Airport is to taxi which takes 8 min and costs .

More details

Map of how to get from Mytilene to Istanbul.
Launch map view
  • Distance: 183.7 miles
  • Duration: 10 h 16 min

What companies run services between Mytilene, Greece and Istanbul, Turkey?

Olympic Air, Turkish Airlines and two other airlines fly from Mytilene to Istanbul every 4 hours.

Airlines
Aegean Airlines
Website
aegeanair.com
Flights from Mytilini to Istanbul Ataturk via Athens
Ave. Duration
4 h 55 min
When
Every day
Estimated price
$75 - $390
Flights from Mytilini to Istanbul Ataturk via Thessaloniki, Athens
Ave. Duration
7 h 30 min
When
Tuesday, Thursday, Friday and Sunday
Estimated price
$65 - $340
Bus operators
MetroTurizm
Phone
0850 222 34 55
Email
iletisim@metroturizm.com.tr
Website
metroturizm.com.tr
Bus from Ayvalik to Istanbul Otogari
Ave. Duration
7 h 26 min
Frequency
4 times a day
Estimated price
$9 - $18
Schedules at
metroturizm.com.tr
Kamil Koc
Phone
+90 224 294 55 62
Website
kamilkoc.com.tr
Bus from Ayvalık to Istanbul
Ave. Duration
8 h 57 min
Frequency
5 times a day
Estimated price
$9 - $14
Schedules at
kamilkoc.com.tr
Bus from Burhaniye to Istanbul
Ave. Duration
8 h 2 min
Frequency
5 times a day
Estimated price
$8 - $14
Schedules at
kamilkoc.com.tr
Ferry operators
Jale Tour
Phone
+90266 331 31 70
Email
info@jaletur.com
Website
jaletour.com
Car ferry from Mitilini to Ayvalık
Ave. Duration
1 h 30 min
Frequency
Once daily
Estimated price
$15 - $24
Schedules at
jaletour.com

Want to know more about travelling around the world?

Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including South Korea: Travelling from Seoul to Busan , Getting to Rome from the airport and Which side of Niagara Falls should I choose (and how do I get there)? - to help you get the most out of your next trip.