There are 11 ways to get from Mainz to Santander by plane, train, bus, car, or train (TGV, Renfe)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Frankfurt to Santander Airport
best- Fly from Frankfurt (FRA) to Santander Airport (SDR)plane FRA - SDR
6h 18m€100–252Train, bus
- Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain S5 / ...
- Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhoftrain 82 / ...
- Take the train from Strasbourg to Bordeaux St Jeantrain Tgv
- Take the bus from Bordeaux to Estación de autobuses de Santanderbus
17h 39m€239–540Bus
- Take the bus from Mainz central train station to Paris, Quai de Bercy (Bercy Seine)bus N90 / ...
- Take the bus from Paris to Estación de autobuses de Santanderbus FlixBus 783
21h 15m€117–200Drive 1,483 km
- Drive from Mainz to Santandercar 1,483 km
14h 54m€238–343Fly Frankfurt to Bilbao Airport, bus
- Fly from Frankfurt (FRA) to Bilbao Airport (BIO)plane FRA - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
7h 13m€103–252Fly Frankfurt to Asturias Airport, bus
- Fly from Frankfurt (FRA) to Asturias Airport (OVD)plane FRA - OVD
- Take the bus from [ANZU|Aeropuerto] Aeropuerto - Salidas [CTA 20118] to [OVIEDO/UVIÉU] Estación Bus Oviedo FL- Pepe Cosmen [CTA 01549]bus
- Take the bus from Oviedo to Santanderbus
8h 34m€134–279Train to Düsseldorf International Airport, fly to Bilbao Airport, bus
- Take the train from Frankfurt to Düsseldorf Hbftrain
- Fly from Düsseldorf International Airport (DUS) to Bilbao Airport (BIO)plane DUS - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
8h 58m€112–395Train to Stuttgart Airport, fly to Bilbao Airport, bus
- Take the train from Frankfurt to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Bilbao Airport (BIO)plane STR - BIO
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
9h 23m€121–378Train, bus via Reims
- Take the train from Mainz, Hauptbahnhof to Saarbrücken Hbftrain Re3
- Take the train from Saarbrücken Hbf to Champagne-Ardenne TGVtrain 82
- Take the train from Champagne-Ardenne to Bordeaux St Jeantrain Tgv
- Take the train from Bordeaux St Jean to Hendayetrain Ter
- Take the bus from San Sebastián - Bus Station to Santanderbus
18h 8m€248–505Train
- Take the train from Frankfurt to Bruxelles Miditrain 79
- Take the train from Brussel-Zuid / Bruxelles-Midi to Marseille St Charlestrain Tgv
- Take the train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandestrain
- Take the train from Madrid Chamartín to Santandertrain Alv / ...
26h€496–959Train, bus #2
- Take the train from Mainz, Hauptbahnhof to Saarbrücken Hbftrain Re3
- Take the bus from Saarbrücken Hbf to Luxembourgbus L40
- Take the bus from Luxembourg to Bilbaobus
- Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus
26h 33m
Mainz to Santander by train, foot, and bus
Questions & Answers
The cheapest way to get from Mainz to Santander is to bus which costs €110 - €200 and takes 21h 15m.
The fastest way to get from Mainz to Santander is to fly which takes 6h 18m and costs €100 - €260.
No, there is no direct bus from Mainz station to Santander. However, there are services departing from Mainz central train station and arriving at Estación de autobuses de Santander via Paris. The journey, including transfers, takes approximately 21h 15m.
No, there is no direct train from Mainz to Santander. However, there are services departing from Mainz, Römisches Theater and arriving at Santander via Frankfurt, Brussel-Zuid / Bruxelles-Midi, Marseille St Charles, Madrid-Atocha Cercanías and Madrid Chamartín. The journey, including transfers, takes approximately 26h.
The distance between Mainz and Santander is 1222 km. The road distance is 1483 km.
The best way to get from Mainz to Santander without a car is to train and bus which takes 17h 39m and costs €230 - €550.
It takes approximately 6h 18m to get from Mainz to Santander, including transfers.
Mainz to Santander bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Santander train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
The best way to get from Mainz to Santander is to fly which takes 6h 18m and costs €100 - €260. Alternatively, you can bus, which costs €110 - €200 and takes 21h 15m, you could also train, which costs €490 - €1000 and takes 26h.
What companies run services between Mainz, Germany and Santander, Spain?
Iberia, Condor Flugdienst, and five other airlines fly from Frankfurt (FRA) to Santander Airport (SDR) 4 times a day. Alternatively, you can take a bus from Mainz central train station to Estación de autobuses de Santander via Paris, Quai de Bercy (Bercy Seine) and Paris in around 21h 15m.
