What is the cheapest way to get from Key West to Des Moines?

The cheapest way to get from Key West to Des Moines is to bus which costs $240 - $600 and takes 45h 46m.

What is the fastest way to get from Key West to Des Moines?

The fastest way to get from Key West to Des Moines is to fly which takes 6h 21m and costs $260 - $1,200.

Is there a direct bus between Key West and Des Moines?

No, there is no direct bus from Key West to Des Moines. However, there are services departing from N Roosevelt & 3rd Street and arriving at Des Moines via Big Pine Key, Miami Airport Station, Atlanta Bus Station and Champaign. The journey, including transfers, takes approximately 45h 46m.

How far is it from Key West to Des Moines?

The distance between Key West and Des Moines is 1374 miles. The road distance is 1692.3 miles.

How do I travel from Key West to Des Moines without a car?

The best way to get from Key West to Des Moines without a car is to bus which takes 45h 46m and costs $240 - $600.

How long does it take to get from Key West to Des Moines?

It takes approximately 6h 21m to get from Key West to Des Moines, including transfers.

Where do I catch the Key West to Des Moines bus from?

Key West to Des Moines bus services, operated by Key West Transit, depart from N Roosevelt & 3rd Street station.

Bus or fly from Key West to Des Moines?

The best way to get from Key West to Des Moines is to fly which takes 6h 21m and costs $260 - $1,200. Alternatively, you can bus, which costs $240 - $600 and takes 45h 46m.

Where does the Key West to Des Moines bus arrive?

Key West to Des Moines bus services, operated by Key West Transit, arrive at Big Pine Key - Auto Store / NAPA MM30 station.

What is the time difference between Key West and Des Moines?

Des Moines is 1h behind Key West. It is currently 3:14 PM in Key West and 2:14 PM in Des Moines.

Can I drive from Key West to Des Moines?

Yes, the driving distance between Key West to Des Moines is 1692 miles. It takes approximately 30h 3m to drive from Key West to Des Moines.

Where can I stay near Des Moines?

There are 235+ hotels available in Des Moines.

Key West to Des Moines - 4 ways to travel via train, plane, bus, and car

There are 4 ways to get from Key West to Des Moines by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly
best
1. Fly from Key West International Airport (EYW) to Des Moines (DSM)plane EYW - DSM
6h 21m
$269–1,135
Bus
cheapest
1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
2. Take the bus from Big Pine Key to Miami Airport Stationbus
3. Take the bus from Miami Airport Station to Atlanta Bus Stationbus
4. Take the bus from Atlanta Bus Station to Champaign Intermodal Trans Ctrbus
5. Take the bus from Champaign to Des Moinesbus
45h 46m
$242–569
Bus, train
1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
2. Take the bus from Big Pine Key to Miami Airport Stationbus
3. Take the train from Miami Amtrak Station to Chicago Union Stationtrain
4. Take the bus from Chicago to Des Moinesbus
2d 13h
$280–957
Drive 1,682.5 mi
1. Drive from Key West to Des Moinescar 1,682.5 mi
30h 3m
$308–444

Key West to Des Moines by bus and foot

7Weekly Services

45h 46mAverage Duration

$242Cheapest Price

See schedules

Questions & Answers

Map of how to get from Key West to Des Moines.

Launch map view

Distance: 1,366 mi
Duration: 6h 21m

What companies run services between Key West, FL, USA and Des Moines, IA, USA?

Delta, American Airlines, and Allegiant Air fly from Key West International Airport (EYW) to Des Moines (DSM) 5 times a day. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Des Moines via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Atlanta Bus Station, Champaign Intermodal Trans Ctr, and Champaign in around 45h 46m.

Airlines

Train operators

Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.