There are 8 ways to get from Mobile to Des Moines by bus, plane, bus (Greyhound, Flixbus), train, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Destin–Fort Walton Beach Airport, fly
best- Take the bus from Mobile to Crestview
- Fly from Destin–Fort Walton Beach Airport (VPS) to Des Moines (DSM)VPS - DSM
5h 46m$256–947Bus via New South Memphis
cheapest- Take the bus from Mobile Bus Station to Lafayette
- Take the bus from Lafayette to Memphis Bus Station
- Take the bus from Memphis Bus Station to Kansas City
- Take the bus from Kansas City to Des Moines
32h 17m$157–460Bus
- Take the bus from Mobile Bus Station to New Orleans Bus Station
- Take the bus from New Orleans Bus Station to St Louis Bus Station
- Take the bus from St Louis to Burlington
- Take the bus from Burlington to Des Moines
29h 37m$178–375Bus, train
- Take the bus from Mobile Bus Station to New Orleans Bus Station
- Take the train from New Orleans Union Passenger Terminal to Champaign-Urbana
- Take the bus from Champaign to Des Moines
31h 52m$198–415Drive 957.6 mi
- Drive from Mobile to Des Moines957.6 mi
18h 10m$175–253Fly from Mobile Regional Airport
- Fly from Mobile Regional Airport (MOB) to Des Moines (DSM)MOB - DSM
8h 19m$184–840Bus to Pensacola International Airport, fly
- Take the bus from Mobile Bus Station to Pensacola Airport
- Fly from Pensacola International Airport (PNS) to Des Moines (DSM)PNS - DSM
8h 31m$213–974Bus to Gulfport-Biloxi Regional Airport, fly
- Take the bus from Mobile to Gulfport
- Fly from Gulfport-Biloxi Regional Airport (GPT) to Des Moines (DSM)GPT - DSM
9h$306–1,099
Mobile to Des Moines by bus
Questions & Answers
The cheapest way to get from Mobile to Des Moines is to drive which costs $170 - $260 and takes 18h 10m.
The fastest way to get from Mobile to Des Moines is to bus and fly which takes 5h 46m and costs $250 - $950.
No, there is no direct bus from Mobile to Des Moines. However, there are services departing from St Joseph SB Near St Louis St and arriving at Des Moines via Mobile Bus Station, New Orleans Bus Station, St Louis and Burlington. The journey, including transfers, takes approximately 29h 37m.
The distance between Mobile and Des Moines is 1005 miles. The road distance is 963.2 miles.
The best way to get from Mobile to Des Moines without a car is to bus which takes 29h 37m and costs $170 - $380.
It takes approximately 5h 46m to get from Mobile to Des Moines, including transfers.
Mobile to Des Moines bus services, operated by Greyhound USA, depart from Mobile Bus Station.
The best way to get from Mobile to Des Moines is to bus which takes 29h 37m and costs $170 - $380. Alternatively, you can fly, which costs $180 - $850 and takes 8h 19m.
Mobile to Des Moines bus services, operated by Greyhound USA, arrive at New Orleans Bus Station.
Yes, the driving distance between Mobile to Des Moines is 963 miles. It takes approximately 18h 10m to drive from Mobile to Des Moines.
What companies run services between Mobile, AL, USA and Des Moines, IA, USA?
You can take a bus from St Joseph SB Near St Louis St to Des Moines via Govt WB Across from Greyhound, Mobile Bus Station, New Orleans Bus Station, St Louis, and Burlington in around 29h 37m. Alternatively, Delta, American Airlines, and United Airlines fly from Mobile Regional Airport (MOB) to Des Moines (DSM) every 3 hours.
