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How to get fromMobile to Des Moinesby bus, plane, train, or car

Find Transport to Des Moines

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There are 7 ways to get from Mobile to Des Moines by bus, plane, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Destin–Fort Walton Beach Airport, fly

    best
    1. Take the bus from Mobile to Crestviewbus bus
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Des Moines (DSM)plane plane VPS - DSM
    5h 39m
    $276–997
  2. Drive 957.6 mi

    cheapest
    1. Drive from Mobile to Des Moinescar car 957.6 mi
    18h 6m
    $175–253
  3. Train, bus

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train
    2. Take the bus from New Orleans Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Des Moinesbus bus
    28h 48m
    $205–458
  4. Train, bus via Champaign

    1. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train
    2. Take the train from New Orleans Union Passenger Terminal to Champaign-Urbanatrain train
    3. Take the bus from Champaign Intermodal Trans Ctr to Des Moinesbus bus
    30h 3m
    $315–698
  5. Fly from Mobile Regional Airport

    1. Fly from Mobile Regional Airport (MOB) to Des Moines (DSM)plane plane MOB - DSM
    7h 42m
    $207–936
  6. Train to Gulfport-Biloxi Regional Airport, fly

    1. Take the train from Mobile Amtrak Sta to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Des Moines (DSM)plane plane GPT - DSM
    7h 41m
    $283–1,284
  7. Bus to Pensacola International Airport, fly

    1. Take the bus from Mobile Bus Station to Pensacola Airportbus bus
    2. Fly from Pensacola International Airport (PNS) to Des Moines (DSM)plane plane PNS - DSM
    8h 8m
    $207–990

Destin–Fort Walton Beach Airport (VPS) to Des Moines (DSM) flights

Calendar15Weekly Planes
Duration3h 24mAverage Duration
Ticket$163Cheapest Price
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Questions & Answers

What companies run services between Mobile, AL, USA and Des Moines, IA, USA?

Delta, United Airlines, and American Airlines fly from Mobile Regional Airport (MOB) to Des Moines (DSM) every 4 hours.

Airlines
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Bus operators

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