There are 8 ways to get from Mainz to Santander by plane, train, bus, car, or train (TGV, Renfe)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Frankfurt to Santander Airport
best- Fly from Frankfurt (FRA) to Santander Airport (SDR)plane FRA - SDR
7h 24m€136–302Bus
cheapest- Take the bus from Mainz central train station to Paris, Quai de Bercy (Bercy Seine)bus N90 / ...
- Take the bus from Paris to Santanderbus FlixBus 783
21h 15m€95–169Train, bus via Bordeaux
- Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain S5 / ...
- Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhoftrain 82 / ...
- Take the train from Strasbourg to Bordeaux St Jeantrain Tgv
- Take the bus from Bordeaux to Santanderbus
17h 39m€255–451Drive 1,483 km
- Drive from Mainz to Santandercar 1,483 km
14h 53m€234–338Fly Frankfurt to Bilbao Airport, bus
- Fly from Frankfurt (FRA) to Bilbao Airport (BIO)plane FRA - BIO
- Take the bus from Bilbao Intermodal to Santander E.A.bus
7h 38m€104–281Train to Stuttgart Airport, fly to Bilbao Airport, bus
- Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Bilbao Airport (BIO)plane STR - BIO
- Take the bus from Bilbao Intermodal to Santander E.A.bus
9h 18m€113–326Train
- Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain S5 / ...
- Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhoftrain 82 / ...
- Take the train from Strasbourg to Montpellier Saint-Rochtrain Tgv
- Take the train from Montpellier Saint-Roch to Madrid-Puerta de Atocha-Almudena Grandestrain
- Take the train from Madrid Chamartín to Santandertrain Alv / ...
23h 48m€334–593Train, bus
- Take the train from Mainz, Hauptbahnhof to Saarbrücken Hbftrain Re3
- Take the bus from Saarbrücken, Hauptbahnhof to Luxembourg, Gare Centrale routièrebus L40
- Take the bus from Luxembourg to Bilbaobus
- Take the bus from Bilbao Intermodal to Santander E.A.bus
27h 43m
Mainz to Santander by train, foot, and bus
Questions & Answers
The cheapest way to get from Mainz to Santander is to bus which costs €90 - €170 and takes 21h 15m.
The fastest way to get from Mainz to Santander is to fly which takes 7h 24m and costs €130 - €310.
No, there is no direct bus from Mainz station to Santander. However, there are services departing from Mainz central train station and arriving at Santander via Paris. The journey, including transfers, takes approximately 21h 15m.
No, there is no direct train from Mainz to Santander. However, there are services departing from Mainz, Römisches Theater and arriving at Santander via Mannheim, Hauptbahnhof, Strasbourg, Montpellier Saint-Roch, Madrid-Atocha Cercanías and Madrid Chamartín. The journey, including transfers, takes approximately 23h 48m.
The distance between Mainz and Santander is 1222 km. The road distance is 1483 km.
The best way to get from Mainz to Santander without a car is to train and bus via Bordeaux which takes 17h 39m and costs €250 - €460.
It takes approximately 7h 24m to get from Mainz to Santander, including transfers.
Mainz to Santander bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Santander train services, operated by Deutsche Bahn Regio (DB Regional), depart from Mainz, Römisches Theater station.
The best way to get from Mainz to Santander is to fly which takes 7h 24m and costs €130 - €310. Alternatively, you can bus, which costs €90 - €170 and takes 21h 15m, you could also train, which costs €330 - €600 and takes 23h 48m.
What companies run services between Mainz, Germany and Santander, Spain?
Iberia, Air Dolomiti, and four other airlines fly from Frankfurt (FRA) to Santander Airport (SDR) 4 times a day. Alternatively, you can take a bus from Mainz central train station to Santander via Paris, Quai de Bercy (Bercy Seine) and Paris in around 21h 15m.
