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How to get fromMainz to Santanderby plane, train, bus, or car

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There are 11 ways to get from Mainz to Santander by plane, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Frankfurt to Santander Airport

    best
    1. Fly from Frankfurt (FRA) to Santander Airport (SDR)plane plane FRA - SDR
    6h 18m
    €114–320

  2. Fly Frankfurt to Bilbao Airport, bus

    cheapest
    1. Fly from Frankfurt (FRA) to Bilbao Airport (BIO)plane plane FRA - BIO
    2. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    7h 26m
    €103–266

  3. Train, bus

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhoftrain train 82 / ...
    3. Take the train from Strasbourg to Bordeaux St Jeantrain train Tgv
    4. Take the bus from Bordeaux to Estación de autobuses de Santanderbus bus
    17h 37m
    €272–461

  4. Bus

    1. Take the bus from Mainz central train station to Paris, Quai de Bercy (Bercy Seine)bus bus N90 / ...
    2. Take the bus from Paris to Estación de autobuses de Santanderbus bus FlixBus 783
    21h 15m
    €125–198

  5. Drive  1,483.1 km

    1. Drive from Mainz to Santandercar car 1,483.1 km
    14h 55m
    €243–350

  6. Train to Stuttgart Airport, fly to Bilbao Airport, bus

    1. Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Bilbao Airport (BIO)plane plane STR - BIO
    3. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    9h 10m
    €121–316

  7. Train to Düsseldorf International Airport, fly to Bilbao Airport, bus

    1. Take the train from Frankfurt to Düsseldorf Hbftrain train
    2. Fly from Düsseldorf International Airport (DUS) to Bilbao Airport (BIO)plane plane DUS - BIO
    3. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    9h 24m
    €106–353

  8. Fly Frankfurt to Asturias Airport, bus

    1. Fly from Frankfurt (FRA) to Asturias Airport (OVD)plane plane FRA - OVD
    2. Take the bus from [ANZU|Aeropuerto] Aeropuerto - Salidas [CTA 20118] to [OVIEDO/UVIÉU] Estación Bus Oviedo FL- Pepe Cosmen [CTA 01549]bus bus
    3. Take the bus from Oviedo to Estación de autobuses de Santanderbus bus
    9h 20m
    €134–312

  9. Train, bus via Saint-Jean-de-Luz

    1. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train 55 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhoftrain train 82 / ...
    3. Take the train from Strasbourg to Bordeaux St Jeantrain train Tgv
    4. Take the train from Bordeaux St Jean to St Jean De Luz Cibouretrain train Ter
    5. Take the bus from Saint-Jean-de-Luz to Bilbao Intermodalbus bus
    6. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    18h 19m
    €286–500

  10. Train, bus via Antony

    1. Take the train from Mainz, Hauptbahnhof to Saarbrücken Hbftrain train Re3
    2. Take the train from Saarbrücken Hbf to Paris l'Esttrain train 82
    3. Take the train from Massy Tgv to St Jean De Luz Cibouretrain train Tgv
    4. Take the bus from Saint-Jean-de-Luz to Bilbao Intermodalbus bus
    5. Take the train from Basurto Hospital to Santandertrain train
    18h 50m
    €255–423

  11. Train, bus #2

    1. Take the train from Mainz, Hauptbahnhof to Saarbrücken Hbftrain train Re3
    2. Take the bus from Saarbrücken Hbf to Luxembourgbus bus L40
    3. Take the bus from Luxembourg to Bilbao Intermodalbus bus
    4. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    26h 20m

Mainz to Santander by train, foot, and bus

Calendar7Weekly Services
Duration17h 37mAverage Duration
Ticket€272Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mainz to Santander.ExpandLaunch map view
  • Distance: 1,221.8 km
  • Duration: 6h 18m

What companies run services between Mainz, Germany and Santander, Spain?

Iberia, Condor Flugdienst, and five other airlines fly from Frankfurt (FRA) to Santander Airport (SDR) 4 times a day. Alternatively, you can take a bus from Mainz central train station to Estación de autobuses de Santander via Paris, Quai de Bercy (Bercy Seine) and Paris in around 21h 15m.

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