There are 9 ways to get from Mainz to Santander by plane, train, bus, car, or train (TGV, Renfe)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Santander Airport
best- Fly from Frankfurt (FRA) to Santander Airport (SDR)plane FRA - SDR
6h 18m€90–242Train, bus
- Take the train from Mainz, Römisches Theater to Mannheim, Hauptbahnhoftrain S5 / ...
- Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhoftrain 82 / ...
- Take the train from Strasbourg to Bordeaux St Jeantrain Tgv
- Take the bus from Bordeaux to Santanderbus
17h 39m€240–515Bus
- Take the bus from Mainz central train station to Paris, Quai de Bercy (Bercy Seine)bus N90 / ...
- Take the bus from Paris to Santanderbus FlixBus 783
21h 15m€109–204Drive 1,483 km
- Drive from Mainz to Santandercar 1,483 km
14h 54m€239–344Fly to Bilbao Airport, bus
- Fly from Frankfurt (FRA) to Bilbao Airport (BIO)plane FRA - BIO
- Take the bus from Bilbao Intermodal to Santander E.A.bus
8h 8m€103–292Fly to Asturias Airport, bus
- Fly from Frankfurt (FRA) to Asturias Airport (OVD)plane FRA - OVD
- Take the bus from [ANZU|Aeropuerto] Aeropuerto - Salidas [CTA 20118] to [OVIEDO/UVIÉU] Estación Bus Oviedo FL- Pepe Cosmen [CTA 01549]bus
- Take the bus from Oviedo to Santander E.A.bus
8h 50m€132–304Train, bus via Saint-Jean-de-Luz
- Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
- Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhoftrain 82 / ...
- Take the train from Strasbourg to Bordeaux St Jeantrain Tgv
- Take the train from Bordeaux St Jean to St Jean De Luz Cibouretrain Ter
- Take the bus from Saint-Jean-de-Luz to Bilbao Intermodalbus
- Take the bus from Bilbao Intermodal to Santander E.A.bus
18h 11m€256–593Train
- Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain 55 / ...
- Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhoftrain 82 / ...
- Take the train from Strasbourg to Montpellier Saint-Rochtrain Tgv
- Take the train from Montpellier Saint-Roch to Madrid-Puerta de Atocha-Almudena Grandestrain
- Take the train from Madrid Chamartín to Santandertrain Alv / ...
22h 51m€385–665Train, bus #2
- Take the train from Mainz, Hauptbahnhof to Saarbrücken Hbftrain Re3
- Take the bus from Saarbrücken Hbf to Luxembourgbus L40
- Take the bus from Luxembourg to Bilbao Intermodalbus
- Take the bus from Bilbao Intermodal to Santander E.A.bus
26h 25m
Mainz to Santander by train, foot, and bus
Questions & Answers
The cheapest way to get from Mainz to Santander is to bus which costs €100 - €210 and takes 21h 15m.
The fastest way to get from Mainz to Santander is to fly which takes 6h 18m and costs €90 - €250.
No, there is no direct bus from Mainz station to Santander. However, there are services departing from Mainz central train station and arriving at Santander via Paris. The journey, including transfers, takes approximately 21h 15m.
No, there is no direct train from Mainz to Santander. However, there are services departing from Mainz, Hauptbahnhof and arriving at Santander via Mannheim, Hauptbahnhof, Strasbourg, Montpellier Saint-Roch, Madrid-Atocha Cercanías and Madrid Chamartín. The journey, including transfers, takes approximately 22h 51m.
The distance between Mainz and Santander is 1222 km. The road distance is 1483 km.
The best way to get from Mainz to Santander without a car is to train and bus which takes 17h 39m and costs €240 - €550.
It takes approximately 6h 18m to get from Mainz to Santander, including transfers.
Mainz to Santander bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Santander train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mainz, Hauptbahnhof station.
The best way to get from Mainz to Santander is to fly which takes 6h 18m and costs €90 - €250. Alternatively, you can bus, which costs €100 - €210 and takes 21h 15m, you could also train, which costs €380 - €700 and takes 22h 51m.