- Website
- lufthansa.com
Flights from Frankfurt to Bilbao Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- €60–320
Flights from Frankfurt to Asturias Airport
- Ave. Duration
- 2h 20m
- When
- Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €100–230
Flights from Düsseldorf International Airport to Bilbao Airport via Frankfurt
- Ave. Duration
- 3h 55m
- When
- Wednesday
- Estimated price
- €100–390
Flights from Düsseldorf International Airport to Bilbao Airport via Munich
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- €110–400
Flights from Stuttgart Airport to Bilbao Airport via Munich
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- €110–410
- Website
- iberia.com
Flights from Frankfurt to Santander Airport via Madrid
- Ave. Duration
- 5h 53m
- When
- Every day
- Estimated price
- €100–550
Flights from Frankfurt to Santander Airport via Palma Mallorca
- Ave. Duration
- 6h 30m
- When
- Monday to Friday
- Estimated price
- €85–240
Flights from Stuttgart Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 40m
- When
- Saturday and Monday
- Estimated price
- €85–220
- Website
- vueling.com
Flights from Frankfurt to Santander Airport via Madrid
- Ave. Duration
- 5h 53m
- When
- Every day
- Estimated price
- €100–550
Flights from Frankfurt to Santander Airport via Palma Mallorca
- Ave. Duration
- 6h 30m
- When
- Monday to Friday
- Estimated price
- €85–240
Flights from Stuttgart Airport to Bilbao Airport via Barcelona
- Ave. Duration
- 4h 40m
- When
- Saturday and Monday
- Estimated price
- €85–220
- Website
- klm.com
Flights from Frankfurt to Asturias Airport via Amsterdam Schiphol
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- €85–410
Flights from Düsseldorf International Airport to Bilbao Airport via Amsterdam Schiphol
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- €65–350
- Website
- eurowings.com
Flights from Düsseldorf International Airport to Bilbao Airport
- Ave. Duration
- 2h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €75–200
Flights from Stuttgart Airport to Bilbao Airport
- Ave. Duration
- 2h
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €75–200
- Website
- flyulendo.com
Flights from Frankfurt to Santander Airport via Milan Malpensa
- Ave. Duration
- 3h 55m
- When
- Tuesday and Saturday
- Estimated price
- €60–290
- Website
- ryanair.com
Flights from Frankfurt to Santander Airport via Birmingham
- Ave. Duration
- 6h
- When
- Monday and Thursday
- Estimated price
- €80–300
- Website
- lufthansa-city.com
Flights from Frankfurt to Bilbao Airport
- Ave. Duration
- 2h 10m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €60–320
- Website
- luxair.lu
Flights from Frankfurt to Bilbao Airport via Luxembourg
- Ave. Duration
- 5h 5m
- When
- Thursday and Sunday
- Estimated price
- €110–550
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €13–20
- Website
- https://int.bahn.de/en
- Phone
- +49 621 830 1200
- Website
- suewex.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 53 min
- Frequency
- Twice daily
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 1h 9m
- Frequency
- 4 times a day
- Estimated price
- €26–100
- Website
- https://int.bahn.de/en
Train from Frankfurt to Düsseldorf Hbf
- Ave. Duration
- 1h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €35–140
- Website
- https://int.bahn.de/en
Train from Frankfurt to Hauptbahnhof
- Ave. Duration
- 1h 11m
- Frequency
- Hourly
- Estimated price
- €30–130
- Website
- https://int.bahn.de/en
Train from Frankfurt to Bruxelles Midi
- Ave. Duration
- 3h 36m
- Frequency
- Every 4 hours
- Estimated price
- €70–270
- Website
- https://int.bahn.de/en
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Strasbourg to Bordeaux St Jean
- Ave. Duration
- 6h 1m
- Frequency
- 3 times a day
- Estimated price
- €220–360
- Website
- https://www.sncf-connect.com/en-en
Train from Champagne-Ardenne to Bordeaux St Jean
- Ave. Duration
- 4h 36m
- Frequency
- 3 times a day
- Estimated price
- €160–260
- Website
- https://www.sncf-connect.com/en-en
Train from Bordeaux St Jean to Hendaye
- Ave. Duration
- 2h 30m
- Frequency
- Every 3 hours
- Estimated price
- €50–85
- Website
- https://www.sncf-connect.com/en-en
Train from Brussel-Zuid / Bruxelles-Midi to Marseille St Charles
- Ave. Duration
- 5h 31m
- Frequency
- 4 times a day
- Estimated price
- €230–370
- Website
- https://www.sncf-connect.com/en-en
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact DetailsContact Details
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Strasbourg to Bordeaux St Jean
