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How to get fromMainz to Santanderby plane, train, bus, car, train (TGV, Renfe) or night train

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There are 10 ways to get from Mainz to Santander by plane, train, bus, car, train (TGV, Renfe), or night train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Frankfurt to Santander Airport

    best
    1. Fly from Frankfurt (FRA) to Santander Airport (SDR)planeFRA - SDR
    7h 24m
    €147–282
  2. Bus

    cheapest
    1. Take the bus from Mainz central train station to Paris, Quai de Bercy (Bercy Seine)busN90 / ...
    2. Take the bus from Paris to SantanderbusFlixBus 783 / ...
    21h 15m
    €69–192
  3. Train, bus

    1. Take the train from Mainz, Römisches Theater to Mannheim, HauptbahnhoftrainS5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhoftrain82 / ...
    3. Take the train from Strasbourg to Bordeaux St JeantrainTgv
    4. Take the bus from Bordeaux to Santanderbus
    17h 37m
    €181–405
  4. Drive 1,483 km

    1. Drive from Mainz to Santandercar1,483 km
    14h 48m
    €231–334
  5. Fly Frankfurt to Bilbao Airport, bus

    1. Fly from Frankfurt (FRA) to Bilbao Airport (BIO)planeFRA - BIO
    2. Take the bus from Bilbao Intermodal to Santander E.A.bus
    7h 40m
    €111–270
  6. Bus to Hahn, fly to Santander Airport

    1. Take the bus from Mainz Short-term parking lot Am Schlag to Frankfurt Hahn Airportbus
    2. Fly from Hahn (HHN) to Santander Airport (SDR)planeHHN - SDR
    8h 50m
    €97–310
  7. Fly Frankfurt to Biarritz Pays Basque Airport, bus

    1. Fly from Frankfurt (FRA) to Biarritz Pays Basque Airport (BIQ)planeFRA - BIQ
    2. Take the bus from Biarritz - Airport Bus Station to Bilbao Intermodalbus
    3. Take the bus from Bilbao Intermodal to Santander E.A.bus
    10h 5m
  8. Train, bus via Saint-Jean-de-Luz

    1. Take the train from Mainz, Römisches Theater to Mannheim, HauptbahnhoftrainS5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhoftrain82 / ...
    3. Take the train from Strasbourg to Bordeaux St JeantrainTgv
    4. Take the train from Bordeaux St Jean to St Jean De Luz CibouretrainTer
    5. Take the bus from Saint-Jean-de-Luz to Bilbao Intermodalbus
    6. Take the bus from Bilbao Intermodal to Santander E.A.bus
    19h 9m
  9. Train

    1. Take the train from Mainz, Römisches Theater to Mannheim, HauptbahnhoftrainS5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhoftrain82 / ...
    3. Take the train from Strasbourg to Montpellier Saint-RochtrainTgv
    4. Take the train from Montpellier Saint-Roch to Madrid-Puerta de Atocha-Almudena Grandestrain
    5. Take the train from Madrid Chamartín to SantandertrainAlv / ...
    23h 20m
    €236–592
  10. Night train, bus

    1. Take the night train from Mainz Hbf to Brussel-Zuid / Bruxelles-MidinighttrainNj
    2. Take the bus from Brussels - Midi Train Station to Bilbao Intermodalbus
    3. Take the bus from Bilbao Intermodal to Santander E.A.bus
    26h 8m
    €81–416

Mainz to Santander by train, foot, and bus

Calendar7Weekly Services
Duration17h 37mAverage Duration
Ticket€181Cheapest Price
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Questions & Answers

What companies run services between Mainz, Germany and Santander, Spain?

Iberia, Lufthansa, and five other airlines fly from Frankfurt (FRA) to Santander Airport (SDR) 4 times a day. Alternatively, you can take a bus from Mainz central train station to Santander via Paris, Quai de Bercy (Bercy Seine) and Paris in around 21h 15m.

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