What companies run services between Mainz, Germany and Santander, Spain?
Iberia, Condor Flugdienst, and five other airlines fly from Frankfurt (FRA) to Santander Airport (SDR) 4 times a day. Alternatively, you can take a bus from Mainz central train station to Santander via Paris, Quai de Bercy (Bercy Seine) and Paris in around 21h 15m.
- Website
- iberia.com
Flights from Frankfurt to Santander Airport via Madrid
- Ave. Duration
- 5h 53m
- When
- Every day
- Estimated price
- €100–550
Flights from Frankfurt to Santander Airport via Palma Mallorca
- Ave. Duration
- 6h 30m
- When
- Monday to Friday
- Estimated price
- €85–200
- Website
- vueling.com
Flights from Frankfurt to Santander Airport via Madrid
- Ave. Duration
- 5h 53m
- When
- Every day
- Estimated price
- €100–550
Flights from Frankfurt to Santander Airport via Palma Mallorca
- Ave. Duration
- 6h 30m
- When
- Monday to Friday
- Estimated price
- €85–200
- Website
- lufthansa.com
Flights from Frankfurt to Bilbao Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- €65–330
Flights from Frankfurt to Asturias Airport
- Ave. Duration
- 2h 20m
- When
- Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €120–230
- Website
- flyulendo.com
Flights from Frankfurt to Santander Airport via Milan Malpensa
- Ave. Duration
- 3h 55m
- When
- Tuesday and Saturday
- Estimated price
- €60–280
- Website
- ryanair.com
Flights from Frankfurt to Santander Airport via Birmingham
- Ave. Duration
- 6h
- When
- Monday and Thursday
- Estimated price
- €80–300
- Website
- lufthansa-city.com
Flights from Frankfurt to Bilbao Airport
- Ave. Duration
- 2h 10m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €65–330
- Website
- luxair.lu
Flights from Frankfurt to Bilbao Airport via Luxembourg
- Ave. Duration
- 5h 5m
- When
- Thursday
- Estimated price
- €100–600
- Website
- airfrance.com
Flights from Frankfurt to Bilbao Airport via Paris Charles de Gaulle
- Ave. Duration
- 5h 20m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €65–340
- Website
- klm.com
Flights from Frankfurt to Asturias Airport via Amsterdam Schiphol
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- €90–410
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €13–21
- Website
- https://int.bahn.de/en
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 21m
- Frequency
- Hourly
- Estimated price
- €14–21
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mainz, Römisches Theater to Mannheim, Hauptbahnhof
- Ave. Duration
- 53 min
- Frequency
- Twice daily
- Estimated price
- €14–20
- Schedules at
- suewex.de
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 54 min
- Frequency
- Every 4 hours
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 1h 9m
- Frequency
- 4 times a day
- Estimated price
- €26–80
- Website
- https://int.bahn.de/en
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 2 hours
- Estimated price
- €12–40
- Website
- https://int.bahn.de/en
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Strasbourg to Bordeaux St Jean
- Ave. Duration
- 6h 1m
- Frequency
- Once daily
- Estimated price
- €230–360
- Website
- https://www.sncf-connect.com/en-en
Train from Bordeaux St Jean to St Jean De Luz Ciboure
- Ave. Duration
- 2h 14m
- Frequency
- 5 times a day
- Estimated price
- €45–80
- Website
- https://www.sncf-connect.com/en-en
Train from Strasbourg to Montpellier Saint-Roch
- Ave. Duration
- 6h 3m
- Frequency
- Twice daily
- Estimated price
- €180–280
- Website
- https://www.sncf-connect.com/en-en
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact Details
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Strasbourg to Bordeaux St Jean
- Ave. Duration
- 5h 45m
- Frequency
- Once a week
- Estimated price
- €170–350
