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How to get fromMainz to Santanderby plane, train, bus, car, or train (Renfe)

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There are 9 ways to get from Mainz to Santander by plane, train, bus, car, or train (Renfe)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Frankfurt to Santander Airport

    best
    1. Fly from Frankfurt (FRA) to Santander Airport (SDR)plane plane FRA - SDR
    6h 58m
    €116–315

  2. Fly Frankfurt to Bilbao Airport, bus

    cheapest
    1. Fly from Frankfurt (FRA) to Bilbao Airport (BIO)plane plane FRA - BIO
    2. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    7h 42m
    €95–282

  3. Train, bus

    1. Take the train from Mainz, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train Re4
    2. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train 83 / ...
    3. Take the train from Strasbourg to Bordeaux St Jeantrain train Tgv
    4. Take the bus from Bordeaux to Estación de autobuses de Santanderbus bus
    17h 36m
    €273–532

  4. Bus

    1. Take the bus from Mainz central train station to Paris, Quai de Bercy (Bercy Seine)bus bus N90 / ...
    2. Take the bus from Paris to Estación de autobuses de Santanderbus bus FlixBus 783
    21h 15m
    €133–201

  5. Drive  1,483.1 km

    1. Drive from Mainz to Santandercar car 1,483.1 km
    14h 55m
    €243–351

  6. Train to Düsseldorf International Airport, fly to Bilbao Airport, bus

    1. Take the train from Frankfurt to Düsseldorf Hbftrain train
    2. Fly from Düsseldorf International Airport (DUS) to Bilbao Airport (BIO)plane plane DUS - BIO
    3. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    9h 49m
    €108–336

  7. Train, bus via Reims

    1. Take the train from Mainz, Hauptbahnhof to Saarbrücken Hbftrain train Re3
    2. Take the train from Saarbrücken Hbf to Champagne-Ardenne TGVtrain train 82
    3. Take the train from Champagne-Ardenne to Bordeaux St Jeantrain train Tgv
    4. Take the train from Bordeaux St Jean to St Jean De Luz Cibouretrain train Ter
    5. Take the bus from Saint-Jean-de-Luz to Bilbao Intermodalbus bus
    6. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    19h 1m
    €267–438

  8. Train

    1. Take the train from Frankfurt to Bruxelles Miditrain train 79
    2. Take the train from Bruxelles-Midi to Nimestrain train Trn
    3. Take the train from Nimes to Madrid-Puerta de Atocha-Almudena Grandestrain train
    4. Take the train from Madrid Chamartín to Santandertrain train Alv / ...
    24h 2m
    €427–717

  9. Train, bus #2

    1. Take the train from Mainz, Hauptbahnhof to Saarbrücken Hbftrain train Re3
    2. Take the bus from Saarbrücken Hbf to Luxembourgbus bus L40
    3. Take the bus from Luxembourg to Bilbao Intermodalbus bus
    4. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    26h 36m

Mainz to Santander by train, foot, and bus

Calendar7Weekly Services
Duration17h 36mAverage Duration
Ticket€273Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mainz to Santander.ExpandLaunch map view
  • Distance: 1,221.8 km
  • Duration: 6h 58m

What companies run services between Mainz, Germany and Santander, Spain?

Iberia, Lufthansa, and five other airlines fly from Frankfurt (FRA) to Santander Airport (SDR) 3 times a day. Alternatively, you can take a bus from Mainz central train station to Estación de autobuses de Santander via Paris, Quai de Bercy (Bercy Seine) and Paris in around 21h 15m.

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