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How to get fromMainz to Santanderby plane, train, bus, car or train (TGV, Renfe)

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There are 11 ways to get from Mainz to Santander by plane, train, bus, car, or train (TGV, Renfe)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Frankfurt to Santander Airport

    best
    1. Fly from Frankfurt (FRA) to Santander Airport (SDR)plane plane FRA - SDR
    7h 14m
    €136–342

  2. Bus

    cheapest
    1. Take the bus from Mainz central train station to Paris, Quai de Bercy (Bercy Seine)bus bus N90 / ...
    2. Take the bus from Paris to Santanderbus bus FlixBus 783
    21h 15m
    €102–182

  3. Train, bus

    1. Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain train S5 / ...
    2. Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhoftrain train 82 / ...
    3. Take the train from Strasbourg to Bordeaux St Jeantrain train Tgv
    4. Take the bus from Bordeaux to Santanderbus bus
    17h 38m
    €280–475

  4. Train, bus via Paris

    1. Take the train from Mainz, Hauptbahnhof to Saarbrücken Hbftrain train Re3
    2. Take the train from Saarbrücken Hbf to Paris l'Esttrain train 82 / ...
    3. Take the bus from Paris to Santanderbus bus
    19h 24m
    €157–304

  5. Drive 1,483 km

    1. Drive from Mainz to Santandercar car 1,483 km
    14h 54m
    €231–334

  6. Fly Frankfurt to Bilbao Airport, bus

    1. Fly from Frankfurt (FRA) to Bilbao Airport (BIO)plane plane FRA - BIO
    2. Take the bus from Bilbao Intermodal to Santander E.A.bus bus
    7h 33m
    €114–291

  7. Train to Stuttgart Airport, fly to Bilbao Airport, bus

    1. Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Bilbao Airport (BIO)plane plane STR - BIO
    3. Take the bus from Bilbao Intermodal to Santander E.A.bus bus
    9h 12m
    €121–334

  8. Train to Düsseldorf International Airport, fly to Bilbao Airport, bus

    1. Take the train from Frankfurt to Düsseldorf Hbftrain train
    2. Fly from Düsseldorf International Airport (DUS) to Bilbao Airport (BIO)plane plane DUS - BIO
    3. Take the bus from Bilbao Intermodal to Santander E.A.bus bus
    9h 24m
    €111–354

  9. Fly Frankfurt to Asturias Airport, bus

    1. Fly from Frankfurt (FRA) to Asturias Airport (OVD)plane plane FRA - OVD
    2. Take the bus from [ANZU|Aeropuerto] Aeropuerto - Salidas [CTA 20118] to [OVIEDO/UVIÉU] Estación Bus Oviedo FL- Pepe Cosmen [CTA 01549]bus bus
    3. Take the bus from Oviedo to Santander E.A.bus bus
    8h 51m
    €134–324

  10. Train

    1. Take the train from Frankfurt to Bruxelles Miditrain train 79
    2. Take the train from Brussel-Zuid / Bruxelles-Midi to Montpellier Saint-Rochtrain train Tgv
    3. Take the train from Montpellier Saint-Roch to Madrid-Puerta de Atocha-Almudena Grandestrain train
    4. Take the train from Madrid Chamartín to Santandertrain train Alv / ...
    24h 26m
    €456–804

  11. Train, bus #2

    1. Take the train from Mainz, Hauptbahnhof to Saarbrücken Hbftrain train Re3
    2. Take the bus from Saarbrücken, Hauptbahnhof to Luxembourg, Gare Centrale routièrebus bus L40
    3. Take the bus from Luxembourg to Bilbao Intermodalbus bus
    4. Take the bus from Bilbao Intermodal to Santander E.A.bus bus
    26h 56m

Mainz to Santander by train, foot, and bus

Calendar7Weekly Services
Duration17h 38mAverage Duration
Ticket€280Cheapest Price
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Questions & Answers

What companies run services between Mainz, Germany and Santander, Spain?

Iberia, Lufthansa, and three other airlines fly from Frankfurt (FRA) to Santander Airport (SDR) 4 times a day. Alternatively, you can take a bus from Mainz central train station to Santander via Paris, Quai de Bercy (Bercy Seine) and Paris in around 21h 15m.

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