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
Train from Bordeaux St Jean to St Jean De Luz Ciboure
- Ave. Duration
- 2h 26m
- Frequency
- Every 4 hours
- Estimated price
- €35–75
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 46m
- Frequency
- Once daily
- Estimated price
- €7–17
- Website
- https://www.ns.nl/en
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Montpellier Saint-Roch to Madrid-Puerta de Atocha-Almudena Grandes
- Ave. Duration
- 6h 18m
- Frequency
- Once daily
- Estimated price
- €120–180
- Website
- https://www.renfe.com/es/en
Train from Madrid Chamartín to Santander
- Ave. Duration
- 4h 27m
- Frequency
- Twice daily
- Estimated price
- €50–85
- Website
- https://www.renfe.com/es/en
- Phone
- +49 6731 999 27-27
- info@vlexx.de
- Website
- vlexx.de
Train from Mainz, Hauptbahnhof to Saarbrücken Hbf
- Ave. Duration
- 2h 17m
- Frequency
- Hourly
- Estimated price
- €29–45
- Schedules at
- vlexx.de
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Bordeaux to Santander
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Estimated price
- €30–55
- Website
- https://www.flixbus.co.uk
Bus from Mainz central train station to Paris, Quai de Bercy (Bercy Seine)
- Ave. Duration
- 7h 25m
- Frequency
- Twice daily
- Estimated price
- €35–65
- Website
- https://www.flixbus.co.uk
Bus from Paris to Santander
- Ave. Duration
- 12h 50m
- Frequency
- Once daily
- Estimated price
- €70–120
- Website
- https://www.flixbus.co.uk
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Paris to Santander
- Ave. Duration
- 14h 44m
- Frequency
- Twice a week
- Estimated price
- €75–140
- Website
- https://www.blablacar.co.uk/bus
Bus from Bilbao Intermodal to Santander E.A.
- Ave. Duration
- 1h 14m
- Frequency
- Twice a week
- Estimated price
- €7–14
- Website
- https://www.blablacar.co.uk/bus
Bus from Oviedo to Santander E.A.
- Ave. Duration
- 1h 59m
- Frequency
- Twice a week
- Estimated price
- €14–26
- Website
- https://www.blablacar.co.uk/bus
Bus from Saint-Jean-de-Luz to Bilbao Intermodal
- Ave. Duration
- 2h
- Frequency
- Every 4 hours
- Estimated price
- €10–18
- Website
- https://www.blablacar.co.uk/bus
Bus from Luxembourg to Bilbao Intermodal
- Ave. Duration
- 18h 59m
- Frequency
- Once daily
- Estimated price
- €95–180
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +34 910 207 007
- Website
- alsa.com
Bus from Bilbao Intermodal to Santander E.A.
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €7–17
- Website
- https://www.alsa.com/en/
Bus from [ANZU|Aeropuerto] Aeropuerto - Salidas [CTA 20118] to [OVIEDO/UVIÉU] Estación Bus Oviedo FL- Pepe Cosmen [CTA 01549]
- Ave. Duration
- 40 min
- Frequency
- Every 30 minutes
- Estimated price
- €3–7
- Website
- https://www.alsa.com/en/
Bus from Oviedo to Santander E.A.
- Ave. Duration
- 2h 15m
- Frequency
- Every 3 hours
- Estimated price
- €14–35
- Website
- https://www.alsa.com/en/
- Phone
- +352 24 89 24 89
- Website
- cfl.lu
Bus from Saarbrücken Hbf to Luxembourg
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.cfl.lu/en-gb
Want to know more about travelling around Spain
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More Questions & Answers
Mainz to Santander bus services, operated by FlixBus, arrive at Paris, Quai de Bercy (Bercy Seine) station.
Mainz to Santander train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mannheim, Hauptbahnhof station.
Yes, the driving distance between Mainz to Santander is 1483 km. It takes approximately 14h 54m to drive from Mainz to Santander.
Book your Mainz to Santander train tickets online with Omio.
Book your Mainz to Santander bus tickets online with Omio and FlixBus.
There are 2593+ hotels available in Santander.

















