- Ave. Duration
- 5h 45m
- Frequency
- Once a week
- Estimated price
- €170–350
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
Train from Saarbrücken Hbf to Champagne-Ardenne TGV
- Ave. Duration
- 1h 20m
- Frequency
- Once a week
- Estimated price
- €40–85
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
Train from Champagne-Ardenne to Bordeaux St Jean
- Ave. Duration
- 4h 9m
- Frequency
- Once a week
- Estimated price
- €120–250
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
Train from Bordeaux St Jean to Hendaye
- Ave. Duration
- 2h 41m
- Frequency
- Hourly
- Estimated price
- €40–80
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Frankfurt to Düsseldorf Hbf
- Ave. Duration
- 1h 22m
- Frequency
- Every 3 hours
- Estimated price
- €23–50
- Website
- https://www.ns.nl/en
Train from Frankfurt to Hauptbahnhof
- Ave. Duration
- 1h 12m
- Frequency
- 3 times a day
- Estimated price
- €20–45
- Website
- https://www.ns.nl/en
- Phone
- +49 6731 999 27-27
- info@vlexx.de
- Website
- vlexx.de
Train from Mainz, Hauptbahnhof to Saarbrücken Hbf
- Ave. Duration
- 2h 17m
- Frequency
- Hourly
- Estimated price
- €29–45
- Schedules at
- vlexx.de
Train from Mainz, Hauptbahnhof to Saarbrücken Hbf
- Ave. Duration
- 2h 17m
- Frequency
- Hourly
- Estimated price
- €29–45
- Schedules at
- vlexx.de
- Phone
- +32 70 79 79 79
- Website
- belgiantrain.be
Train from Frankfurt to Bruxelles Midi
- Ave. Duration
- 3h 46m
- Frequency
- 4 times a week
- Estimated price
- €65–140
- Website
- https://www.belgiantrain.be/en
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 7h 48m
- Frequency
- Twice daily
- Estimated price
- €140–220
- Website
- https://www.renfe.com/es/en
Train from Madrid Chamartín to Santander
- Ave. Duration
- 4h 27m
- Frequency
- 4 times a day
- Estimated price
- €55–85
- Website
- https://www.renfe.com/es/en
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Bordeaux to Estación de autobuses de Santander
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Estimated price
- €30–60
- Website
- https://www.flixbus.co.uk
Bus from Mainz central train station to Paris, Quai de Bercy (Bercy Seine)
- Ave. Duration
- 7h 25m
- Frequency
- Twice daily
- Estimated price
- €40–70
- Website
- https://www.flixbus.co.uk
Bus from Paris to Estación de autobuses de Santander
- Ave. Duration
- 12h 50m
- Frequency
- Once daily
- Estimated price
- €75–130
- Website
- https://www.flixbus.co.uk
- Phone
- +34 910 207 007
- Website
- alsa.com
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €7–17
- Website
- https://www.alsa.com/en/
Bus from [ANZU|Aeropuerto] Aeropuerto - Salidas [CTA 20118] to [OVIEDO/UVIÉU] Estación Bus Oviedo FL- Pepe Cosmen [CTA 01549]
- Ave. Duration
- 40 min
- Frequency
- Every 30 minutes
- Estimated price
- €3–7
- Website
- https://www.alsa.com/en/
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €7–17
- Website
- https://www.alsa.com/en/
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €7–17
- Website
- https://www.alsa.com/en/
Bus from Bilbao Intermodal to Estación de autobuses de Santander
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €7–17
- Website
- https://www.alsa.com/en/
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Oviedo to Santander
- Ave. Duration
- 1h 59m
- Frequency
- Once daily
- Estimated price
- €16–30
- Website
- https://www.blablacar.co.uk/bus
Bus from San Sebastián - Bus Station to Santander
- Ave. Duration
- 2h 44m
- Frequency
- Once daily
- Estimated price
- €17–30
- Website
- https://www.blablacar.co.uk/bus
Bus from Luxembourg to Bilbao
- Ave. Duration
- 18h 59m
- Frequency
- Once daily
- Estimated price
- €110–200
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +352 24 89 24 89
- Website
- cfl.lu
Bus from Saarbrücken Hbf to Luxembourg
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.cfl.lu/en-gb
Want to know more about travelling around Spain
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More Questions & Answers
Mainz to Santander bus services, operated by FlixBus, arrive at Paris, Quai de Bercy (Bercy Seine) station.
Mainz to Santander train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Bruxelles Midi station.
Yes, the driving distance between Mainz to Santander is 1483 km. It takes approximately 14h 54m to drive from Mainz to Santander.
Book your Mainz to Santander train tickets online with Omio.
Book your Mainz to Santander bus tickets online with Omio and FlixBus.
There are 2632+ hotels available in Santander.






















