- Website
- delta.com
Flights from Destin–Fort Walton Beach Airport to Des Moines via Atlanta
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $160–800
Flights from Mobile Regional Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 14m
- When
- Every day
- Estimated price
- $160–850
Flights from Pensacola International Airport to Des Moines via Atlanta
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $180–950
Flights from Gulfport-Biloxi Regional Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 41m
- When
- Monday, Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $190–950
- Website
- aa.com
Flights from Mobile Regional Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 6h 8m
- When
- Every day
- Estimated price
- $180–900
Flights from Mobile Regional Airport to Des Moines via Charlotte
- Ave. Duration
- 6h 48m
- When
- Every day
- Estimated price
- $190–950
Flights from Pensacola International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 10m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- $190–1,000
Flights from Pensacola International Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 6h 51m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Gulfport-Biloxi Regional Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Gulfport-Biloxi Regional Airport to Des Moines via Charlotte
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $230–1,100
- Website
- united.com
Flights from Mobile Regional Airport to Des Moines via Houston
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $180–900
Flights from Mobile Regional Airport to Des Moines via Washington Dulles, Chicago O'Hare
- Ave. Duration
- 8h 55m
- When
- Every day
- Estimated price
- $230–1,100
Flights from Pensacola International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 7h 17m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Gulfport-Biloxi Regional Airport to Des Moines via Houston
- Ave. Duration
- 6h 33m
- When
- Every day
- Estimated price
- $200–1,000
- Website
- allegiantair.com
Flights from Destin–Fort Walton Beach Airport to Des Moines
- Ave. Duration
- 2h 25m
- When
- Wednesday
- Estimated price
- $140–800
- Website
- southwest.com
Flights from Pensacola International Airport to Des Moines via St. Louis
- Ave. Duration
- 9h 30m
- When
- Saturday
- Estimated price
- $170–900
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from New Orleans Union Passenger Terminal to Champaign-Urbana
- Ave. Duration
- 16h 20m
- Frequency
- Once daily
- Estimated price
- $110–250
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Mobile to Crestview
- Ave. Duration
- 1h 43m
- Frequency
- Once daily
- Estimated price
- $45–65
- Schedules at
- omnibusexpress.com
Bus from Mobile to Gulfport
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- $45–60
- Schedules at
- omnibusexpress.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Mobile Bus Station to New Orleans Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- 3 times a day
- Estimated price
- $23–35
- Website
- https://www.greyhound.com/
Bus from New Orleans Bus Station to St Louis Bus Station
- Ave. Duration
- 14h 40m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
Bus from Mobile Bus Station to Pensacola Airport
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $25–55
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Mobile Bus Station to New Orleans Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- 6 times a week
- Estimated price
- $24–35
- Schedules at
- flixbus.com
Bus from Mobile Bus Station to Lafayette
- Ave. Duration
- 5h 10m
- Frequency
- 6 times a week
- Estimated price
- $30–90
- Schedules at
- flixbus.com
- Adult
- $30–90
Bus from Lafayette to Memphis Bus Station
- Ave. Duration
- 9h 45m
- Frequency
- 5 times a week
- Estimated price
- $60–110
- Schedules at
- flixbus.com
- Adult
- $60–110
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from St Louis to Burlington
- Ave. Duration
- 4h 35m
- Frequency
- Once daily
- Estimated price
- $50–127
- Website
- https://burlingtontrailways.com
- Saver Fares
- $50–75
- Flexible Fares
- $70–100
- Saver Fare
- $92
- Flex Fare
- $127
Bus from Burlington to Des Moines
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- https://burlingtontrailways.com
- Saver Fares
- $40–60
- Flexible Fares
- $50–80
Bus from Champaign to Des Moines
- Ave. Duration
- 9h 15m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://burlingtontrailways.com
- Saver Fares
- $65–95
- Flexible Fares
- $90–130
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Memphis Bus Station to Kansas City
- Ave. Duration
- 9h 45m
- Frequency
- 4 times a week
- Estimated price
- $45–170
- Book at
- https://www.jeffersonlines.com
Bus from Kansas City to Des Moines
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $18–90
- Book at
- https://www.jeffersonlines.com
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