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How to get fromKey West to Des Moinesby plane, ferry, bus, taxi, shuttle, train or car

Find Transport to Des Moines

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There are 5 ways to get from Key West to Des Moines by plane, ferry, bus, taxi, shuttle, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Key West International Airport (EYW) to Des Moines (DSM)plane plane EYW - DSM
    6h 21m
    $269–1,135

  2. Ferry, bus, taxi

    1. Take the ferry from Key West, FL to Fort Myers Beach, FLferry ferry
    2. Take the bus from Fort Myers to Belle Gladebus bus
    3. Take the taxi from Belle Glade to Three Amigos - Indiantown, FLtaxi taxi
    4. Take the bus from Three Amigos - Indiantown, FL to Lafayettebus bus
    5. Take the bus from Lafayette to Memphis Bus Stationbus bus
    6. Take the bus from Memphis Bus Station to Kansas Citybus bus
    7. Take the bus from Kansas City to Des Moinesbus bus
    2d 5h
    $543–975

  3. Shuttle, train, bus

    1. Take a shuttle bus from Key West, FL to Miami, FL - International Airportshuttle bus
    2. Take the train from Miami Amtrak Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    2d 12h
    $395–1,009

  4. Drive 1,682.5 mi

    1. Drive from Key West to Des Moinescar car 1,682.5 mi
    30h 20m
    $308–444

  5. Bus, train

    1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Miami Amtrak Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Warrensburg Amtrak Stationtrain train
    5. Take the bus from Warrensburg Chamber Of Commerce to Kansas City Bus Stationbus bus
    6. Take the bus from Kansas City to Des Moinesbus bus
    2d 21h
    $336–1,037

Key West to Des Moines by bus, foot, taxi, and train

Calendar7Weekly Services
Duration2d 21hAverage Duration
Ticket$336Cheapest Price
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Questions & Answers

What companies run services between Key West, FL, USA and Des Moines, IA, USA?

Delta, Allegiant Air, and American Airlines fly from Key West International Airport (EYW) to Des Moines (DSM) 5 times a day.

Airlines
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