- Website
- lufthansa.com
Flights from Frankfurt to Bilbao Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- €90–300
Flights from Stuttgart Airport to Bilbao Airport via Frankfurt
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- €100–400
Flights from Stuttgart Airport to Bilbao Airport via Munich
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- €100–410
- Website
- iberia.com
Flights from Frankfurt to Santander Airport via Madrid
- Ave. Duration
- 6h 28m
- When
- Every day
- Estimated price
- €85–480
Flights from Frankfurt to Santander Airport via Barcelona
- Ave. Duration
- 5h 45m
- When
- Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €110–470
Flights from Stuttgart Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 45m
- When
- Thursday, Friday, and Sunday
- Estimated price
- €70–210
- Website
- vueling.com
Flights from Frankfurt to Santander Airport via Barcelona
- Ave. Duration
- 5h 45m
- When
- Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €110–470
Flights from Frankfurt to Santander Airport via Madrid
- Ave. Duration
- 7h 12m
- When
- Every day
- Estimated price
- €85–480
Flights from Stuttgart Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 45m
- When
- Thursday, Friday, and Sunday
- Estimated price
- €70–210
- Website
- airfrance.com
Flights from Frankfurt to Bilbao Airport via Paris Charles de Gaulle
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- €55–330
Flights from Stuttgart Airport to Bilbao Airport via Paris Charles de Gaulle
- Ave. Duration
- 4h 15m
- When
- Tuesday to Friday
- Estimated price
- €65–370
- Website
- swiss.com
Flights from Frankfurt to Bilbao Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- €90–300
Flights from Stuttgart Airport to Bilbao Airport via Zurich
- Ave. Duration
- 4h 40m
- When
- Tuesday and Thursday
- Estimated price
- €60–360
- Website
- ryanair.com
Flights from Frankfurt to Santander Airport via Birmingham
- Ave. Duration
- 5h 35m
- When
- Monday
- Estimated price
- €75–280
- Website
- eurowings.com
Flights from Stuttgart Airport to Bilbao Airport
- Ave. Duration
- 2h
- When
- Tuesday, Friday, and Sunday
- Estimated price
- €70–220
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €14–21
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 53 min
- Frequency
- Once daily
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 1h 9m
- Frequency
- 4 times a day
- Estimated price
- €24–60
- Website
- https://int.bahn.de/en
Train from Mainz, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 1h 37m
- Frequency
- Every 3 hours
- Estimated price
- €30–75
- Website
- https://int.bahn.de/en
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Strasbourg to Bordeaux St Jean
- Ave. Duration
- 6h 1m
- Frequency
- Once daily
- Estimated price
- €190–320
- Website
- https://www.sncf-connect.com/en-en
Train from Strasbourg to Montpellier Saint-Roch
- Ave. Duration
- 6h 3m
- Frequency
- Twice daily
- Estimated price
- €150–250
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Montpellier Saint-Roch to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 6h 44m
- Frequency
- Once daily
- Estimated price
- €100–180
- Website
- https://www.renfe.com/es/en
Train from Madrid Chamartín to Santander
- Ave. Duration
- 4h 20m
- Frequency
- Twice daily
- Estimated price
- €45–80
- Website
- https://www.renfe.com/es/en
- Phone
- +49 6731 999 27-27
- info@vlexx.de
- Website
- vlexx.de
Train from Mainz, Hauptbahnhof to Saarbrücken Hbf
- Ave. Duration
- 2h 17m
- Frequency
- Hourly
- Estimated price
- €29–45
- Schedules at
- vlexx.de
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Bordeaux to Santander
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Estimated price
- €27–50
- Website
- https://www.flixbus.co.uk
Bus from Mainz central train station to Paris, Quai de Bercy (Bercy Seine)
- Ave. Duration
- 7h 25m
- Frequency
- 3 times a day
- Estimated price
- €30–60
- Website
- https://www.flixbus.co.uk
Bus from Paris to Santander
- Ave. Duration
- 12h 50m
- Frequency
- Once daily
- Estimated price
- €60–110
- Website
- https://www.flixbus.co.uk
- Phone
- +34 910 207 007
- alsa@alsa.es
- Website
- alsa.com
Bus from Bilbao Intermodal to Santander E.A.
- Ave. Duration
- 1h 30m
- Frequency
- Every 2 hours
- Estimated price
- €7–16
- Website
- https://www.alsa.com/en/
- Phone
- +352 24 89 24 89
- Website
- cfl.lu
Bus from Saarbrücken, Hauptbahnhof to Luxembourg, Gare Centrale routière
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.cfl.lu/en-gb
- Phone
- +3-389-268-0068
- Website
- blablacar.co.uk
Bus from Luxembourg to Bilbao
- Ave. Duration
- 19h 35m
- Frequency
- Once daily
- Estimated price
- €75–150
- Website
- https://www.blablacar.co.uk/bus
Want to know more about travelling around Spain
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More Questions & Answers
Mainz to Santander bus services, operated by FlixBus, arrive at Paris, Quai de Bercy (Bercy Seine) station.
Mainz to Santander train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Mannheim, Hauptbahnhof station.
Yes, the driving distance between Mainz to Santander is 1483 km. It takes approximately 14h 53m to drive from Mainz to Santander.
Book your Mainz to Santander train tickets online with Omio.
Book your Mainz to Santander bus tickets online with Omio and FlixBus.
There are 2239+ hotels available in Santander.








































